Massimo Loda

Affiliations

Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA.

Publications (69)

SARS-CoV-2 Viral Load Predicts Mortality in Patients with and without Cancer Who Are Hospitalized with COVID-19.

Cancer cell

Avec: Lars F Westblade , Gagandeep Brar , Laura C Pinheiro , Demetrios Paidoussis , Mangala Rajan , Peter Martin , Parag Goyal , Jorge L Sepulveda , Lisa Zhang , Gary George , Dakai Liu , Susan Whittier , Markus Plate , Catherine B Small , Jacob H Rand , Melissa M Cushing , Thomas J Walsh , Joseph Cooke , Monika M Safford , Massimo Loda , Michael J Satlin

Exploring a role for fatty acid synthase in prostate cancer cell migration.

Small GTPases

Avec: Mario De Piano , Valeria Manuelli , Giorgia Zadra , Massimo Loda , Gordon Muir , Ash Chandra , Jonathan Morris , Mieke Van Hemelrijck , Claire M Wells

Genetic ablation of FASN attenuates the invasive potential of prostate cancer driven by Pten loss.

The Journal of pathology

Avec: Débora C Bastos , Caroline F Ribeiro , Thomas Ahearn , Jéssica Nascimento , Hubert Pakula , John Clohessy , Lorelei Mucci , Thomas Roberts , Silvio M Zanata , Giorgia Zadra , Massimo Loda

Lipogenic signalling modulates prostate cancer cell adhesion and migration via modification of Rho GTPases.

Oncogene

Avec: Mario De Piano , Valeria Manuelli , Giorgia Zadra , Jonathan Otte , Per-Henrik D Edqvist , Fredrik Pontén , Salpie Nowinski , Athanasios Niaouris , Anita Grigoriadis , Massimo Loda , Mieke Van Hemelrijck , Claire M Wells

Routine Laboratory Blood Tests Predict SARS-CoV-2 Infection Using Machine Learning.

Clinical chemistry

Avec: He S Yang , Yu Hou , Ljiljana V Vasovic , Peter A D Steel , Amy Chadburn , Sabrina E Racine-Brzostek , Priya Velu , Melissa M Cushing , Massimo Loda , Rainu Kaushal , Zhen Zhao , Fei Wang

SARS-CoV-2 antibody characterization in emergency department, hospitalized and convalescent patients by two semi-quantitative immunoassays.

Clinica chimica acta; international journal of clinical chemistry

Avec: He S Yang , Sabrina E Racine-Brzostek , William T Lee , Danielle Hunt , Jim Yee , Zhengming Chen , Jeffrey Kubiak , Miguel Cantu , Layla Hatem , Elaine Zhong , Danielle D'Ambrosio , Amy Chadburn , Lars Westblade , Marshall Glesby , Massimo Loda , Melissa M Cushing , Zhen Zhao

Phase I study of the

Journal for immunotherapy of cancer

Avec: Chul Kim , Stephen V Liu , Deepa S Subramaniam , Tisdrey Torres , Massimo Loda , Giuseppe Esposito , Giuseppe Giaccone

The New York State SARS-CoV-2 Testing Consortium: Regional Communication in Response to the COVID-19 Pandemic.

Academic pathology

Avec: James M Crawford , Maria E Aguero-Rosenfeld , Ioannis Aifantis , Evan M Cadoff , Joan F Cangiarella , Carlos Cordon-Cardo , Melissa Cushing , Aldolfo Firpo-Betancourt , Amy S Fox , Yoko Furuya , Sean Hacking , Jeffrey Jhang , Debra G B Leonard , Jenny Libien , Massimo Loda , Damadora Rao Mendu , Mark J Mulligan , Michel R Nasr , Nicole D Pecora , Melissa S Pessin , Michael B Prystowsky , Lakshmi V Ramanathan , Kathleen R Rauch , Scott Riddell , Karen Roach , Kevin A Roth , Kenneth R Shroyer , Bruce R Smoller , Steven L Spitalnik , Eric D Spitzer , John E Tomaszewski , Susan Waltman , Loretta Willis , Zeynep Sumer-King

The Prostate Stromal Transcriptome in Aggressive and Lethal Prostate Cancer.

