SOX9/FXYD3/Src Axis Is Critical for ER

Animals Breast Neoplasms / genetics Cell Nucleus / metabolism Female Heterografts Humans MCF-7 Cells Membrane Proteins / biosynthesis Mice Mice, Inbred NOD Mice, SCID Neoplasm Proteins / biosynthesis Neoplastic Stem Cells / metabolism Receptors, Estrogen / metabolism SOX9 Transcription Factor / genetics Signal Transduction src-Family Kinases / metabolism

Journal

Molecular cancer research : MCR
ISSN: 1557-3125
Titre abrégé: Mol Cancer Res
Pays: United States
ID NLM: 101150042

Informations de publication

Date de publication:
01 2019
Historique:
received: 09 06 2018
revised: 01 08 2018
accepted: 30 08 2018
pubmed: 13 9 2018
medline: 24 1 2020
entrez: 13 9 2018
Statut: ppublish

Résumé

The presence of cancer stem cells (CSC), which possess the ability of self-renewal and cancer initiation, is correlated with poor prognosis and drug resistance of breast cancer patients. But the molecular regulatory networks for maintenance of CSC function still remain unclear. Here, we identified that an estrogen-inducible gene

Identifiants

DOI: 10.1158/1541-7786.MCR-18-0610 PMID: 30206184
pubmed: 30206184
pii: 1541-7786.MCR-18-0610
doi: 10.1158/1541-7786.MCR-18-0610
doi:

Substances chimiques

FXYD3 protein, human 0
Membrane Proteins 0
Neoplasm Proteins 0
Receptors, Estrogen 0
SOX9 Transcription Factor 0
SOX9 protein, human 0
src-Family Kinases EC 2.7.10.2

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

238-249

Informations de copyright

©2018 American Association for Cancer Research.

Auteurs

Yue Xue (Y)

Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, China.

Lihua Lai (L)

Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, China.

Wenwen Lian (W)

Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, China.

Xintao Tu (X)

Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, China.

Jiaojiao Zhou (J)

Department of Oncology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

Ping Dong (P)

Department of Neurobiology, Institute of Neuroscience, Zhejiang University School of Medicine, Hangzhou, China.
ORCID: 0000-0002-6640-6607

Dan Su (D)

Zhejiang Cancer Hospital, Hangzhou, China.

Xiaojia Wang (X)

Zhejiang Cancer Hospital, Hangzhou, China.

Xuetao Cao (X)

Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, China.
National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.

Yiding Chen (Y)

Department of Oncology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

Qingqing Wang (Q)

Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, China. wqq@zju.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Maladies du sein › Tumeurs du sein › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Noyau de la cellule › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Régions du corps › Transplants › Hétérogreffes › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › Cellules MCF-7 › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée NOD › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souches mutantes de souris › Souris SCID › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines tumorales › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Cellules › Cellules souches › Cellules souches tumorales › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Récepteurs aux stéroïdes › Récepteurs des oestrogènes › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription SOX › Facteurs de transcription SOX-E › Facteur de transcription SOX-9 › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › SOX9/FXYD3/Src Axis Is Critical for ER
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-tyrosine kinases › src-Family kinases › SOX9/FXYD3/Src Axis Is Critical for ER