Perioperative cardiovascular complications following urogynecological operations.


Journal

Acta obstetricia et gynecologica Scandinavica
ISSN: 1600-0412
Titre abrégé: Acta Obstet Gynecol Scand
Pays: United States
ID NLM: 0370343

Informations de publication

Date de publication:
01 2019
Historique:
received: 09 05 2018
revised: 13 08 2018
accepted: 27 08 2018
pubmed: 7 9 2018
medline: 29 10 2019
entrez: 7 9 2018
Statut: ppublish

Résumé

The risk of perioperative cardiovascular complications following operations for urinary incontinence and pelvic organ prolapse (POP) must be taken into consideration during surgical planning. The literature on the cardiovascular risk following urinary incontinence and POP operations shows conflicting results. Our aims were to provide an estimate of the mortality and the risk of cardiovascular complications following urinary incontinence and POP operations considering women's preoperative cardiovascular comorbidity. This nationwide register-based study includes a total of 13 992 operations for urinary incontinence and 35 765 for POP from 2007 to 2017. The risk was estimated as an incidence/rate ratio for women with and without former cardiovascular comorbidity adjusted for relevant confounders by using a case-crossover study design. A total of 7677 patients were at high risk, with a cardiovascular comorbidity prior to the operation, and 42 076 patients were at low risk, with no cardiovascular comorbidity. Overall, 11 patients died within 30 days following an operation, of whom five were in the high-risk group and six in the low-risk group. Of the women at high risk, 0.59% had cardiovascular complications from 0 to 6 days following an operation, corresponding to an incidence/rate ratio of 3.64 (95% CI; 2.67-4.97), compared with women at low risk where no complications were registered in the first week. We found an increased risk of cardiovascular complications following urogynecological operations in women with preoperative cardiovascular comorbidity, and no increased risk in women without prior cardiovascular comorbidity. In general, the risk of cardiovascular complications was lower than that found in previous studies.

Identifiants

pubmed: 30187912
doi: 10.1111/aogs.13457
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

61-67

Subventions

Organisme : Odense University Hospital Free Research Fund
Pays : International

Informations de copyright

© 2018 Nordic Federation of Societies of Obstetrics and Gynecology.

Auteurs

Michael Due Larsen (MD)

Center for Clinical Epidemiology, Odense University Hospital, Odense, Denmark.
Research Unit of Clinical Epidemiology, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.

Rikke Guldberg (R)

Department of Obstetrics and Gynecology, Aarhus University Hospital, Aarhus, Denmark.

Gunnar Lose (G)

Gynecology and Obstetrics Department, Herlev Hospital and University of Copenhagen, Copenhagen, Denmark.

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Classifications MeSH