Molecular cancer research : MCR

Avec: Chaoran Ma , Yinglu Zhou , Giuseppe Nicolò Fanelli , Konrad H Stopsack , Michelangelo Fiorentino , Giorgia Zadra , Lorelei A Mucci , Massimo Loda , Svitlana Tyekucheva , Kathryn L Penney

Randomized Trial of Olaparib With or Without Cediranib for Metastatic Castration-Resistant Prostate Cancer: The Results From National Cancer Institute 9984.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Joseph W Kim , Rana R McKay , Marc R Radke , Shilin Zhao , Mary-Ellen Taplin , Nancy B Davis , Paul Monk , Leonard J Appleman , Primo N Lara , Ulka N Vaishampayan , Jingsong Zhang , Asit K Paul , Glenn Bubley , Eliezer M Van Allen , Serhan Unlu , Ying Huang , Massimo Loda , Geoffrey I Shapiro , Peter M Glazer , Patricia M LoRusso , S Percy Ivy , Yu Shyr , Elizabeth M Swisher , Daniel P Petrylak

Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer.

Molecular cancer research : MCR

Avec: Xueliang Gao , Yubao Wang , Caroline F Ribeiro , Cherubin Manokaran , Hyeyoun Chang , Thanh Von , Silvia Rodrigues , Onur Cizmecioglu , Shidong Jia , Manav Korpal , Joshua M Korn , Zhigang Wang , Fabienne Schmit , Lan Jiang , Raymond Pagliarini , Yi Yang , Isha Sethi , Sabina Signoretti , Guo-Cheng Yuan , Massimo Loda , Jean J Zhao , Thomas M Roberts

Germline Genetic Variants Associated with Somatic TMPRSS2:ERG Fusion Status in Prostate Cancer: A Genome-Wide Association Study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Avec: Chaoran Ma , Xiaoyu Wang , James Y Dai , Constance Turman , Peter Kraft , Konrad H Stopsack , Massimo Loda , Andreas Pettersson , Lorelei A Mucci , Janet L Stanford , Kathryn L Penney

NSD2 maintains lineage plasticity and castration-resistance in neuroendocrine prostate cancer.

bioRxiv : the preprint server for biology

Avec: Jia J Li , Alessandro Vasciaveo , Dimitrios Karagiannis , Zhen Sun , Xiao Chen , Fabio Socciarelli , Ziv Frankenstein , Min Zou , Tania Pannellini , Yu Chen , Kevin Gardner , Brian D Robinson , Johann de Bono , Cory Abate-Shen , Mark A Rubin , Massimo Loda , Charles L Sawyers , Andrea Califano , Chao Lu , Michael M Shen

Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention.

Advanced drug delivery reviews

Avec: Lisa M Butler , Ylenia Perone , Jonas Dehairs , Leslie E Lupien , Vincent de Laat , Ali Talebi , Massimo Loda , William B Kinlaw , Johannes V Swinnen

Tumor protein expression of the DNA repair gene BRCA1 and lethal prostate cancer.

Carcinogenesis

Avec: Konrad H Stopsack , Travis Gerke , Piotr Zareba , Andreas Pettersson , Dipanjan Chowdhury , Ericka M Ebot , Richard Flavin , Stephen Finn , Philip W Kantoff , Meir J Stampfer , Massimo Loda , Michelangelo Fiorentino , Lorelei A Mucci

Comparison of Two High-Throughput Reverse Transcription-PCR Systems for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2.

Journal of clinical microbiology

Avec: Arryn R Craney , Priya D Velu , Michael J Satlin , Kathy A Fauntleroy , Katrina Callan , Amy Robertson , Marisa La Spina , Beryl Lei , Anqi Chen , Tricia Alston , Anna Rozman , Massimo Loda , Hanna Rennert , Melissa Cushing , Lars F Westblade

Targeting potential drivers of COVID-19: Neutrophil extracellular traps.

The Journal of experimental medicine

Avec: Betsy J Barnes , Jose M Adrover , Amelia Baxter-Stoltzfus , Alain Borczuk , Jonathan Cools-Lartigue , James M Crawford , Juliane Daßler-Plenker , Philippe Guerci , Caroline Huynh , Jason S Knight , Massimo Loda , Mark R Looney , Florencia McAllister , Roni Rayes , Stephane Renaud , Simon Rousseau , Steven Salvatore , Robert E Schwartz , Jonathan D Spicer , Christian C Yost , Andrew Weber , Yu Zuo , Mikala Egeblad

Family history of prostate cancer and the incidence of ERG- and phosphatase and tensin homolog-defined prostate cancer.

