Misidentification of Burkholderia pseudomallei as Acinetobacter species in northern Thailand.


Journal

Transactions of the Royal Society of Tropical Medicine and Hygiene
ISSN: 1878-3503
Titre abrégé: Trans R Soc Trop Med Hyg
Pays: England
ID NLM: 7506129

Informations de publication

Date de publication:
01 01 2019
Historique:
received: 25 06 2018
accepted: 10 09 2018
pubmed: 9 10 2018
medline: 21 1 2020
entrez: 9 10 2018
Statut: ppublish

Résumé

Burkholderia pseudomallei is the causative agent of melioidosis, a disease endemic throughout the tropics. A study of reported Acinetobacter spp. bacteraemia was performed at Chiang Rai provincial hospital from 2014 to 2015. Isolates were collected and tested for confirmation. A total of 419 putative Acinetobacter spp. isolates from 412 patients were re-identified and 5/419 (1.2%) were identified as B. pseudomallei. Four of the five patients with melioidosis died. An estimated 88/419 (21%) isolates were correctly identified as Acinetobacter spp. Misidentification of Acinetobacter spp. as B. pseudomallei or other bacteria is not uncommon and programmes to address these shortfalls are urgently required.

Sections du résumé

Background
Burkholderia pseudomallei is the causative agent of melioidosis, a disease endemic throughout the tropics.
Methods
A study of reported Acinetobacter spp. bacteraemia was performed at Chiang Rai provincial hospital from 2014 to 2015. Isolates were collected and tested for confirmation.
Results
A total of 419 putative Acinetobacter spp. isolates from 412 patients were re-identified and 5/419 (1.2%) were identified as B. pseudomallei. Four of the five patients with melioidosis died. An estimated 88/419 (21%) isolates were correctly identified as Acinetobacter spp.
Conclusions
Misidentification of Acinetobacter spp. as B. pseudomallei or other bacteria is not uncommon and programmes to address these shortfalls are urgently required.

Identifiants

pubmed: 30295891
pii: 5116252
doi: 10.1093/trstmh/try108
pmc: PMC6314150
doi:

Types de publication

Case Reports Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

48-51

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom

Références

PLoS Negl Trop Dis. 2010 Nov 30;4(11):e900
pubmed: 21152057
J Antimicrob Chemother. 2004 Dec;54(6):1134-8
pubmed: 15509614
Int J Antimicrob Agents. 2001 Feb;17(2):109-13
pubmed: 11165114
Clin Microbiol Infect. 2018 Jan;24(1):84.e1-84.e4
pubmed: 28780059
Emerg Infect Dis. 2012 Dec;18(12):e2
pubmed: 23171644
N Engl J Med. 2012 Sep 13;367(11):1035-44
pubmed: 22970946
Emerg Infect Dis. 2015 Feb;21(2):null
pubmed: 25626057
Nat Microbiol. 2016 Jan 11;1:15008
pubmed: 27571754

Auteurs

Rachel C Greer (RC)

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Tri Wangrangsimakul (T)

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Premjit Amornchai (P)

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

Vanaporn Wuthiekanun (V)

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

Achara Laongnualpanich (A)

Chiang Rai Prachanukroh Hospital, Chiang Rai, Thailand.

David A B Dance (DAB)

Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Vientiane Capital, Lao People's Democratic Republic.
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.

Direk Limmathurotsakul (D)

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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Classifications MeSH