The Muscarinic Acetylcholine Receptor M

Allosteric Regulation / drug effects Animals Drug Discovery / methods Humans Muscarinic Agonists / pharmacology Muscarinic Antagonists / pharmacology Nervous System Diseases / drug therapy Receptor, Muscarinic M5 / agonists Substance-Related Disorders / drug therapy
Alzheimer’s disease M5 addiction allosteric modulator knockout muscarinic schizophrenia

Journal

ACS chemical neuroscience
ISSN: 1948-7193
Titre abrégé: ACS Chem Neurosci
Pays: United States
ID NLM: 101525337

Informations de publication

Date de publication:
20 03 2019
Historique:
pubmed: 4 10 2018
medline: 7 3 2020
entrez: 4 10 2018
Statut: ppublish

Résumé

The muscarinic acetylcholine receptor (mAChR) subtype 5 (M

Identifiants

DOI: 10.1021/acschemneuro.8b00481 PMID: 30280567
pubmed: 30280567
doi: 10.1021/acschemneuro.8b00481
doi:

Substances chimiques

Muscarinic Agonists 0
Muscarinic Antagonists 0
Receptor, Muscarinic M5 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1025-1034

Auteurs

Aaron M Bender (AM)

Vanderbilt Center for Neuroscience Drug Discovery , Vanderbilt University Medical Center , Nashville , Tennessee 37232 , United States.
Department of Pharmacology , Vanderbilt University School of Medicine , Nashville , Tennessee 37232 , United States.

Aaron T Garrison (AT)

Vanderbilt Center for Neuroscience Drug Discovery , Vanderbilt University Medical Center , Nashville , Tennessee 37232 , United States.
Department of Pharmacology , Vanderbilt University School of Medicine , Nashville , Tennessee 37232 , United States.

Craig W Lindsley (CW)

Vanderbilt Center for Neuroscience Drug Discovery , Vanderbilt University Medical Center , Nashville , Tennessee 37232 , United States.
Department of Pharmacology , Vanderbilt University School of Medicine , Nashville , Tennessee 37232 , United States.
ORCID: 0000-0003-0168-1445

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Classifications MeSH

questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Régulation allostérique › The Muscarinic Acetylcholine Receptor M
questionsmedicales.fr › Eucaryotes › Animaux › The Muscarinic Acetylcholine Receptor M
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Découverte de médicament › The Muscarinic Acetylcholine Receptor M
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The Muscarinic Acetylcholine Receptor M
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents cholinergiques › Agonistes cholinergiques › Agonistes muscariniques › The Muscarinic Acetylcholine Receptor M
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents cholinergiques › Antagonistes cholinergiques › Antagonistes muscariniques › The Muscarinic Acetylcholine Receptor M
questionsmedicales.fr › Maladies du système nerveux › The Muscarinic Acetylcholine Receptor M
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs cholinergiques › Récepteur muscarinique › Récepteur muscarinique de type M5 › The Muscarinic Acetylcholine Receptor M
questionsmedicales.fr › Troubles mentaux › Troubles liés à une substance › The Muscarinic Acetylcholine Receptor M