International journal of cancer

Avec: Dana Hashim , Amparo G Gonzalez-Feliciano , Thomas U Ahearn , Andreas Pettersson , Lauren Barber , Claire H Pernar , Ericka M Ebot , Masis Isikbay , Stephen P Finn , Edward L Giovannucci , Rosina T Lis , Massimo Loda , Giovanni Parmigiani , Tamara Lotan , Philip W Kantoff , Lorelei A Mucci , Rebecca E Graff

Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps.

bioRxiv : the preprint server for biology

Avec: Jiwoon Park , Jonathan Foox , Tyler Hether , David Danko , Sarah Warren , Youngmi Kim , Jason Reeves , Daniel J Butler , Christopher Mozsary , Joel Rosiene , Alon Shaiber , Ebrahim Afshinnekoo , Matthew MacKay , Yaron Bram , Vasuretha Chandar , Heather Geiger , Arryn Craney , Priya Velu , Ari M Melnick , Iman Hajirasouliha , Afshin Beheshti , Deanne Taylor , Amanda Saravia-Butler , Urminder Singh , Eve Syrkin Wurtele , Jonathan Schisler , Samantha Fennessey , André Corvelo , Michael C Zody , Soren Germer , Steven Salvatore , Shawn Levy , Shixiu Wu , Nicholas Tatonetti , Sagi Shapira , Mirella Salvatore , Massimo Loda , Lars F Westblade , Melissa Cushing , Hanna Rennert , Alison J Kriegel , Olivier Elemento , Marcin Imielinski , Alain C Borczuk , Cem Meydan , Robert E Schwartz , Christopher E Mason

Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions.

Nature communications

Avec: Daniel Butler , Christopher Mozsary , Cem Meydan , Jonathan Foox , Joel Rosiene , Alon Shaiber , David Danko , Ebrahim Afshinnekoo , Matthew MacKay , Fritz J Sedlazeck , Nikolay A Ivanov , Maria Sierra , Diana Pohle , Michael Zietz , Undina Gisladottir , Vijendra Ramlall , Evan T Sholle , Edward J Schenck , Craig D Westover , Ciaran Hassan , Krista Ryon , Benjamin Young , Chandrima Bhattacharya , Dianna L Ng , Andrea C Granados , Yale A Santos , Venice Servellita , Scot Federman , Phyllis Ruggiero , Arkarachai Fungtammasan , Chen-Shan Chin , Nathaniel M Pearson , Bradley W Langhorst , Nathan A Tanner , Youngmi Kim , Jason W Reeves , Tyler D Hether , Sarah E Warren , Michael Bailey , Justyna Gawrys , Dmitry Meleshko , Dong Xu , Mara Couto-Rodriguez , Dorottya Nagy-Szakal , Joseph Barrows , Heather Wells , Niamh B O'Hara , Jeffrey A Rosenfeld , Ying Chen , Peter A D Steel , Amos J Shemesh , Jenny Xiang , Jean Thierry-Mieg , Danielle Thierry-Mieg , Angelika Iftner , Daniela Bezdan , Elizabeth Sanchez , Thomas R Campion , John Sipley , Lin Cong , Arryn Craney , Priya Velu , Ari M Melnick , Sagi Shapira , Iman Hajirasouliha , Alain Borczuk , Thomas Iftner , Mirella Salvatore , Massimo Loda , Lars F Westblade , Melissa Cushing , Shixiu Wu , Shawn Levy , Charles Chiu , Robert E Schwartz , Nicholas Tatonetti , Hanna Rennert , Marcin Imielinski , Christopher E Mason

EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer.

Nature cancer

Avec: Katherine L Morel , Anjali V Sheahan , Deborah L Burkhart , Sylvan C Baca , Nadia Boufaied , Yin Liu , Xintao Qiu , Israel Cañadas , Kevin Roehle , Max Heckler , Carla Calagua , Huihui Ye , Constantia Pantelidou , Phillip Galbo , Sukanya Panja , Antonina Mitrofanova , Scott Wilkinson , Nichelle C Whitlock , Shana Y Trostel , Anis A Hamid , Adam S Kibel , David A Barbie , Atish D Choudhury , Mark M Pomerantz , Christopher J Sweeney , Henry W Long , David J Einstein , Geoffrey I Shapiro , Stephanie K Dougan , Adam G Sowalsky , Housheng Hansen He , Matthew L Freedman , Steven P Balk , Massimo Loda , David P Labbé , Brian M Olson , Leigh Ellis

