A paper-based chemiresistive biosensor employing single-walled carbon nanotubes for low-cost, point-of-care detection.

Biosensing Techniques Carboxylic Acids / chemistry Humans Limit of Detection Nanotubes, Carbon / chemistry Point-of-Care Systems Pyrenes / chemistry Serum Albumin, Human / chemistry
Biosensors Chemiresistive Low-cost Paper-based Point-of-care Single-walled carbon nanotubes

Journal

Biosensors & bioelectronics
ISSN: 1873-4235
Titre abrégé: Biosens Bioelectron
Pays: England
ID NLM: 9001289

Informations de publication

Date de publication:
01 Apr 2019
Historique:
received: 01 07 2018
revised: 07 09 2018
accepted: 12 09 2018
pubmed: 1 10 2018
medline: 7 6 2019
entrez: 1 10 2018
Statut: ppublish

Résumé

Paper-based biosensors are promising for low-cost diagnostics. However, its widespread use has been hampered due to a lack of sensitive detection methods that can be easily implemented on paper substrates. On the other hand, single-walled carbon nanotubes (SWNTs) -based chemiresistive biosensors are gaining popularity as label-free, highly sensitive biosensors. However, traditional SWNT-based chemiresistors need to be more affordable for use in resource-limited settings. In this study, we report fabrication, optimization and analytical characterization of a chemiresistive biosensor on paper for label-free immunosensing. We synthesized a water-based ink using pyrene carboxylic acid (PCA) through non-covalent π-π stacking interaction between PCA and SWNTs. The PCA/SWNTs ink concentration can reach ~4 mg mL

Identifiants

DOI: 10.1016/j.bios.2018.09.041 PMID: 30268670
pubmed: 30268670
pii: S0956-5663(18)30729-2
doi: 10.1016/j.bios.2018.09.041
pii:
doi:

Substances chimiques

Carboxylic Acids 0
Nanotubes, Carbon 0
Pyrenes 0
pyrene 9E0T7WFW93
Serum Albumin, Human ZIF514RVZR

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

367-373

Informations de copyright

Copyright © 2018 Elsevier B.V. All rights reserved.

Auteurs

Yu Shen (Y)

Department of Chemical and Environmental Engineering, University of California, Riverside, CA 92521, USA.

Thien-Toan Tran (TT)

Department of Bioengineering, University of California, Riverside, CA 92521, USA.

Sidharth Modha (S)

Department of Bioengineering, University of California, Riverside, CA 92521, USA.

Hideaki Tsutsui (H)

Department of Mechanical Engineering, University of California, Riverside, CA 92521, USA.

Ashok Mulchandani (A)

Department of Chemical and Environmental Engineering, University of California, Riverside, CA 92521, USA; Materials Science and Engineering Program, University of California, Riverside, CA 92521, USA. Electronic address: adani@engr.ucr.edu.

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Techniques de biocapteur › A paper-based chemiresistive biosensor...
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › A paper-based chemiresistive biosensor...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A paper-based chemiresistive biosensor...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Sensibilité et spécificité › Limite de détection › A paper-based chemiresistive biosensor...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanotubes › Nanotubes de carbone › A paper-based chemiresistive biosensor...
questionsmedicales.fr › Administration des services de santé › Gestion des soins aux patients › Systèmes automatisés lit malade › A paper-based chemiresistive biosensor...
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Pyrènes › A paper-based chemiresistive biosensor...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du sang › Sérumalbumine › Sérum-albumine humaine › A paper-based chemiresistive biosensor...