Adjuvant treatments associated with botulinum toxin injection for managing spasticity: An overview of the literature.
Athletic Tape
Botulinum Toxins, Type A
/ therapeutic use
Casts, Surgical
Combined Modality Therapy
Electric Stimulation Therapy
Extracorporeal Shockwave Therapy
Humans
Immobilization
Muscle Spasticity
/ drug therapy
Neuromuscular Agents
/ therapeutic use
Orthotic Devices
Randomized Controlled Trials as Topic
Splints
Vibration
/ therapeutic use
Botulinum toxins
Muscle spasticity
Physical therapy modalities
Rehabilitation
Journal
Annals of physical and rehabilitation medicine
ISSN: 1877-0665
Titre abrégé: Ann Phys Rehabil Med
Pays: Netherlands
ID NLM: 101502773
Informations de publication
Date de publication:
Jul 2019
Jul 2019
Historique:
received:
11
12
2017
revised:
20
08
2018
accepted:
20
08
2018
pubmed:
17
9
2018
medline:
28
1
2020
entrez:
17
9
2018
Statut:
ppublish
Résumé
A wide range of adjunct therapies after botulinum toxin administration have been proposed. The aim of the present paper is to provide an overview of major writings dealing with adjuvant (non-pharmacological) treatments associated with botulinum toxin for managing spasticity in order to provide some up-to-date information about the usefulness of the most commonly used procedures. The literature in PubMed was searched with the MeSH terms botulinum toxins, muscle spasticity, physical therapy modalities, and rehabilitation. The results were limited to studies focusing on adjuvant treatments associated with botulinum toxin for managing spasticity. We excluded papers on the use of non-drug treatments for spasticity not associated with botulinum toxin serotype A (BoNT-A) injection. Relevant literature known to the authors along with this complementary search represented the basis for this overview of the literature. Adhesive taping and casting effectively improved the botulinum toxin effect in patients with upper- and lower-limb spasticity. There is level 1 evidence that casting is better than taping for outcomes including spasticity, range of motion and gait. However, consensus about their most appropriate timing, duration, target and material is lacking. In terms of physical modalities combined with botulinum toxin injection, we found level 1 evidence that extracorporeal shock wave therapy is better than electrical stimulation for some post-injection outcomes including spasticity and pain. Furthermore, electrical stimulation of injected muscles might be useful to boost the toxin effect. However, the best stimulation protocol has not been defined. In addition, we found level 2b evidence that whole-body vibration therapy might reduce spasticity with cerebral palsy. Future research in this field should focus on investigating the most appropriate post-injection treatment protocol for each goal to achieve.
Sections du résumé
BACKGROUND AND OBJECTIVE
OBJECTIVE
A wide range of adjunct therapies after botulinum toxin administration have been proposed. The aim of the present paper is to provide an overview of major writings dealing with adjuvant (non-pharmacological) treatments associated with botulinum toxin for managing spasticity in order to provide some up-to-date information about the usefulness of the most commonly used procedures.
METHODS
METHODS
The literature in PubMed was searched with the MeSH terms botulinum toxins, muscle spasticity, physical therapy modalities, and rehabilitation. The results were limited to studies focusing on adjuvant treatments associated with botulinum toxin for managing spasticity. We excluded papers on the use of non-drug treatments for spasticity not associated with botulinum toxin serotype A (BoNT-A) injection. Relevant literature known to the authors along with this complementary search represented the basis for this overview of the literature.
RESULTS
RESULTS
Adhesive taping and casting effectively improved the botulinum toxin effect in patients with upper- and lower-limb spasticity. There is level 1 evidence that casting is better than taping for outcomes including spasticity, range of motion and gait. However, consensus about their most appropriate timing, duration, target and material is lacking. In terms of physical modalities combined with botulinum toxin injection, we found level 1 evidence that extracorporeal shock wave therapy is better than electrical stimulation for some post-injection outcomes including spasticity and pain. Furthermore, electrical stimulation of injected muscles might be useful to boost the toxin effect. However, the best stimulation protocol has not been defined. In addition, we found level 2b evidence that whole-body vibration therapy might reduce spasticity with cerebral palsy.
CONCLUSION
CONCLUSIONS
Future research in this field should focus on investigating the most appropriate post-injection treatment protocol for each goal to achieve.
Identifiants
pubmed: 30219307
pii: S1877-0657(18)31445-3
doi: 10.1016/j.rehab.2018.08.004
pii:
doi:
Substances chimiques
Neuromuscular Agents
0
Botulinum Toxins, Type A
EC 3.4.24.69
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
291-296Informations de copyright
Copyright © 2018 Elsevier Masson SAS. All rights reserved.