Association of Prediagnostic Blood Metabolomics with Prostate Cancer Defined by ERG or PTEN Molecular Subtypes.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Avec: Xiaoshuang Feng , Cindy Ke Zhou , Clary B Clish , Kathryn M Wilson , Claire H Pernar , Barbra A Dickerman , Massimo Loda , Stephen P Finn , Kathryn L Penney , Daniel R Schmidt , Matthew G Vander Heiden , Edward L Giovannucci , Ericka M Ebot , Lorelei A Mucci

Extent, impact, and mitigation of batch effects in tumor biomarker studies using tissue microarrays.

eLife

Avec: Konrad H Stopsack , Svitlana Tyekucheva , Molin Wang , Travis A Gerke , J Bailey Vaselkiv , Kathryn L Penney , Philip W Kantoff , Stephen P Finn , Michelangelo Fiorentino , Massimo Loda , Tamara L Lotan , Giovanni Parmigiani , Lorelei A Mucci

Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma.

Cancer research

Avec: Shawn M Davidson , Daniel R Schmidt , Julia E Heyman , James P O'Brien , Amy C Liu , William J Israelsen , Talya L Dayton , Raghav Sehgal , Roderick T Bronson , Elizaveta Freinkman , Howard H Mak , Giuseppe Nicolò Fanelli , Scott Malstrom , Gary Bellinger , Arkaitz Carracedo , Pier Paolo Pandolfi , Kevin D Courtney , Abhishek Jha , Ronald A DePinho , James W Horner , Craig J Thomas , Lewis C Cantley , Massimo Loda , Matthew G Vander Heiden

Castration-resistant prostate cancer cells are dependent on the high activity of CDK7.

Journal of cancer research and clinical oncology

Avec: Satu Pallasaho , Aishwarya Gondane , Anni Kuivalainen , Samuel Girmay , Siver Moestue , Massimo Loda , Harri M Itkonen

SPOP Mutations Target STING1 Signaling in Prostate Cancer and Create Therapeutic Vulnerabilities to PARP Inhibitor-Induced Growth Suppression.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Chuandong Geng , Man-Chao Zhang , Ganiraju C Manyam , Jody V Vykoukal , Johannes F Fahrmann , Shan Peng , Cheng Wu , Sanghee Park , Shakuntala Kondraganti , Daoqi Wang , Brian D Robinson , Massimo Loda , Christopher E Barbieri , Timothy A Yap , Paul G Corn , Samir Hanash , Bradley M Broom , Patrick G Pilié , Timothy C Thompson

Linking African ancestral substructure to prostate cancer health disparities.

Scientific reports

Avec: Kazzem Gheybi , Naledi Mmekwa , Maphuti Tebogo Lebelo , Sean M Patrick , Raymond Campbell , Mukudeni Nenzhelele , Pamela X Y Soh , Muvhulawa Obida , Massimo Loda , Joyce Shirindi , Eboneé N Butler , Shingai B A Mutambirwa , M S Riana Bornman , Vanessa M Hayes

When fat goes down, prostate cancer is on the ropes.

Molecular & cellular oncology

Avec: Giorgia Zadra , Massimo Loda

CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer.

Cell reports

Avec: Justin H Hwang , Ji-Heui Seo , Michael L Beshiri , Stephanie Wankowicz , David Liu , Alexander Cheung , Ji Li , Xintao Qiu , Andrew L Hong , Ginevra Botta , Lior Golumb , Camden Richter , Jonathan So , Gabriel J Sandoval , Andrew O Giacomelli , Seav Huong Ly , Celine Han , Chao Dai , Hubert Pakula , Anjali Sheahan , Federica Piccioni , Ole Gjoerup , Massimo Loda , Adam G Sowalsky , Leigh Ellis , Henry Long , David E Root , Kathleen Kelly , Eliezer M Van Allen , Matthew L Freedman , Atish D Choudhury , William C Hahn

A Prospective Study of Intraprostatic Inflammation, Focal Atrophy, and Progression to Lethal Prostate Cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Avec: Yiwen Zhang , Cindy Ke Zhou , Emily M Rencsok , Katja Fall , Tamara L Lotan , Massimo Loda , Francesca Giunchi , Elizabeth A Platz , Angelo M De Marzo , Lorelei A Mucci , Michelangelo Fiorentino , Ericka M Ebot

Molecular Characterization of Prostate Cancer with Associated Gleason Score Using Mass Spectrometry Imaging.

