Expression, Purification, and Activity Analysis of Chlorophyllide Oxidoreductase and Ni

Chlorophyll biosynthesis Chlorophyllide oxidoreductase (COR) Coenzyme F430 biosynthesis Dynamic switch protein Ni2+-sirohydrochlorin a,c-diamide reductase (CfbC/D) Nitrogenase-like enzymes

Journal

Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969

Informations de publication

Date de publication:
2019
Historique:
entrez: 15 10 2018
pubmed: 15 10 2018
medline: 14 6 2019
Statut: ppublish

Résumé

Nitrogenase-like enzymes play a vital role in the reduction of the conjugated ring systems of diverse tetrapyrrole molecules. The biosynthesis of all bacteriochlorophylls involves the two-electron reduction of the C7-C8 double bond of the green pigment chlorophyllide, which is catalyzed by the nitrogenase-like two-component metalloenzyme chlorophyllide oxidoreductase (COR); whereas in all methanogenic microbes, another nitrogenase-like system, CfbC/D, is responsible for the sophisticated six-electron reduction of Ni

Identifiants

pubmed: 30317478
doi: 10.1007/978-1-4939-8864-8_8
doi:

Substances chimiques

Metalloporphyrins 0
Metalloproteins 0
Multienzyme Complexes 0
Uroporphyrins 0
Chlorophyll 1406-65-1
sirohydrochlorin 65207-12-7
factor F430 73145-13-8
Nickel 7OV03QG267
Alcohol Oxidoreductases EC 1.1.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

125-140

Auteurs

Jürgen Moser (J)

Institut für Mikrobiologie, Technische Universität Braunschweig, Braunschweig, Germany. j.moser@tu-bs.de.

Jan Jasper (J)

Institut für Mikrobiologie, Technische Universität Braunschweig, Braunschweig, Germany.

José Vazquez Ramos (JV)

Institut für Biochemie, Universität Leipzig, Leipzig, Germany.

Sven T Sowa (ST)

Institut für Biochemie, Universität Leipzig, Leipzig, Germany.

Gunhild Layer (G)

Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany. gunhild.layer@pharmazie.uni-freiburg.de.

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Classifications MeSH