The occurrence of intraoperative complications during partial nephrectomy and their impact on postoperative outcome: results from the RECORd1 project.


Journal

Minerva urologica e nefrologica = The Italian journal of urology and nephrology
ISSN: 1827-1758
Titre abrégé: Minerva Urol Nefrol
Pays: Italy
ID NLM: 8503649

Informations de publication

Date de publication:
Feb 2019
Historique:
pubmed: 12 9 2018
medline: 9 4 2019
entrez: 12 9 2018
Statut: ppublish

Résumé

The aim of this study was to analyze the predictive factors of intraoperative complications in patients submitted to PN and the impact of intraoperative complications on postoperative outcomes. Data of 1055 patients who underwent PN for cortical renal masses were recorded from a multicenter prospective observational study (RECORd1 project). Overall, 48 (5%) patients experienced 49 intraoperative complications (four medical, 45 surgical). At multivariable analysis, age (OR=1.02, 95% CI: 1.00-1.08, P=0.03), imperative versus elective surgical indication (OR=2.55, 95% CI: 1.12-5.85, P=0.03), open (OR=5.76, 95% CI: 1.05-9.21, P=0.01) and laparoscopic (OR=2.35, 95% CI: 1.11-4.95, P=0.03) versus robotic approaches resulted independent predictive factors of intraoperative complications. Patients experiencing intraoperative complications had a significantly higher rate of overall postoperative complications (41.6% vs. 17.3%, P<0.0001), surgical postoperative complications (29.2% vs. 12.6%, P<0.0001), Clavien 2 surgical postoperative complications (14.6% vs. 7.2%, P=0.05) and a significantly longer length of stay (8 [6-9] vs. 7 [5-8] days, P<0.0001) than those with an uneventful intraoperative course. Efforts should be made to minimize the risk of intraoperative complications during PN, and, in that case, patients should be carefully monitored.

Sections du résumé

BACKGROUND BACKGROUND
The aim of this study was to analyze the predictive factors of intraoperative complications in patients submitted to PN and the impact of intraoperative complications on postoperative outcomes.
METHODS METHODS
Data of 1055 patients who underwent PN for cortical renal masses were recorded from a multicenter prospective observational study (RECORd1 project).
RESULTS RESULTS
Overall, 48 (5%) patients experienced 49 intraoperative complications (four medical, 45 surgical). At multivariable analysis, age (OR=1.02, 95% CI: 1.00-1.08, P=0.03), imperative versus elective surgical indication (OR=2.55, 95% CI: 1.12-5.85, P=0.03), open (OR=5.76, 95% CI: 1.05-9.21, P=0.01) and laparoscopic (OR=2.35, 95% CI: 1.11-4.95, P=0.03) versus robotic approaches resulted independent predictive factors of intraoperative complications. Patients experiencing intraoperative complications had a significantly higher rate of overall postoperative complications (41.6% vs. 17.3%, P<0.0001), surgical postoperative complications (29.2% vs. 12.6%, P<0.0001), Clavien 2 surgical postoperative complications (14.6% vs. 7.2%, P=0.05) and a significantly longer length of stay (8 [6-9] vs. 7 [5-8] days, P<0.0001) than those with an uneventful intraoperative course.
CONCLUSIONS CONCLUSIONS
Efforts should be made to minimize the risk of intraoperative complications during PN, and, in that case, patients should be carefully monitored.

Identifiants

pubmed: 30203939
pii: S0393-2249.18.03202-2
doi: 10.23736/S0393-2249.18.03202-2
doi:

Types de publication

Journal Article Multicenter Study Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

47-54

Auteurs

Andrea Minervini (A)

Department of Urology, Careggi Hospital, University of Florence, Florence, Italy - andreamine@libero.it.

Andrea Mari (A)

Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.

Marco Borghesi (M)

Department of Urology, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

Alessandro Antonelli (A)

Department of Urology, Spedali Civili Hospital, Brescia, Italy.

Riccardo Bertolo (R)

Department of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Turin, Italy.

Giampaolo Bianchi (G)

Department of Urology, Polyclinic of Modena, University of Modena, Modena, Italy.

Eugenio Brunocilla (E)

Department of Urology, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

Vincenzo Ficarra (V)

Department of Urology, University of Padua, Padua, Italy.

Cristian Fiori (C)

Department of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Turin, Italy.

Nicola Longo (N)

Department of Urology, Federico II Hospital, University of Naples, Naples, Italy.

Vincenzo Mirone (V)

Department of Urology, Federico II Hospital, University of Naples, Naples, Italy.

Giuseppe Morgia (G)

Department of Urology, University of Catania, Catania, Italy.

Francesco Porpiglia (F)

Department of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Turin, Italy.

Bernardo Rocco (B)

Department of Urology, Ca' Granda Foundation and Insitute for Research and Care, Maggiore Polyclinic Hospital, University of Milan, Milan, Italy.

Sergio Serni (S)

Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.

Claudio Simeone (C)

Department of Urology, Spedali Civili Hospital, Brescia, Italy.

Riccardo Tellini (R)

Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.

Alessandro Volpe (A)

Department of Urology, Maggiore della Carità Hospital, Novara, Italia.

Marco Carini (M)

Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.

Riccardo Schiavina (R)

Department of Urology, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

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