Molecular cancer research : MCR

Avec: Elizabeth C Randall , Giorgia Zadra , Paolo Chetta , Begona G C Lopez , Sudeepa Syamala , Sankha S Basu , Jeffrey N Agar , Massimo Loda , Clare M Tempany , Fiona M Fennessy , Nathalie Y R Agar

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Giorgia Zadra , Caroline F Ribeiro , Paolo Chetta , Yeung Ho , Stefano Cacciatore , Xueliang Gao , Sudeepa Syamala , Clyde Bango , Cornelia Photopoulos , Ying Huang , Svitlana Tyekucheva , Debora C Bastos , Jeremy Tchaicha , Brian Lawney , Takuma Uo , Laura D'Anello , Alfredo Csibi , Radha Kalekar , Benjamin Larimer , Leigh Ellis , Lisa M Butler , Colm Morrissey , Karen McGovern , Vito J Palombella , Jeffery L Kutok , Umar Mahmood , Silvano Bosari , Julian Adams , Stephane Peluso , Scott M Dehm , Stephen R Plymate , Massimo Loda

Evidence that EZH2 Deregulation is an Actionable Therapeutic Target for Prevention of Prostate Cancer.

Cancer prevention research (Philadelphia, Pa.)

Avec: Deborah L Burkhart , Katherine L Morel , Kristine M Wadosky , David P Labbé , Phillip M Galbo , Zafardjan Dalimov , Bo Xu , Massimo Loda , Leigh Ellis

PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis.

Molecular cell

Avec: Juan F Linares , Xiao Zhang , Anxo Martinez-Ordoñez , Angeles Duran , Hiroto Kinoshita , Hiroaki Kasashima , Naoko Nakanishi , Yuki Nakanishi , Ryan Carelli , Luca Cappelli , Esperanza Arias , Masakazu Yashiro , Masaichi Ohira , Sanjay Patel , Giorgio Inghirami , Massimo Loda , Ana Maria Cuervo , Maria T Diaz-Meco , Jorge Moscat

Avec: Dominik Awad , Pham Hong Anh Cao , Thomas L Pulliam , Meredith Spradlin , Elavarasan Subramani , Tristen V Tellman , Caroline F Ribeiro , Riccardo Muzzioli , Brittany E Jewell , Hubert Pakula , Jeffrey J Ackroyd , Mollianne M Murray , Jenny J Han , Mei Leng , Antrix Jain , Badrajee Piyarathna , JIngjing Liu , Xingzhi Song , Jianhua Zhang , Albert R Klekers , Justin M Drake , Michael M Ittmann , Cristian Coarfa , David Piwnica-Worms , Mary C Farach-Carson , Massimo Loda , Livia S Eberlin , Daniel E Frigo

Federated benchmarking of medical artificial intelligence with MedPerf.

Nature machine intelligence

Avec: Alexandros Karargyris , Renato Umeton , Micah J Sheller , Alejandro Aristizabal , Johnu George , Anna Wuest , Sarthak Pati , Hasan Kassem , Maximilian Zenk , Ujjwal Baid , Prakash Narayana Moorthy , Alexander Chowdhury , Junyi Guo , Sahil Nalawade , Jacob Rosenthal , David Kanter , Maria Xenochristou , Daniel J Beutel , Verena Chung , Timothy Bergquist , James Eddy , Abubakar Abid , Lewis Tunstall , Omar Sanseviero , Dimitrios Dimitriadis , Yiming Qian , Xinxing Xu , Yong Liu , Rick Siow Mong Goh , Srini Bala , Victor Bittorf , Sreekar Reddy Puchala , Biagio Ricciuti , Soujanya Samineni , Eshna Sengupta , Akshay Chaudhari , Cody Coleman , Bala Desinghu , Gregory Diamos , Debo Dutta , Diane Feddema , Grigori Fursin , Xinyuan Huang , Satyananda Kashyap , Nicholas Lane , Indranil Mallick , Auteur inconnu , Auteur inconnu , Auteur inconnu , Pietro Mascagni , Virendra Mehta , Cassiano Ferro Moraes , Vivek Natarajan , Nikola Nikolov , Nicolas Padoy , Gennady Pekhimenko , Vijay Janapa Reddi , G Anthony Reina , Pablo Ribalta , Abhishek Singh , Jayaraman J Thiagarajan , Jacob Albrecht , Thomas Wolf , Geralyn Miller , Huazhu Fu , Prashant Shah , Daguang Xu , Poonam Yadav , David Talby , Mark M Awad , Jeremy P Howard , Michael Rosenthal , Luigi Marchionni , Massimo Loda , Jason M Johnson , Spyridon Bakas , Peter Mattson

Transcriptomes of Prostate Cancer with TMPRSS2:ERG and Other ETS Fusions.

