Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate.

Adenocarcinoma / genetics Animals Epigenomics / methods Humans Male Mice Prostatic Neoplasms / genetics

Journal

Molecular cancer research : MCR
ISSN: 1557-3125
Titre abrégé: Mol Cancer Res
Pays: United States
ID NLM: 101150042

Informations de publication

Date de publication:
02 2019
Historique:
received: 30 04 2018
revised: 24 08 2018
accepted: 09 10 2018
pubmed: 20 10 2018
medline: 28 1 2020
entrez: 19 10 2018
Statut: ppublish

Résumé

Among prostate cancers containing Gleason pattern 4, cribriform morphology is associated with unfavorable clinicopathologic factors, but its genetic features and association with long-term outcomes are incompletely understood. In this study, genetic, transcriptional, and epigenetic features of invasive cribriform carcinoma (ICC) tumors were compared with non-cribriform Gleason 4 (NC4) in The Cancer Genome Atlas (TCGA) cohort. ICC (

Identifiants

DOI: 10.1158/1541-7786.MCR-18-0440 PMID: 30333152 PMC: PMC6359952
pubmed: 30333152
pii: 1541-7786.MCR-18-0440
doi: 10.1158/1541-7786.MCR-18-0440
pmc: PMC6359952
mid: NIHMS1509826
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

446-456

Subventions

Organisme : NCI NIH HHS
ID : P50 CA090381
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA187918
Pays : United States
Organisme : NCI NIH HHS
ID : U01 CA167552
Pays : United States
Organisme : NCI NIH HHS
ID : R37 CA215040
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA131945
Pays : United States
Organisme : NCI NIH HHS
ID : K08 CA187417
Pays : United States
Organisme : NCI NIH HHS
ID : P50 CA211024
Pays : United States
Organisme : NCI NIH HHS
ID : UM1 CA167552
Pays : United States

Informations de copyright

©2018 American Association for Cancer Research.

Références

Oncol Lett. 2017 Jul;14(1):390-396
pubmed: 28693181
Am J Clin Pathol. 2011 Jul;136(1):98-107
pubmed: 21685037
Cancer Chemother Rep. 1966 Mar;50(3):125-8
pubmed: 5948714
Am J Surg Pathol. 2016 Feb;40(2):244-52
pubmed: 26492179
Oncotarget. 2017 Jan 3;8(1):379-392
pubmed: 27880722
Nat Genet. 2012 May 20;44(6):685-9
pubmed: 22610119
Elife. 2015 Oct 27;4:
pubmed: 26506153
Cell Rep. 2013 Aug 15;4(3):516-29
pubmed: 23890999
Mod Pathol. 2015 Mar;28(3):457-64
pubmed: 25189638
Clin Cancer Res. 2014 Sep 15;20(18):4925-34
pubmed: 25056375
Cancer Res. 2015 Mar 15;75(6):1021-34
pubmed: 25770290
Cancer Epidemiol Biomarkers Prev. 2012 Sep;21(9):1497-509
pubmed: 22736790
Diagn Pathol. 2016 Mar 09;11:25
pubmed: 26956509
BMC Cancer. 2018 Jan 2;18(1):8
pubmed: 29295717
Mod Pathol. 2015 Jan;28(1):128-137
pubmed: 24993522
Int J Cancer. 2007 Oct 1;121(7):1571-8
pubmed: 17450530
Elife. 2015 Sep 16;4:
pubmed: 26374986
Cancer Treat Rev. 2015 Nov;41(9):761-6
pubmed: 26210103
Protein Cell. 2013 May;4(5):331-41
pubmed: 23636686
Nat Genet. 2000 May;25(1):25-9
pubmed: 10802651
JAMA Oncol. 2016 Dec 1;2(12):1598-1606
pubmed: 27148695
J Urol. 2016 Feb;195(2):313-20
pubmed: 26327354
Cancer Res. 2012 Feb 1;72(3):616-25
pubmed: 22158653
Nucleic Acids Res. 2017 Jan 4;45(D1):D353-D361
pubmed: 27899662
J Clin Oncol. 2009 Jul 20;27(21):3459-64
pubmed: 19433685
Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2110-5
pubmed: 10051603
J Natl Cancer Inst. 2015 Nov 27;108(2):
pubmed: 26615022
Eur Urol. 2017 Nov;72(5):665-674
pubmed: 28511883
Eur Urol. 2017 Jul;72(1):45-51
pubmed: 28162815
Cell Syst. 2015 Dec 23;1(6):417-425
pubmed: 26771021
Cancer Discov. 2012 May;2(5):401-4
pubmed: 22588877
Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21276-81
pubmed: 22123976
Oncotarget. 2014 Sep 15;5(17):7217-59
pubmed: 25277175
JAMA. 2012 Nov 14;308(18):1871-80
pubmed: 23162860
N Engl J Med. 1989 Jul 20;321(3):129-35
pubmed: 2664509
Science. 2005 Oct 14;310(5746):306-10
pubmed: 16224021
Neoplasia. 2014 Jan;16(1):14-20
pubmed: 24563616
Cell. 2015 Nov 5;163(4):1011-25
pubmed: 26544944
J Natl Cancer Inst. 2013 Dec 18;105(24):1881-90
pubmed: 24292212
J Urol. 2018 Jan;199(1):106-113
pubmed: 28728994
Sci Signal. 2013 Apr 02;6(269):pl1
pubmed: 23550210
Cancer Epidemiol Biomarkers Prev. 1997 Jun;6(6):443-50
pubmed: 9184779
Cancer Genet. 2014 Oct-Dec;207(10-12):474-88
pubmed: 25434580
N Engl J Med. 2015 Oct 29;373(18):1697-708
pubmed: 26510020
Mod Pathol. 2016 Jun;29(6):630-6
pubmed: 26939875
Urol Oncol. 2017 Aug;35(8):535
pubmed: 28623072
Cancer Cell. 2017 Mar 13;31(3):436-451
pubmed: 28292441
Eur J Cancer. 2014 Jun;50(9):1610-6
pubmed: 24703897

