Dynamic platelet function is markedly different in patients with cancer compared to healthy donors.

Female Humans Male Middle Aged Neoplasms / blood Platelet Function Tests / methods Tissue Donors von Willebrand Factor / metabolism
Blood platelets cancer platelet function tests von Willebrand factor

Journal

Platelets
ISSN: 1369-1635
Titre abrégé: Platelets
Pays: England
ID NLM: 9208117

Informations de publication

Date de publication:
2019
Historique:
pubmed: 27 9 2018
medline: 18 12 2019
entrez: 26 9 2018
Statut: ppublish

Résumé

Despite a fivefold increased risk of thromboembolism in patients with cancer, the mechanism of arterial thromboembolism is poorly understood. To address this, we investigated platelet function in cancer patients and healthy controls using an assay that mimics the arterial vasculature. Blood samples from cancer patients (

Identifiants

DOI: 10.1080/09537104.2018.1513475 PMID: 30252557
pubmed: 30252557
doi: 10.1080/09537104.2018.1513475
doi:

Substances chimiques

von Willebrand Factor 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

737-742

Auteurs

Jonathan Cowman (J)

a Molecular and Cellular Therapeutics , The Royal College of Surgeons in Ireland , Dublin , Ireland.

Louis Richter (L)

a Molecular and Cellular Therapeutics , The Royal College of Surgeons in Ireland , Dublin , Ireland.

Roisin Walsh (R)

a Molecular and Cellular Therapeutics , The Royal College of Surgeons in Ireland , Dublin , Ireland.

Niamh Keegan (N)

b Department of Medical Oncology , Beaumont Hospital , Dublin , Ireland.

Willard Tinago (W)

c HIV Molecular Research Group , University College Dublin , Dublin , Ireland.

Antonio J Ricco (AJ)

d The Biomedical Diagnostics Institute, Dublin City University , Dublin , Ireland.

Bryan T Hennessy (BT)

b Department of Medical Oncology , Beaumont Hospital , Dublin , Ireland.

Dermot Kenny (D)

a Molecular and Cellular Therapeutics , The Royal College of Surgeons in Ireland , Dublin , Ireland.
ORCID: 0000-0001-5548-3263

Eimear Dunne (E)

a Molecular and Cellular Therapeutics , The Royal College of Surgeons in Ireland , Dublin , Ireland.
ORCID: 0000-0001-9862-1398

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Dynamic platelet function is markedly...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Dynamic platelet function is markedly...
questionsmedicales.fr › Tumeurs › Dynamic platelet function is markedly...
questionsmedicales.fr › Techniques d'investigation › Techniques de laboratoire clinique › Tests hématologiques › Tests fonctionnels plaquettaires › Dynamic platelet function is markedly...
questionsmedicales.fr › Personnes › Donneurs de tissus › Dynamic platelet function is markedly...
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Facteur de von Willebrand › Dynamic platelet function is markedly...