Ana Maria Cuervo

Affiliations

Departments of Medicine and of Developmental and Molecular Biology and Institute for Aging Studies, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Publications (23)

A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy.

Science translational medicine

Avec: Israel Hernandez , Gabriel Luna , Jennifer N Rauch , Surya A Reis , Michel Giroux , Celeste M Karch , Daniel Boctor , Youssef E Sibih , Nadia J Storm , Antonio Diaz , Susmita Kaushik , Cezary Zekanowski , Alexander A Kang , Cassidy R Hinman , Vesna Cerovac , Elmer Guzman , Honjun Zhou , Stephen J Haggarty , Alison M Goate , Steven K Fisher , Ana M Cuervo , Kenneth S Kosik

The negative effect of lipid challenge on autophagy inhibits T cell responses.

Autophagy

Avec: Ignacio Guerrero-Ros , Cristina C Clement , Cara A Reynolds , Bindi Patel , Laura Santambrogio , Ana M Cuervo , Fernando Macian

Cav-1 (Caveolin-1) Deficiency Increases Autophagy in the Endothelium and Attenuates Vascular Inflammation and Atherosclerosis.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Xinbo Zhang , Cristina M Ramírez , Binod Aryal , Julio Madrigal-Matute , Xinran Liu , Antonio Diaz , Marta Torrecilla-Parra , Yajaira Suárez , Ana M Cuervo , William C Sessa , Carlos Fernández-Hernando

PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression.

Cancer cell

Avec: Yotaro Kudo , Masayuki Sugimoto , Esperanza Arias , Hiroaki Kasashima , Thekla Cordes , Juan F Linares , Angeles Duran , Yuki Nakanishi , Naoko Nakanishi , Antoine L'Hermitte , Alex Campos , Nadia Senni , Tarmo Rooslid , Lewis R Roberts , Ana Maria Cuervo , Christian M Metallo , Michael Karin , Maria T Diaz-Meco , Jorge Moscat

HIV Nef and Antiretroviral Therapy Have an Inhibitory Effect on Autophagy in Human Astrocytes that May Contribute to HIV-Associated Neurocognitive Disorders.

Cells

Avec: Laura Cheney , Hillary Guzik , Frank P Macaluso , Fernando Macian , Ana Maria Cuervo , Joan W Berman

Investigating the utility of traditional and genomic multi-locus datasets to resolve relationships in Lipaugus and Tijuca (Cotingidae).

Molecular phylogenetics and evolution

Avec: Amie E Settlecowski , Andrés M Cuervo , José G Tello , Michael G Harvey , Robb T Brumfield , Elizabeth P Derryberry

PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis.

Molecular cell

Avec: Juan F Linares , Xiao Zhang , Anxo Martinez-Ordoñez , Angeles Duran , Hiroto Kinoshita , Hiroaki Kasashima , Naoko Nakanishi , Yuki Nakanishi , Ryan Carelli , Luca Cappelli , Esperanza Arias , Masakazu Yashiro , Masaichi Ohira , Sanjay Patel , Giorgio Inghirami , Massimo Loda , Ana Maria Cuervo , Maria T Diaz-Meco , Jorge Moscat

Chaperone-mediated autophagy sustains haematopoietic stem-cell function.

Nature

Avec: Shuxian Dong , Qian Wang , Yun-Ruei Kao , Antonio Diaz , Inmaculada Tasset , Susmita Kaushik , Victor Thiruthuvanathan , Aliona Zintiridou , Edward Nieves , Monika Dzieciatkowska , Julie A Reisz , Evripidis Gavathiotis , Angelo D'Alessandro , Britta Will , Ana Maria Cuervo

Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.

Science advances

Avec: Sheng-Han Kuo , Inmaculada Tasset , Melody M Cheng , Antonio Diaz , Ming-Kai Pan , Ori J Lieberman , Samantha J Hutten , Roy N Alcalay , Sangjun Kim , Pilar Ximénez-Embún , Li Fan , Donghoon Kim , Han Seok Ko , Talene Yacoubian , Ellen Kanter , Ling Liu , Guomei Tang , Javier Muñoz , Sergio Pablo Sardi , Aiqun Li , Li Gan , Ana Maria Cuervo , David Sulzer

Circadian remodeling of the proteome by chaperone-mediated autophagy.

Autophagy

Avec: Susmita Kaushik , Yves R Juste , Ana Maria Cuervo

Autophagy gene expression in skeletal muscle of older individuals is associated with physical performance, muscle volume and mitochondrial function in the study of muscle, mobility and aging (SOMMA).

