Combined Early and Late [


Journal

Molecular imaging and biology
ISSN: 1860-2002
Titre abrégé: Mol Imaging Biol
Pays: United States
ID NLM: 101125610

Informations de publication

Date de publication:
06 2019
Historique:
pubmed: 15 8 2018
medline: 6 5 2020
entrez: 15 8 2018
Statut: ppublish

Résumé

Our aim was to evaluate the benefit of early (1 h post-injection (p.i.)) and late (3 h p.i.) [ Seventy patients with BCR of the PCa and prostate-specific antigen (PSA) levels of less than 2.0 μg/l were subjected to [ Forty-four of the 70 patients thus examined were interpreted as PSMA-positive in early and/or late scans while 26 remained without suspicion of PSMA tracer uptake. A total of 70 suspicious lesions were analyzed. Ten tumor-suspicious lesions from seven different patients were better or exclusively visible in the late measurements while three tumor-suspicious lesions from three different patients were better or exclusively visible in the early images. A validation by follow-up data was possible for 11 of these 13 additionally detected lesions. In direct comparison between early and late imaging, the mean SUV The time period between injection and data acquisition influences the detection rate of [

Identifiants

pubmed: 30105521
doi: 10.1007/s11307-018-1263-2
pii: 10.1007/s11307-018-1263-2
doi:

Substances chimiques

N,N'-bis(2-hydroxy-5-(ethylene-beta-carboxy)benzyl)ethylenediamine N,N'-diacetic acid 143557-99-7
Edetic Acid 9G34HU7RV0
Prostate-Specific Antigen EC 3.4.21.77

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

558-566

Références

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Auteurs

M Hohberg (M)

Department of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany. Melanie.Hohberg@uk-koeln.de.
Cancer Center Cologne, University Hospital of Cologne, Cologne, Germany. Melanie.Hohberg@uk-koeln.de.

C Kobe (C)

Department of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Cancer Center Cologne, University Hospital of Cologne, Cologne, Germany.

P Täger (P)

Department of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Cancer Center Cologne, University Hospital of Cologne, Cologne, Germany.

J Hammes (J)

Department of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Cancer Center Cologne, University Hospital of Cologne, Cologne, Germany.

M Schmidt (M)

Department of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Cancer Center Cologne, University Hospital of Cologne, Cologne, Germany.

F Dietlein (F)

Department of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.

M Wild (M)

Department of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.

A Heidenreich (A)

Cancer Center Cologne, University Hospital of Cologne, Cologne, Germany.
Department of Urology, University Hospital of Cologne, Cologne, Germany.

A Drzezga (A)

Department of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Cancer Center Cologne, University Hospital of Cologne, Cologne, Germany.

M Dietlein (M)

Department of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Cancer Center Cologne, University Hospital of Cologne, Cologne, Germany.

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