Intra-thoracic adiposity is associated with impaired contractile function in patients with coronary artery disease: a cardiovascular magnetic resonance imaging study.


Journal

The international journal of cardiovascular imaging
ISSN: 1875-8312
Titre abrégé: Int J Cardiovasc Imaging
Pays: United States
ID NLM: 100969716

Informations de publication

Date de publication:
Jan 2019
Historique:
received: 06 04 2018
accepted: 31 07 2018
pubmed: 6 8 2018
medline: 15 3 2019
entrez: 6 8 2018
Statut: ppublish

Résumé

The influence of visceral adiposity on left ventricular remodeling following coronary artery disease (CAD)-related events has not been examined to date. Using magnetic resonance imaging (MRI) we explored intra-thoracic fat volume (ITFV) and strain-based markers of adverse remodeling in patients with CAD. Forty-seven patients with known CAD (25 with prior MI, 22 without prior MI) were studied. ITFV was quantified using previously validated imaging techniques. Myocardial strain was derived from cine MRI using a validated 3D feature-tracking (FT) software. Segmental LGE quantification was performed and was used to incrementally constrain strain analyses to non-infarcted (i.e. remote) segments. Remote myocardial strain was compared to the non-MI control cohort and was explored for associations with ITFV. Mean age was 57 ± 13 years with a mean BMI of 30.0 ± 6.2 kg/m

Identifiants

pubmed: 30078132
doi: 10.1007/s10554-018-1430-1
pii: 10.1007/s10554-018-1430-1
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

121-131

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Auteurs

Anna Todd (A)

Stephenson Cardiac Imaging Centre, Suite 0700 Foothills Medical Centre - 1403 29th St NW, Calgary, AB, T2N 2T9, Canada.
Division of Cardiology, Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, Calgary, AB, Canada.

Alessandro Satriano (A)

Stephenson Cardiac Imaging Centre, Suite 0700 Foothills Medical Centre - 1403 29th St NW, Calgary, AB, T2N 2T9, Canada.
Division of Cardiology, Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, Calgary, AB, Canada.

Kate Fenwick (K)

Stephenson Cardiac Imaging Centre, Suite 0700 Foothills Medical Centre - 1403 29th St NW, Calgary, AB, T2N 2T9, Canada.

Naeem Merchant (N)

Department of Diagnostic Imaging, University of Calgary, Calgary, AB, Canada.

Carmen P Lydell (CP)

Department of Diagnostic Imaging, University of Calgary, Calgary, AB, Canada.

Andrew G Howarth (AG)

Stephenson Cardiac Imaging Centre, Suite 0700 Foothills Medical Centre - 1403 29th St NW, Calgary, AB, T2N 2T9, Canada.
Division of Cardiology, Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, Calgary, AB, Canada.

Matthias G Friedrich (MG)

McGill University Health Centre, Montreal, QC, Canada.

Todd J Anderson (TJ)

Division of Cardiology, Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, Calgary, AB, Canada.

Nowell M Fine (NM)

Division of Cardiology, Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, Calgary, AB, Canada.

James A White (JA)

Stephenson Cardiac Imaging Centre, Suite 0700 Foothills Medical Centre - 1403 29th St NW, Calgary, AB, T2N 2T9, Canada. jawhit@ucalgary.ca.
Division of Cardiology, Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, Calgary, AB, Canada. jawhit@ucalgary.ca.

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