Molecular cancer research : MCR

Avec: Konrad H Stopsack , Xiaofeng A Su , J Bailey Vaselkiv , Rebecca E Graff , Ericka M Ebot , Andreas Pettersson , Rosina T Lis , Michelangelo Fiorentino , Massimo Loda , Kathryn L Penney , Tamara L Lotan , Lorelei A Mucci

A MIR17HG-derived long noncoding RNA provides an essential chromatin scaffold for protein interaction and myeloma growth.

Blood

Avec: Eugenio Morelli , Mariateresa Fulciniti , Mehmet K Samur , Caroline F Ribeiro , Leon Wert-Lamas , Jon E Henninger , Annamaria Gullà , Anil Aktas-Samur , Katia Todoerti , Srikanth Talluri , Woojun D Park , Cinzia Federico , Francesca Scionti , Nicola Amodio , Giada Bianchi , Megan Johnstone , Na Liu , Doriana Gramegna , Domenico Maisano , Nicola A Russo , Charles Lin , Yu-Tzu Tai , Antonino Neri , Dharminder Chauhan , Teru Hideshima , Masood A Shammas , Pierfrancesco Tassone , Sergei Gryaznov , Richard A Young , Kenneth C Anderson , Carl D Novina , Massimo Loda , Nikhil C Munshi

Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions.

bioRxiv : the preprint server for biology

Avec: Daniel J Butler , Christopher Mozsary , Cem Meydan , David Danko , Jonathan Foox , Joel Rosiene , Alon Shaiber , Ebrahim Afshinnekoo , Matthew MacKay , Fritz J Sedlazeck , Nikolay A Ivanov , Maria Sierra , Diana Pohle , Michael Zietz , Undina Gisladottir , Vijendra Ramlall , Craig D Westover , Krista Ryon , Benjamin Young , Chandrima Bhattacharya , Phyllis Ruggiero , Bradley W Langhorst , Nathan Tanner , Justyna Gawrys , Dmitry Meleshko , Dong Xu , Peter A D Steel , Amos J Shemesh , Jenny Xiang , Jean Thierry-Mieg , Danielle Thierry-Mieg , Robert E Schwartz , Angelika Iftner , Daniela Bezdan , John Sipley , Lin Cong , Arryn Craney , Priya Velu , Ari M Melnick , Iman Hajirasouliha , Stacy M Horner , Thomas Iftner , Mirella Salvatore , Massimo Loda , Lars F Westblade , Melissa Cushing , Shawn Levy , Shixiu Wu , Nicholas Tatonetti , Marcin Imielinski , Hanna Rennert , Christopher E Mason

Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome.

Blood

Avec: Elizabeth A Middleton , Xue-Yan He , Frederik Denorme , Robert A Campbell , David Ng , Steven P Salvatore , Maria Mostyka , Amelia Baxter-Stoltzfus , Alain C Borczuk , Massimo Loda , Mark J Cody , Bhanu Kanth Manne , Irina Portier , Estelle S Harris , Aaron C Petrey , Ellen J Beswick , Aleah F Caulin , Anthony Iovino , Lisa M Abegglen , Andrew S Weyrich , Matthew T Rondina , Mikala Egeblad , Joshua D Schiffman , Christian Con Yost

High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program.

Nature communications

Avec: David P Labbé , Giorgia Zadra , Meng Yang , Jaime M Reyes , Charles Y Lin , Stefano Cacciatore , Ericka M Ebot , Amanda L Creech , Francesca Giunchi , Michelangelo Fiorentino , Habiba Elfandy , Sudeepa Syamala , Edward D Karoly , Mohammed Alshalalfa , Nicholas Erho , Ashley Ross , Edward M Schaeffer , Ewan A Gibb , Mandeep Takhar , Robert B Den , Jonathan Lehrer , R Jeffrey Karnes , Stephen J Freedland , Elai Davicioni , Daniel E Spratt , Leigh Ellis , Jacob D Jaffe , Anthony V DʼAmico , Philip W Kantoff , James E Bradner , Lorelei A Mucci , Jorge E Chavarro , Massimo Loda , Myles Brown

Statin Use Is Associated with Lower Risk of PTEN-Null and Lethal Prostate Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Emma H Allott , Ericka M Ebot , Konrad H Stopsack , Amparo G Gonzalez-Feliciano , Sarah C Markt , Kathryn M Wilson , Thomas U Ahearn , Travis A Gerke , Mary K Downer , Jennifer R Rider , Stephen J Freedland , Tamara L Lotan , Philip W Kantoff , Elizabeth A Platz , Massimo Loda , Meir J Stampfer , Edward Giovannucci , Christopher J Sweeney , Stephen P Finn , Lorelei A Mucci

