Mango phenolics increase the serum apolipoprotein A1/B ratio in rats fed high cholesterol and sodium cholate diets.
cholesterol
hepatoprotection
lipoprotein
liver
mango
rat
Journal
Journal of the science of food and agriculture
ISSN: 1097-0010
Titre abrégé: J Sci Food Agric
Pays: England
ID NLM: 0376334
Informations de publication
Date de publication:
15 Mar 2019
15 Mar 2019
Historique:
received:
27
02
2018
revised:
24
08
2018
accepted:
27
08
2018
pubmed:
7
9
2018
medline:
21
3
2019
entrez:
7
9
2018
Statut:
ppublish
Résumé
Serum lipoproteins are in dynamic equilibrium, partially controlled by the apolipoprotein A1 to apolipoprotein B ratio (APOA1/APOB). Freeze-dried mango pulp (FDM) is a rich source of phenolic compounds (MP) and dietary fiber (MF), although their effects on lipoprotein metabolism have not yet been studied. Thirty male Wistar rats were fed with four different isocaloric diets (3.4 kcal g We propose that phenolics are the most bioactive components of mango pulp, acting as anti-atherogenic and hepatoprotective agents, with a mechanism of action tentatively based on changes to the main protein components of lipoproteins. © 2018 Society of Chemical Industry.
Sections du résumé
BACKGROUND
BACKGROUND
Serum lipoproteins are in dynamic equilibrium, partially controlled by the apolipoprotein A1 to apolipoprotein B ratio (APOA1/APOB). Freeze-dried mango pulp (FDM) is a rich source of phenolic compounds (MP) and dietary fiber (MF), although their effects on lipoprotein metabolism have not yet been studied.
RESULTS
RESULTS
Thirty male Wistar rats were fed with four different isocaloric diets (3.4 kcal g
CONCLUSION
CONCLUSIONS
We propose that phenolics are the most bioactive components of mango pulp, acting as anti-atherogenic and hepatoprotective agents, with a mechanism of action tentatively based on changes to the main protein components of lipoproteins. © 2018 Society of Chemical Industry.
Substances chimiques
Apolipoprotein A-I
0
Apolipoproteins B
0
Plant Extracts
0
Phenol
339NCG44TV
Cholesterol
97C5T2UQ7J
Sodium Cholate
NU3Y4CCH8Z
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1604-1612Subventions
Organisme : Consejo Nacional de Ciencia y Tecnología
ID : Fonteras de la Ciencia 563: "Un Enfoque Multidis
Organisme : Programa Integral de Fortalecimiento Institucional
ID : 2909 5001-004-09
Informations de copyright
© 2018 Society of Chemical Industry.