Impact of test protocols and material binding on the efficacy of antimicrobial wipes.
Efficacy
Material
Test protocols
Wipes
Journal
The Journal of hospital infection
ISSN: 1532-2939
Titre abrégé: J Hosp Infect
Pays: England
ID NLM: 8007166
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
19
07
2018
accepted:
24
09
2018
pubmed:
3
10
2018
medline:
31
12
2019
entrez:
2
10
2018
Statut:
ppublish
Résumé
The use of effective cleaning/disinfectant products is important to control pathogens on healthcare surfaces. With the increasing number of wipe products available, there is a concern that combination of a formulation with the wrong material will decrease the efficacy of the product. This study aimed to use a range of efficacy test protocols to determine the efficacy of four formulations before and after binding to three commonly used wiping materials. Two quaternary ammonium (QAC)-based products, one hydrogen-peroxide-based product and one neutral cleaner were combined with microfibre, cotton or non-woven materials and tested for efficacy against Pseudomonas aeruginosa and Staphylococcus aureus with two surface tests (ASTM E2197-17 and EN13697-15) and two 'product' tests (ASTM E2967-15 and EN16615-15). Overall, the impact of using different materials on formulation efficacy was limited, except for an alkyl(C The use of different wiping cloth materials may not impact severely on the efficacy of potent disinfectants, despite the absorption of different volumes of formulation by the materials. QAC-based formulations may be at higher risk when a low concentration is used. There were large differences in efficacy depending on the standard test performed, highlighting the need for more stringency in choosing the test to make a product claim on label.
Sections du résumé
BACKGROUND
BACKGROUND
The use of effective cleaning/disinfectant products is important to control pathogens on healthcare surfaces. With the increasing number of wipe products available, there is a concern that combination of a formulation with the wrong material will decrease the efficacy of the product. This study aimed to use a range of efficacy test protocols to determine the efficacy of four formulations before and after binding to three commonly used wiping materials.
METHODS
METHODS
Two quaternary ammonium (QAC)-based products, one hydrogen-peroxide-based product and one neutral cleaner were combined with microfibre, cotton or non-woven materials and tested for efficacy against Pseudomonas aeruginosa and Staphylococcus aureus with two surface tests (ASTM E2197-17 and EN13697-15) and two 'product' tests (ASTM E2967-15 and EN16615-15).
FINDINGS
RESULTS
Overall, the impact of using different materials on formulation efficacy was limited, except for an alkyl(C
CONCLUSIONS
CONCLUSIONS
The use of different wiping cloth materials may not impact severely on the efficacy of potent disinfectants, despite the absorption of different volumes of formulation by the materials. QAC-based formulations may be at higher risk when a low concentration is used. There were large differences in efficacy depending on the standard test performed, highlighting the need for more stringency in choosing the test to make a product claim on label.
Identifiants
pubmed: 30273639
pii: S0195-6701(18)30507-3
doi: 10.1016/j.jhin.2018.09.016
pii:
doi:
Substances chimiques
Disinfectants
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e25-e32Informations de copyright
Copyright © 2018 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.