The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Himisha Beltran , Andrew Hruszkewycz , Howard I Scher , Jeffrey Hildesheim , Jennifer Isaacs , Evan Y Yu , Kathleen Kelly , Daniel Lin , Adam Dicker , Julia Arnold , Toby Hecht , Max Wicha , Rosalie Sears , David Rowley , Richard White , James L Gulley , John Lee , Maria Diaz Meco , Eric J Small , Michael Shen , Karen Knudsen , David W Goodrich , Tamara Lotan , Amina Zoubeidi , Charles L Sawyers , Charles M Rudin , Massimo Loda , Timothy Thompson , Mark A Rubin , Abdul Tawab-Amiri , William Dahut , Peter S Nelson

Genomic correlates of clinical outcome in advanced prostate cancer.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Wassim Abida , Joanna Cyrta , Glenn Heller , Davide Prandi , Joshua Armenia , Ilsa Coleman , Marcin Cieslik , Matteo Benelli , Dan Robinson , Eliezer M Van Allen , Andrea Sboner , Tarcisio Fedrizzi , Juan Miguel Mosquera , Brian D Robinson , Navonil De Sarkar , Lakshmi P Kunju , Scott Tomlins , Yi Mi Wu , Daniel Nava Rodrigues , Massimo Loda , Anuradha Gopalan , Victor E Reuter , Colin C Pritchard , Joaquin Mateo , Diletta Bianchini , Susana Miranda , Suzanne Carreira , Pasquale Rescigno , Julie Filipenko , Jacob Vinson , Robert B Montgomery , Himisha Beltran , Elisabeth I Heath , Howard I Scher , Philip W Kantoff , Mary-Ellen Taplin , Nikolaus Schultz , Johann S deBono , Francesca Demichelis , Peter S Nelson , Mark A Rubin , Arul M Chinnaiyan , Charles L Sawyers

Avec: Habiba Elfandy , Joshua Armenia , Filippo Pederzoli , Eli Pullman , Nelma Pertega-Gomes , Nikolaus Schultz , Kartik Viswanathan , Aram Vosoughi , Mirjam Blattner , Konrad H Stopsack , Giorgia Zadra , Kathryn L Penney , Juan Miguel Mosquera , Svitlana Tyekucheva , Lorelei A Mucci , Christopher Barbieri , Massimo Loda

Multiplex Immunofluorescence in Formalin-Fixed Paraffin-Embedded Tumor Tissue to Identify Single-Cell-Level PI3K Pathway Activation.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Konrad H Stopsack , Ying Huang , Svitlana Tyekucheva , Travis A Gerke , Clyde Bango , Habiba Elfandy , Michaela Bowden , Kathryn L Penney , Thomas M Roberts , Giovanni Parmigiani , Philip W Kantoff , Lorelei A Mucci , Massimo Loda

Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum.

Molecular cancer research : MCR

Avec: Kathryn L Penney , Svitlana Tyekucheva , Jacob Rosenthal , Habiba El Fandy , Ryan Carelli , Stephanie Borgstein , Giorgia Zadra , Giuseppe Nicolò Fanelli , Lavinia Stefanizzi , Francesca Giunchi , Mark Pomerantz , Samuel Peisch , Hannah Coulson , Rosina Lis , Adam S Kibel , Michelangelo Fiorentino , Renato Umeton , Massimo Loda

Rapid Implementation of Severe Acute Respiratory Syndrome Coronavirus 2 Emergency Use Authorization RT-PCR Testing and Experience at an Academic Medical Institution.

The Journal of molecular diagnostics : JMD

Avec: Priya Velu , Arryn Craney , Phyllis Ruggiero , John Sipley , Lin Cong , Erika M Hissong , Massimo Loda , Lars F Westblade , Melissa Cushing , Hanna Rennert

Avec: Xintao Qiu , Nadia Boufaied , Tarek Hallal , Avery Feit , Anna de Polo , Adrienne M Luoma , Walaa Alahmadi , Janie Larocque , Giorgia Zadra , Yingtian Xie , Shengqing Gu , Qin Tang , Yi Zhang , Sudeepa Syamala , Ji-Heui Seo , Connor Bell , Edward O'Connor , Yang Liu , Edward M Schaeffer , R Jeffrey Karnes , Sheila Weinmann , Elai Davicioni , Colm Morrissey , Paloma Cejas , Leigh Ellis , Massimo Loda , Kai W Wucherpfennig , Mark M Pomerantz , Daniel E Spratt , Eva Corey , Matthew L Freedman , X Shirley Liu , Myles Brown , Henry W Long , David P Labbé

Rare Germline Variants Are Associated with Rapid Biochemical Recurrence After Radical Prostate Cancer Treatment: A Pan Prostate Cancer Group Study.

