Doxorubicin-loaded casein nanoparticles for drug delivery: Preparation, characterization and in vitro evaluation.

Caseins / chemistry Doxorubicin / chemistry Drug Carriers / chemistry Drug Liberation Hydrogen-Ion Concentration Micelles Nanoparticles / chemistry Polyethylene Glycols / chemistry
Casein nanoparticles Drug delivery Intrinsically unstructured protein

Journal

International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578

Informations de publication

Date de publication:
Jan 2019
Historique:
received: 19 07 2018
revised: 18 09 2018
accepted: 01 10 2018
pubmed: 6 10 2018
medline: 22 1 2019
entrez: 6 10 2018
Statut: ppublish

Résumé

Casein, a milk protein that self-assembles to form micelles in aqueous solution, can bind to a wide range of drugs (hydrophilic and hydrophobic). Herein, a low cost and facile method was reported to prepare casein nanoparticles loaded with an anticancer drug, doxorubicin (DOX). The particles were fabricated by adding an excess of Ca

Identifiants

DOI: 10.1016/j.ijbiomac.2018.10.005 PMID: 30290258
pubmed: 30290258
pii: S0141-8130(18)33706-1
doi: 10.1016/j.ijbiomac.2018.10.005
pii:
doi:

Substances chimiques

Caseins 0
Drug Carriers 0
Micelles 0
Polyethylene Glycols 3WJQ0SDW1A
Doxorubicin 80168379AG

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

6-12

Informations de copyright

Copyright © 2018. Published by Elsevier B.V.

Auteurs

Sona Gandhi (S)

Department of Chemistry, University of Delhi, Delhi 110007, India.

Indrajit Roy (I)

Department of Chemistry, University of Delhi, Delhi 110007, India. Electronic address: indrajitroy11@gmail.com.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Phosphoprotéines › Caséines › Doxorubicin-loaded casein nanoparticles for...
questionsmedicales.fr › Glucides › Hétérosides › Aminosides › Anthracyclines › Daunorubicine › Doxorubicine › Doxorubicin-loaded casein nanoparticles for...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Vecteurs de médicaments › Doxorubicin-loaded casein nanoparticles for...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Pharmacocinétique › Libération de médicament › Doxorubicin-loaded casein nanoparticles for...
questionsmedicales.fr › Phénomènes chimiques › Concentration en ions d'hydrogène › Doxorubicin-loaded casein nanoparticles for...
questionsmedicales.fr › Préparations pharmaceutiques › Micelles › Doxorubicin-loaded casein nanoparticles for...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanoparticules › Doxorubicin-loaded casein nanoparticles for...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Polyéthylène glycols › Doxorubicin-loaded casein nanoparticles for...