Interaction between plasma homocysteine and the MTHFR c.677C > T polymorphism is associated with site-specific changes in DNA methylation in humans.

Aged Chromosome Mapping Cohort Studies DNA Methylation Dietary Supplements Epigenesis, Genetic Female Genome-Wide Association Study Homocysteine / blood Humans Male Methylenetetrahydrofolate Reductase (NADPH2) / genetics Middle Aged Polymorphism, Genetic Twin Studies as Topic Vitamins / administration & dosage
1-carbon metabolism epigenetics methylenetetrahydrofolate reductase methylome-wide association study vascular disease

Journal

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
ISSN: 1530-6860
Titre abrégé: FASEB J
Pays: United States
ID NLM: 8804484

Informations de publication

Date de publication:
01 2019
Historique:
pubmed: 7 8 2018
medline: 20 8 2019
entrez: 7 8 2018
Statut: ppublish

Résumé

One-carbon metabolism provides a direct link among dietary folate/vitamin B

Identifiants

DOI: 10.1096/fj.201800400R PMID: 30080444
pubmed: 30080444
doi: 10.1096/fj.201800400R
doi:

Substances chimiques

Vitamins 0
Homocysteine 0LVT1QZ0BA
Methylenetetrahydrofolate Reductase (NADPH2) EC 1.5.1.20

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Pagination

833-843

Auteurs

Alexander J Nash (AJ)

Institute of Clinical Sciences and Medical Research Council (MRC) London Institute of Medical Sciences, Imperial College, London, United Kingdom.

Pooja R Mandaviya (PR)

Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands.
Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

Marie-Joe Dib (MJ)

Department of Genomics of Common Disease, Imperial College, London, United Kingdom; and.

André G Uitterlinden (AG)

Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

Joyce van Meurs (J)

Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

Sandra G Heil (SG)

Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands.

Toby Andrew (T)

Department of Genomics of Common Disease, Imperial College, London, United Kingdom; and.

Kourosh R Ahmadi (KR)

Department of Nutritional Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, United Kingdom.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Interaction between plasma homocysteine and...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Cartographie chromosomique › Interaction between plasma homocysteine and...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Interaction between plasma homocysteine and...
questionsmedicales.fr › Phénomènes génétiques › Méthylation de l'ADN › Interaction between plasma homocysteine and...
questionsmedicales.fr › Aliments et boissons › Aliments › Compléments alimentaires › Interaction between plasma homocysteine and...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Interaction between plasma homocysteine and...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Épidémiologie moléculaire › Étude d'association pangénomique › Interaction between plasma homocysteine and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés soufrés › Homocystéine › Interaction between plasma homocysteine and...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Interaction between plasma homocysteine and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Flavoprotéines › Methylenetetrahydrofolate reductase (NADPH2) › Interaction between plasma homocysteine and...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Interaction between plasma homocysteine and...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Polymorphisme génétique › Interaction between plasma homocysteine and...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Méthode des jumeaux comme sujet › Interaction between plasma homocysteine and...
questionsmedicales.fr › Aliments et boissons › Aliments › Nutriments › Micronutriments › Vitamines › Interaction between plasma homocysteine and...