Aging cell

Avec: Paul M Coen , Zhiguang Huo , Gregory J Tranah , Haley N Barnes , Xiping Zhang , Christopher A Wolff , Kevin Wu , Peggy M Cawthon , Russell T Hepple , Frederico G S Toledo , Daniel S Evans , Olaya Santiago-Fernández , Ana Maria Cuervo , Stephen B Kritchevsky , Anne B Newman , Steven R Cummings , Karyn A Esser

Reduced endosomal microautophagy activity in aging associates with enhanced exocyst-mediated protein secretion.

Aging cell

Avec: Gregory J Krause , Antonio Diaz , Maryam Jafari , Rabia R Khawaja , Esperanza Agullo-Pascual , Olaya Santiago-Fernández , Alicia L Richards , Kuei-Ho Chen , Phillip Dmitriev , Yan Sun , Stephanie K See , Kotb Abdelmohsen , Krystyna Mazan-Mamczarz , Nevan J Krogan , Myriam Gorospe , Danielle L Swaney , Simone Sidoli , Jose Javier Bravo-Cordero , Martin Kampmann , Ana Maria Cuervo

Restoration of LAMP2A expression in old mice leads to changes in the T cell compartment that support improved immune function.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Cara A Reynolds , Sandra Pelka , Floralba Gjergjova , Inmaculada Tasset , Rabia R Khawaja , Kristen Lindenau , Gregory J Krause , Evripidis Gavathiotis , Ana Maria Cuervo , Fernando Macian

Earth history and the passerine superradiation.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Carl H Oliveros , Daniel J Field , Daniel T Ksepka , F Keith Barker , Alexandre Aleixo , Michael J Andersen , Per Alström , Brett W Benz , Edward L Braun , Michael J Braun , Gustavo A Bravo , Robb T Brumfield , R Terry Chesser , Santiago Claramunt , Joel Cracraft , Andrés M Cuervo , Elizabeth P Derryberry , Travis C Glenn , Michael G Harvey , Peter A Hosner , Leo Joseph , Rebecca T Kimball , Andrew L Mack , Colin M Miskelly , A Townsend Peterson , Mark B Robbins , Frederick H Sheldon , Luís Fábio Silveira , Brian Tilston Smith , Noor D White , Robert G Moyle , Brant C Faircloth

Analysis of Chaperone-Mediated Autophagy.

Methods in molecular biology (Clifton, N.J.)

Avec: Y R Juste , A M Cuervo

Autophagy in major human diseases.

The EMBO journal

Avec: Daniel J Klionsky , Giulia Petroni , Ravi K Amaravadi , Eric H Baehrecke , Andrea Ballabio , Patricia Boya , José Manuel Bravo-San Pedro , Ken Cadwell , Francesco Cecconi , Augustine M K Choi , Mary E Choi , Charleen T Chu , Patrice Codogno , Maria Isabel Colombo , Ana Maria Cuervo , Vojo Deretic , Ivan Dikic , Zvulun Elazar , Eeva-Liisa Eskelinen , Gian Maria Fimia , David A Gewirtz , Douglas R Green , Malene Hansen , Marja Jäättelä , Terje Johansen , Gábor Juhász , Vassiliki Karantza , Claudine Kraft , Guido Kroemer , Nicholas T Ktistakis , Sharad Kumar , Carlos Lopez-Otin , Kay F Macleod , Frank Madeo , Jennifer Martinez , Alicia Meléndez , Noboru Mizushima , Christian Münz , Josef M Penninger , Rushika M Perera , Mauro Piacentini , Fulvio Reggiori , David C Rubinsztein , Kevin M Ryan , Junichi Sadoshima , Laura Santambrogio , Luca Scorrano , Hans-Uwe Simon , Anna Katharina Simon , Anne Simonsen , Alexandra Stolz , Nektarios Tavernarakis , Sharon A Tooze , Tamotsu Yoshimori , Junying Yuan , Zhenyu Yue , Qing Zhong , Lorenzo Galluzzi , Federico Pietrocola

Reciprocal regulation of chaperone-mediated autophagy and the circadian clock.

Nature cell biology

Avec: Yves R Juste , Susmita Kaushik , Mathieu Bourdenx , Ranee Aflakpui , Sanmay Bandyopadhyay , Fernando Garcia , Antonio Diaz , Kristen Lindenau , Vincent Tu , Gregory J Krause , Maryam Jafari , Rajat Singh , Javier Muñoz , Fernando Macian , Ana Maria Cuervo

Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia.