European urology

Avec: Daniel Burns , Ezequiel Anokian , Edward J Saunders , Robert G Bristow , Michael Fraser , Jüri Reimand , Thorsten Schlomm , Guido Sauter , Benedikt Brors , Jan Korbel , Joachim Weischenfeldt , Sebastian M Waszak , Niall M Corcoran , Chol-Hee Jung , Bernard J Pope , Chris M Hovens , Géraldine Cancel-Tassin , Olivier Cussenot , Massimo Loda , Chris Sander , Vanessa M Hayes , Karina Dalsgaard Sorensen , Yong-Jie Lu , Freddie C Hamdy , Christopher S Foster , Vincent Gnanapragasam , Adam Butler , Andy G Lynch , Charlie E Massie , Auteur inconnu , Dan J Woodcock , Colin S Cooper , David C Wedge , Daniel S Brewer , Zsofia Kote-Jarai , Rosalind A Eeles

Fatty acid synthase as a potential new therapeutic target for cervical cancer.

Anais da Academia Brasileira de Ciencias

Avec: Jéssica Nascimento , Camila Mariot , Débora R B Vianna , Lúcia M Kliemann , Paula S Chaves , Massimo Loda , Andréia Buffon , Ruy C R Beck , Diogo A Pilger

Distinct mesenchymal cell states mediate prostate cancer progression.

Nature communications

Avec: Hubert Pakula , Mohamed Omar , Ryan Carelli , Filippo Pederzoli , Giuseppe Nicolò Fanelli , Tania Pannellini , Fabio Socciarelli , Lucie Van Emmenis , Silvia Rodrigues , Caroline Fidalgo-Ribeiro , Pier Vitale Nuzzo , Nicholas J Brady , Wikum Dinalankara , Madhavi Jere , Itzel Valencia , Christopher Saladino , Jason Stone , Caitlin Unkenholz , Richard Garner , Mohammad K Alexanderani , Francesca Khani , Francisca Nunes de Almeida , Cory Abate-Shen , Matthew B Greenblatt , David S Rickman , Christopher E Barbieri , Brian D Robinson , Luigi Marchionni , Massimo Loda

The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response.

Cancer research

Avec: Jacob E Berchuck , Elio Adib , Sarah Abou Alaiwi , Amit K Dash , Jin Na Shin , Dallin Lowder , Collin McColl , Patricia Castro , Ryan Carelli , Elisa Benedetti , Jenny Deng , Matthew Robertson , Sylvan C Baca , Connor Bell , Heather M McClure , Talal El Zarif , Matthew P Davidsohn , Gitanjali Lakshminarayanan , Kinza Rizwan , Darlene G Skapura , Sandra L Grimm , Christel M Davis , Erik A Ehli , Kaitlin M Kelleher , Ji-Heui Seo , Nicholas Mitsiades , Cristian Coarfa , Mark M Pomerantz , Massimo Loda , Michael Ittmann , Matthew L Freedman , Salma Kaochar

Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer.

Science translational medicine

Avec: Mengdie Wang , Christi A Wisniewski , Choua Xiong , Peter Chhoy , Hira Lal Goel , Ayush Kumar , Lihua Julie Zhu , Rui Li , Pamela A St Louis , Lindsay M Ferreira , Hubert Pakula , Zhiwen Xu , Massimo Loda , Zhong Jiang , Michael A Brehm , Arthur M Mercurio

Suppression of tumor cell lactate-generating signaling pathways eradicates murine PTEN/p53-deficient aggressive-variant prostate cancer via macrophage phagocytosis.

bioRxiv : the preprint server for biology

Avec: Kiranj Chaudagar , Hanna M Hieromnimon , Anne Kelley , Brian Labadie , Jordan Shafran , Srikrishnan Rameshbabu , Catherine Drovetsky , Kaela Bynoe , Ani Solanki , Erica Markiewicz , Xiaobing Fan , Massimo Loda , Akash Patnaik

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