Synthesis,

Animals Claudin-4 / antagonists & inhibitors Enterotoxins / chemical synthesis Fluorine Radioisotopes / chemistry HT29 Cells Humans Isotope Labeling Ligands Male Mice Mice, Nude Molecular Imaging Molecular Mimicry / physiology Molecular Targeted Therapy Neoplasms / drug therapy Positron-Emission Tomography Rats Rats, Wistar Solid-Phase Synthesis Techniques
18F-fluorobenzoylation Claudin family of tight junction proteins Difficult peptide sequences Molecular imaging Radiolabelled peptides Small animal positron emission tomography

Journal

Amino acids
ISSN: 1438-2199
Titre abrégé: Amino Acids
Pays: Austria
ID NLM: 9200312

Informations de publication

Date de publication:
Feb 2019
Historique:
received: 14 08 2018
accepted: 17 09 2018
pubmed: 29 9 2018
medline: 15 6 2019
entrez: 29 9 2018
Statut: ppublish

Résumé

The cell surface receptor claudin-4 (Cld-4) is upregulated in various tumours and represents an important emerging target for both diagnosis and treatment of solid tumours of epithelial origin. The C-terminal fragment of the Clostridium perfringens enterotoxin cCPE

Identifiants

DOI: 10.1007/s00726-018-2657-9 PMID: 30264172
pubmed: 30264172
doi: 10.1007/s00726-018-2657-9
pii: 10.1007/s00726-018-2657-9
doi:

Substances chimiques

Claudin-4 0
Enterotoxins 0
Fluorine Radioisotopes 0
Ligands 0
enterotoxin, Clostridium 0
Fluorine-18 GZ5I74KB8G

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

219-244

Auteurs

Reik Löser (R)

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden Rossendorf, Bautzner Landstraße 400, 01328, Dresden, Germany. r.loeser@hzdr.de.
Faculty of Chemistry and Food Chemistry, School of Science, Technische Universität Dresden, Mommsenstraße 4, 01062, Dresden, Germany. r.loeser@hzdr.de.
ORCID: 0000-0003-1531-7601

Miriam Bader (M)

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden Rossendorf, Bautzner Landstraße 400, 01328, Dresden, Germany.
Faculty of Chemistry and Food Chemistry, School of Science, Technische Universität Dresden, Mommsenstraße 4, 01062, Dresden, Germany.

Manuela Kuchar (M)

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden Rossendorf, Bautzner Landstraße 400, 01328, Dresden, Germany.
Faculty of Chemistry and Food Chemistry, School of Science, Technische Universität Dresden, Mommsenstraße 4, 01062, Dresden, Germany.

Robert Wodtke (R)

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden Rossendorf, Bautzner Landstraße 400, 01328, Dresden, Germany.
Faculty of Chemistry and Food Chemistry, School of Science, Technische Universität Dresden, Mommsenstraße 4, 01062, Dresden, Germany.

Jens Lenk (J)

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden Rossendorf, Bautzner Landstraße 400, 01328, Dresden, Germany.
Faculty of Chemistry and Food Chemistry, School of Science, Technische Universität Dresden, Mommsenstraße 4, 01062, Dresden, Germany.

Johanna Wodtke (J)

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden Rossendorf, Bautzner Landstraße 400, 01328, Dresden, Germany.

Konstantin Kuhne (K)

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden Rossendorf, Bautzner Landstraße 400, 01328, Dresden, Germany.
Faculty of Chemistry and Food Chemistry, School of Science, Technische Universität Dresden, Mommsenstraße 4, 01062, Dresden, Germany.

Ralf Bergmann (R)

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden Rossendorf, Bautzner Landstraße 400, 01328, Dresden, Germany.

Cathleen Haase-Kohn (C)

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden Rossendorf, Bautzner Landstraße 400, 01328, Dresden, Germany.

Marie Urbanová (M)

Department of Physics and Measurements, University of Chemistry and Technology, 166 28, Prague, Czech Republic.

Jörg Steinbach (J)

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden Rossendorf, Bautzner Landstraße 400, 01328, Dresden, Germany.
Faculty of Chemistry and Food Chemistry, School of Science, Technische Universität Dresden, Mommsenstraße 4, 01062, Dresden, Germany.

Jens Pietzsch (J)

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden Rossendorf, Bautzner Landstraße 400, 01328, Dresden, Germany.
Faculty of Chemistry and Food Chemistry, School of Science, Technische Universität Dresden, Mommsenstraße 4, 01062, Dresden, Germany.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Synthesis,
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de la jonction serrée › Claudines › Claudine-4 › Synthesis,
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Entérotoxines › Synthesis,
questionsmedicales.fr › Produits chimiques inorganiques › Isotopes › Radio-isotopes › Radio-isotopes du fluor › Synthesis,
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HT29 › Synthesis,
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Synthesis,
questionsmedicales.fr › Techniques d'investigation › Marquage isotopique › Synthesis,
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › Synthesis,
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Synthesis,
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souches mutantes de souris › Souris nude › Synthesis,
questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Imagerie moléculaire › Synthesis,
questionsmedicales.fr › Phénomènes biologiques › Adaptation biologique › Mimétisme biologique › Mimétisme moléculaire › Synthesis,
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Thérapie moléculaire ciblée › Synthesis,
questionsmedicales.fr › Tumeurs › Synthesis,
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Synthesis,
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Synthesis,
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Wistar › Synthesis,
questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Technologie pharmaceutique › Techniques de chimie synthétique › Techniques de synthèse en phase solide › Synthesis,