Acta neuropathologica

Avec: Ethan G Geier , Mathieu Bourdenx , Nadia J Storm , J Nicholas Cochran , Daniel W Sirkis , Ji-Hye Hwang , Luke W Bonham , Eliana Marisa Ramos , Antonio Diaz , Victoria Van Berlo , Deepika Dokuru , Alissa L Nana , Anna Karydas , Maureen E Balestra , Yadong Huang , Silvia P Russo , Salvatore Spina , Lea T Grinberg , William W Seeley , Richard M Myers , Bruce L Miller , Giovanni Coppola , Suzee E Lee , Ana Maria Cuervo , Jennifer S Yokoyama

TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy.

Science advances

Avec: Carolina Alquezar , Kathleen M Schoch , Ethan G Geier , Eliana Marisa Ramos , Aurora Scrivo , Kathy H Li , Andrea R Argouarch , Elisabeth E Mlynarski , Beth Dombroski , Michael DeTure , Dennis W Dickson , Jennifer S Yokoyama , Ana M Cuervo , Alma L Burlingame , Gerard D Schellenberg , Timothy M Miller , Bruce L Miller , Aimee W Kao

In Vivo Remodeling of Altered Autophagy-Lysosomal Pathway by a Phosphopeptide in Lupus.

Cells

Avec: Fengjuan Wang , Inmaculada Tasset , Ana Maria Cuervo , Sylviane Muller

Correction: Proteome-wide analysis of chaperone-mediated autophagy targeting motifs.

PLoS biology

Avec: Philipp Kirchner , Mathieu Bourdenx , Julio Madrigal-Matute , Simoni Tiano , Antonio Diaz , Boris A Bartholdy , Britta Will , Ana Maria Cuervo

Autophagy and the hallmarks of aging.

Ageing research reviews

Avec: Susmita Kaushik , Inmaculada Tasset , Esperanza Arias , Olatz Pampliega , Esther Wong , Marta Martinez-Vicente , Ana Maria Cuervo

Autophagy gene expression in skeletal muscle of older individuals is associated with physical performance, muscle volume and mitochondrial function in the Study of Muscle, Mobility and Aging (SOMMA).

medRxiv : the preprint server for health sciences

Avec: Paul M Coen , Zhiguang Huo , Gregory J Tranah , Haley N Barnes , Peggy M Cawthon , Russell T Hepple , Frederico G S Toledo , Daniel S Evans , Olaya Santiago Fernández , Ana Maria Cuervo , Steven B Kritchevsky , Anne B Newman , Steven R Cummings , Karyn A Esser

