Artificial nutrition in patients with cancer has no impact on tumour glucose metabolism: Results of the PETANC Study.


Journal

Clinical nutrition (Edinburgh, Scotland)
ISSN: 1532-1983
Titre abrégé: Clin Nutr
Pays: England
ID NLM: 8309603

Informations de publication

Date de publication:
10 2019
Historique:
received: 14 03 2018
revised: 16 07 2018
accepted: 25 08 2018
pubmed: 14 9 2018
medline: 26 9 2020
entrez: 14 9 2018
Statut: ppublish

Résumé

Nutrition support is recommended in cachexic patients with cancer. However, there is no clear evidence about its impact on tumour growth. Glycolysis, which is usually higher in cancer than normal cells, can be monitored by This prospective study included ten patients with histologically proven head and neck or oesophageal cancer. All patients underwent Artificial nutrition (median energy intake of 21.83 kcal/kg/day [13.16-45.90], protein intake of 0.84 g/kg/day [0.56-1.64]) was administered. Eight patients (80%) received enteral nutrition and two patients (20%) parenteral support. Comparison of In cachexic patients with head and neck or oesophageal cancer, nutrition support administered according to the current guidelines shows no impact on tumour glucose metabolism, assessed by

Sections du résumé

BACKGROUND & AIMS
Nutrition support is recommended in cachexic patients with cancer. However, there is no clear evidence about its impact on tumour growth. Glycolysis, which is usually higher in cancer than normal cells, can be monitored by
METHODS
This prospective study included ten patients with histologically proven head and neck or oesophageal cancer. All patients underwent
RESULTS
Artificial nutrition (median energy intake of 21.83 kcal/kg/day [13.16-45.90], protein intake of 0.84 g/kg/day [0.56-1.64]) was administered. Eight patients (80%) received enteral nutrition and two patients (20%) parenteral support. Comparison of
CONCLUSIONS
In cachexic patients with head and neck or oesophageal cancer, nutrition support administered according to the current guidelines shows no impact on tumour glucose metabolism, assessed by

Identifiants

pubmed: 30209026
pii: S0261-5614(18)32427-0
doi: 10.1016/j.clnu.2018.08.033
pii:
doi:

Substances chimiques

Blood Glucose 0
Fluorodeoxyglucose F18 0Z5B2CJX4D
Glucose IY9XDZ35W2

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2121-2126

Informations de copyright

Copyright © 2018 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Auteurs

Emmanuel Deshayes (E)

Nuclear Medicine Department, Institut du Cancer de Montpellier, Univ. Montpellier, Montpellier, France; Institut de Recherche en Cancérologie de Montpellier (IRCM), INSERM U1194, Univ. Montpellier, Institut du Cancer de Montpellier (ICM), Montpellier, France. Electronic address: emmanuel.deshayes@icm.unicancer.fr.

Hélène de Forges (H)

Clinical Research Unit, Institut du Cancer de Montpellier, Univ. Montpellier, Montpellier, France.

Julien Fraisse (J)

Biometrics Unit, Institut du Cancer de Montpellier, Univ. Montpellier, Montpellier, France.

Marie-Claude Eberlé (MC)

Nuclear Medicine Department, Institut du Cancer de Montpellier, Univ. Montpellier, Montpellier, France.

Sophie Guillemard (S)

Nuclear Medicine Department, Institut du Cancer de Montpellier, Univ. Montpellier, Montpellier, France.

Anne Fallières (A)

Clinical Nutrition and Gastroenterology Department, Institut du Cancer de Montpellier, Univ. Montpellier, Montpellier, France.

Jean-Pierre Pouget (JP)

Institut de Recherche en Cancérologie de Montpellier (IRCM), INSERM U1194, Univ. Montpellier, Institut du Cancer de Montpellier (ICM), Montpellier, France.

Raphaël Tétreau (R)

Radiology Department, Institut du Cancer de Montpellier, Univ. Montpellier, Montpellier, France.

Pierre-Olivier Kotzki (PO)

Nuclear Medicine Department, Institut du Cancer de Montpellier, Univ. Montpellier, Montpellier, France; Institut de Recherche en Cancérologie de Montpellier (IRCM), INSERM U1194, Univ. Montpellier, Institut du Cancer de Montpellier (ICM), Montpellier, France.

Lore Santoro (L)

Nuclear Medicine Department, Institut du Cancer de Montpellier, Univ. Montpellier, Montpellier, France.

Pierre Senesse (P)

Clinical Nutrition and Gastroenterology Department, Institut du Cancer de Montpellier, Univ. Montpellier, Montpellier, France.

Nicolas Flori (N)

Clinical Nutrition and Gastroenterology Department, Institut du Cancer de Montpellier, Univ. Montpellier, Montpellier, France.

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Classifications MeSH