Auteurs

Habiba Elfandy (H)

Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Department of Pathology, National Cancer Institute, Cairo University, Cairo, Egypt.

Joshua Armenia (J)

Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.

Filippo Pederzoli (F)

Vita-Salute San Raffaele University, Milan, Italy.
ORCID: 0000-0003-3873-7465

Eli Pullman (E)

George Washington University, Washington, D.C.

Nelma Pertega-Gomes (N)

Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts.

Nikolaus Schultz (N)

Memorial Sloan Kettering Cancer Center, New York, New York.

Kartik Viswanathan (K)

Department of Pathology, Weill Cornell Medicine, New York, NY, USA.

Aram Vosoughi (A)

Department of Pathology, Weill Cornell Medicine, New York, NY, USA.
Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, New York.

Mirjam Blattner (M)

Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, New York.
Department of Urology, Weill Cornell Medicine, New York, New York.

Konrad H Stopsack (KH)

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
ORCID: 0000-0002-0722-1311

Giorgia Zadra (G)

Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Kathryn L Penney (KL)

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Juan Miguel Mosquera (JM)

Department of Pathology, Weill Cornell Medicine, New York, NY, USA.
Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, New York.

Svitlana Tyekucheva (S)

Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Department of Biostatistics, Harvard TH Chan School of Public Health, Boston, Massachusetts.
ORCID: 0000-0002-3119-6507

Lorelei A Mucci (LA)

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

Christopher Barbieri (C)

Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, New York.
Department of Urology, Weill Cornell Medicine, New York, New York.
ORCID: 0000-0002-0381-1947

Massimo Loda (M)

Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts. massimo_loda@dfci.harvard.edu.
Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
The Broad Institute, Cambridge, Massachusetts.

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Classifications MeSH

questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs épithéliales épidermoïdes et glandulaires › Carcinomes › Adénocarcinome › Genetic and Epigenetic Determinants of...
questionsmedicales.fr › Eucaryotes › Animaux › Genetic and Epigenetic Determinants of...
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Génétique › Génomique › Épigénomique › Genetic and Epigenetic Determinants of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Genetic and Epigenetic Determinants of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Genetic and Epigenetic Determinants of...
questionsmedicales.fr › Maladies urogénitales › Tumeurs de l'appareil urogénital › Tumeurs de l'appareil génital mâle › Tumeurs de la prostate › Genetic and Epigenetic Determinants of...