Manav Korpal

Affiliations

Oncology Disease Area, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.

ORCID: 0009-0002-0288-8851

Publications (10)

Generating a Murine PTEN Null Cell Line to Discover the Key Role of p110β-PAK1 in Castration-Resistant Prostate Cancer Invasion.

Molecular cancer research : MCR

Avec: Haizhen Wang , Yu Zhou , Chen Chu , Jialing Xiao , Shanshan Zheng , Manav Korpal , Joshua M Korn , Tiffany Penaloza , Richard R Drake , Wenjian Gan , Xueliang Gao

Author Correction: Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer.

Nature communications

Avec: Manav Korpal , Xiaoling Puyang , Zhenhua Jeremy Wu , Roland Seiler , Craig Furman , Htoo Zarni Oo , Michael Seiler , Sean Irwin , Vanitha Subramanian , Jaya Julie Joshi , Chris K Wang , Victoria Rimkunas , Davide Tortora , Hua Yang , Namita Kumar , Galina Kuznetsov , Mark Matijevic , Jesse Chow , Pavan Kumar , Jian Zou , Jacob Feala , Laura Corson , Ryan Henry , Anand Selvaraj , Allison Davis , Kristjan Bloudoff , James Douglas , Bernhard Kiss , Morgan Roberts , Ladan Fazli , Peter C Black , Peter Fekkes , Peter G Smith , Markus Warmuth , Lihua Yu , Ming-Hong Hao , Nicholas Larsen , Mads Daugaard , Ping Zhu

Estrogen Receptor Covalent Antagonists: The Best Is Yet to Come.

Cancer research

Avec: Craig Furman , Ming-Hong Hao , Sudeep Prajapati , Dominic Reynolds , Victoria Rimkunas , Guo Z Zheng , Ping Zhu , Manav Korpal

Covalent ERα Antagonist H3B-6545 Demonstrates Encouraging Preclinical Activity in Therapy-Resistant Breast Cancer.

Molecular cancer therapeutics

Avec: Craig Furman , Xiaoling Puyang , Zhaojie Zhang , Zhenhua J Wu , Deepti Banka , Kiran B Aithal , Lee A Albacker , Ming-Hong Hao , Sean Irwin , Amy Kim , Meagan Montesion , Alyssa D Moriarty , Karthikeyan Murugesan , Tuong-Vi Nguyen , Victoria Rimkunas , Tarek Sahmoud , Michael J Wick , Shihua Yao , Xun Zhang , Hao Zeng , Frédéric H Vaillancourt , David M Bolduc , Nicholas Larsen , Guo Zhu Zheng , Sudeep Prajapati , Ping Zhu , Manav Korpal

Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer.

Molecular cancer research : MCR

Avec: Xueliang Gao , Yubao Wang , Caroline F Ribeiro , Cherubin Manokaran , Hyeyoun Chang , Thanh Von , Silvia Rodrigues , Onur Cizmecioglu , Shidong Jia , Manav Korpal , Joshua M Korn , Zhigang Wang , Fabienne Schmit , Lan Jiang , Raymond Pagliarini , Yi Yang , Isha Sethi , Sabina Signoretti , Guo-Cheng Yuan , Massimo Loda , Jean J Zhao , Thomas M Roberts

Identification of 2-Sulfonyl/Sulfonamide Pyrimidines as Covalent Inhibitors of WRN Using a Multiplexed High-Throughput Screening Assay.

Biochemistry

Avec: Mackenzie J Parker , Hyelee Lee , Shihua Yao , Sean Irwin , Sunil Hwang , Kylie Belanger , Sofia Woo de Mare , Richard Surgenor , Lu Yan , Patricia Gee , Shravan Morla , Xiaoling Puyang , Peng Hsiao , Hao Zeng , Ping Zhu , Manav Korpal , Paul Dransfield , David M Bolduc , Nicholas A Larsen

Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERα covalent antagonist (SERCA).

Cancer chemotherapy and pharmacology

Avec: Nathalie Rioux , Sherri Smith , Manav Korpal , Morgan O'Shea , Sudeep Prajapati , Guo Zhu Zheng , Markus Warmuth , Peter G Smith

Comparative study between P- POSSUM and Apache II scores in predicting outcomes of perforation peritonitis: Prospective observational cohort study.

International journal of surgery (London, England)

Avec: Raghav Yelamanchi , Nikhil Gupta , C K Durga , Manit Korpal

Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPARγ by inverse agonists.

The Journal of biological chemistry

Avec: Sean Irwin , Craig Karr , Craig Furman , Jennifer Tsai , Patricia Gee , Deepti Banka , Ardian S Wibowo , Alexey A Dementiev , Morgan O'Shea , Joyce Yang , Jason Lowe , Lorna Mitchell , Sabine Ruppel , Peter Fekkes , Ping Zhu , Manav Korpal , Nicholas A Larsen

Detection of circulating tumor cells by means of machine learning using Smart-Seq2 sequencing.

Scientific reports

Avec: Krzysztof Pastuszak , Michał Sieczczyński , Marta Dzięgielewska , Rafał Wolniak , Agata Drewnowska , Marcel Korpal , Laura Zembrzuska , Anna Supernat , Anna J Żaczek

Réseau de co-auteurs

Ping Zhu 5 collaborations

Craig Furman 4 collaborations

Sean Irwin 4 collaborations

Xiaoling Puyang 3 collaborations

Victoria Rimkunas 3 collaborations

Ming-Hong Hao 3 collaborations

Sudeep Prajapati 3 collaborations

Joshua M Korn 2 collaborations

Xueliang Gao 2 collaborations

Peter Fekkes 2 collaborations

Peter G Smith 2 collaborations

Markus Warmuth 2 collaborations

Nicholas Larsen 2 collaborations

Deepti Banka 2 collaborations

Shihua Yao 2 collaborations

Hao Zeng 2 collaborations

David M Bolduc 2 collaborations

Guo Zhu Zheng 2 collaborations

Patricia Gee 2 collaborations

Nicholas A Larsen 2 collaborations

Morgan O'Shea 2 collaborations

Haizhen Wang 1 collaboration

Yu Zhou 1 collaboration

Chen Chu 1 collaboration

Jialing Xiao 1 collaboration

Shanshan Zheng 1 collaboration

Tiffany Penaloza 1 collaboration

Richard R Drake 1 collaboration

Wenjian Gan 1 collaboration

Zhenhua Jeremy Wu 1 collaboration

Roland Seiler 1 collaboration

Htoo Zarni Oo 1 collaboration

Michael Seiler 1 collaboration

Vanitha Subramanian 1 collaboration

Jaya Julie Joshi 1 collaboration

Chris K Wang 1 collaboration

Davide Tortora 1 collaboration

Hua Yang 1 collaboration

Namita Kumar 1 collaboration

Galina Kuznetsov 1 collaboration

Mark Matijevic 1 collaboration

Jesse Chow 1 collaboration

Pavan Kumar 1 collaboration

Jian Zou 1 collaboration

Jacob Feala 1 collaboration

Laura Corson 1 collaboration

Ryan Henry 1 collaboration

Anand Selvaraj 1 collaboration

Allison Davis 1 collaboration

Kristjan Bloudoff 1 collaboration

James Douglas 1 collaboration

Bernhard Kiss 1 collaboration

Morgan Roberts 1 collaboration

Ladan Fazli 1 collaboration

Peter C Black 1 collaboration

Lihua Yu 1 collaboration

Mads Daugaard 1 collaboration

Dominic Reynolds 1 collaboration

Guo Z Zheng 1 collaboration

Zhaojie Zhang 1 collaboration

Zhenhua J Wu 1 collaboration

Kiran B Aithal 1 collaboration

Lee A Albacker 1 collaboration

Amy Kim 1 collaboration

Meagan Montesion 1 collaboration

Alyssa D Moriarty 1 collaboration

Karthikeyan Murugesan 1 collaboration

Tuong-Vi Nguyen 1 collaboration

Tarek Sahmoud 1 collaboration

Michael J Wick 1 collaboration

Xun Zhang 1 collaboration

Frédéric H Vaillancourt 1 collaboration

Yubao Wang 1 collaboration

Caroline F Ribeiro 1 collaboration

Cherubin Manokaran 1 collaboration

Hyeyoun Chang 1 collaboration

Thanh Von 1 collaboration

Silvia Rodrigues 1 collaboration

Onur Cizmecioglu 1 collaboration

Shidong Jia 1 collaboration

Zhigang Wang 1 collaboration

Fabienne Schmit 1 collaboration

Lan Jiang 1 collaboration

Raymond Pagliarini 1 collaboration

Yi Yang 1 collaboration

Isha Sethi 1 collaboration

Sabina Signoretti 1 collaboration

Guo-Cheng Yuan 1 collaboration

Massimo Loda 1 collaboration

Jean J Zhao 1 collaboration

Thomas M Roberts 1 collaboration

Mackenzie J Parker 1 collaboration

Hyelee Lee 1 collaboration

Sunil Hwang 1 collaboration

Kylie Belanger 1 collaboration

Sofia Woo de Mare 1 collaboration

Richard Surgenor 1 collaboration

Lu Yan 1 collaboration

Shravan Morla 1 collaboration

Peng Hsiao 1 collaboration

Paul Dransfield 1 collaboration

Nathalie Rioux 1 collaboration

Sherri Smith 1 collaboration

Raghav Yelamanchi 1 collaboration

Nikhil Gupta 1 collaboration

C K Durga 1 collaboration

Manit Korpal 1 collaboration

Craig Karr 1 collaboration

Jennifer Tsai 1 collaboration

Ardian S Wibowo 1 collaboration

Alexey A Dementiev 1 collaboration

Joyce Yang 1 collaboration

Jason Lowe 1 collaboration

Lorna Mitchell 1 collaboration

Sabine Ruppel 1 collaboration

Krzysztof Pastuszak 1 collaboration

Michał Sieczczyński 1 collaboration

Marta Dzięgielewska 1 collaboration

Rafał Wolniak 1 collaboration

Agata Drewnowska 1 collaboration

Marcel Korpal 1 collaboration

Laura Zembrzuska 1 collaboration

Anna Supernat 1 collaboration

Anna J Żaczek 1 collaboration