Réseau de co-auteurs

Antonio Diaz 8 collaborations

Susmita Kaushik 5 collaborations

Inmaculada Tasset 5 collaborations

Ana M Cuervo 4 collaborations

Fernando Macian 4 collaborations

Esperanza Arias 3 collaborations

Gregory J Krause 3 collaborations

Mathieu Bourdenx 3 collaborations

Nadia J Storm 2 collaborations

Cara A Reynolds 2 collaborations

Laura Santambrogio 2 collaborations

Julio Madrigal-Matute 2 collaborations

Hiroaki Kasashima 2 collaborations

Juan F Linares 2 collaborations

Angeles Duran 2 collaborations

Yuki Nakanishi 2 collaborations

Naoko Nakanishi 2 collaborations

Maria T Diaz-Meco 2 collaborations

Jorge Moscat 2 collaborations

Andrés M Cuervo 2 collaborations

Michael G Harvey 2 collaborations

Robb T Brumfield 2 collaborations

Elizabeth P Derryberry 2 collaborations

Evripidis Gavathiotis 2 collaborations

Britta Will 2 collaborations

Javier Muñoz 2 collaborations

Yves R Juste 2 collaborations

Paul M Coen 2 collaborations

Zhiguang Huo 2 collaborations

Gregory J Tranah 2 collaborations

Haley N Barnes 2 collaborations

Peggy M Cawthon 2 collaborations

Russell T Hepple 2 collaborations

Frederico G S Toledo 2 collaborations

Daniel S Evans 2 collaborations

Olaya Santiago-Fernández 2 collaborations

Anne B Newman 2 collaborations

Steven R Cummings 2 collaborations

Karyn A Esser 2 collaborations

Maryam Jafari 2 collaborations

Rabia R Khawaja 2 collaborations

Kristen Lindenau 2 collaborations

Ethan G Geier 2 collaborations

Eliana Marisa Ramos 2 collaborations

Bruce L Miller 2 collaborations

Jennifer S Yokoyama 2 collaborations

Israel Hernandez 1 collaboration

Gabriel Luna 1 collaboration

Jennifer N Rauch 1 collaboration

Surya A Reis 1 collaboration

Michel Giroux 1 collaboration

Celeste M Karch 1 collaboration

Daniel Boctor 1 collaboration

Youssef E Sibih 1 collaboration

Cezary Zekanowski 1 collaboration

Alexander A Kang 1 collaboration

Cassidy R Hinman 1 collaboration

Vesna Cerovac 1 collaboration

Elmer Guzman 1 collaboration

Honjun Zhou 1 collaboration

Stephen J Haggarty 1 collaboration

Alison M Goate 1 collaboration

Steven K Fisher 1 collaboration

Kenneth S Kosik 1 collaboration

Ignacio Guerrero-Ros 1 collaboration

Cristina C Clement 1 collaboration

Bindi Patel 1 collaboration

Xinbo Zhang 1 collaboration

Cristina M Ramírez 1 collaboration

Binod Aryal 1 collaboration

Xinran Liu 1 collaboration

Marta Torrecilla-Parra 1 collaboration

Yajaira Suárez 1 collaboration

William C Sessa 1 collaboration

Carlos Fernández-Hernando 1 collaboration

Yotaro Kudo 1 collaboration

Masayuki Sugimoto 1 collaboration

Thekla Cordes 1 collaboration

Antoine L'Hermitte 1 collaboration

Alex Campos 1 collaboration

Nadia Senni 1 collaboration

Tarmo Rooslid 1 collaboration

Lewis R Roberts 1 collaboration

Christian M Metallo 1 collaboration

Michael Karin 1 collaboration

Laura Cheney 1 collaboration

Hillary Guzik 1 collaboration

Frank P Macaluso 1 collaboration

Joan W Berman 1 collaboration

Amie E Settlecowski 1 collaboration

José G Tello 1 collaboration

Xiao Zhang 1 collaboration

Anxo Martinez-Ordoñez 1 collaboration

Hiroto Kinoshita 1 collaboration

Ryan Carelli 1 collaboration

Luca Cappelli 1 collaboration

Masakazu Yashiro 1 collaboration

Masaichi Ohira 1 collaboration

Sanjay Patel 1 collaboration

Giorgio Inghirami 1 collaboration

Massimo Loda 1 collaboration

Shuxian Dong 1 collaboration

Qian Wang 1 collaboration

Yun-Ruei Kao 1 collaboration

Victor Thiruthuvanathan 1 collaboration

Aliona Zintiridou 1 collaboration

Edward Nieves 1 collaboration

Monika Dzieciatkowska 1 collaboration

Julie A Reisz 1 collaboration

Angelo D'Alessandro 1 collaboration

Sheng-Han Kuo 1 collaboration

Melody M Cheng 1 collaboration

Ming-Kai Pan 1 collaboration

Ori J Lieberman 1 collaboration

Samantha J Hutten 1 collaboration

Roy N Alcalay 1 collaboration

Sangjun Kim 1 collaboration

Pilar Ximénez-Embún 1 collaboration

Li Fan 1 collaboration

Donghoon Kim 1 collaboration

Han Seok Ko 1 collaboration

Talene Yacoubian 1 collaboration

Ellen Kanter 1 collaboration

Ling Liu 1 collaboration

Guomei Tang 1 collaboration

Sergio Pablo Sardi 1 collaboration

Aiqun Li 1 collaboration

Li Gan 1 collaboration

David Sulzer 1 collaboration

Xiping Zhang 1 collaboration

Christopher A Wolff 1 collaboration

Kevin Wu 1 collaboration

Stephen B Kritchevsky 1 collaboration

Esperanza Agullo-Pascual 1 collaboration

Alicia L Richards 1 collaboration

Kuei-Ho Chen 1 collaboration

Phillip Dmitriev 1 collaboration

Yan Sun 1 collaboration

Stephanie K See 1 collaboration

Kotb Abdelmohsen 1 collaboration

Krystyna Mazan-Mamczarz 1 collaboration

Nevan J Krogan 1 collaboration

Myriam Gorospe 1 collaboration

Danielle L Swaney 1 collaboration

Simone Sidoli 1 collaboration

Jose Javier Bravo-Cordero 1 collaboration

Martin Kampmann 1 collaboration

Sandra Pelka 1 collaboration

Floralba Gjergjova 1 collaboration

Carl H Oliveros 1 collaboration

Daniel J Field 1 collaboration

Daniel T Ksepka 1 collaboration

F Keith Barker 1 collaboration

Alexandre Aleixo 1 collaboration

Michael J Andersen 1 collaboration

Per Alström 1 collaboration

Brett W Benz 1 collaboration

Edward L Braun 1 collaboration

Michael J Braun 1 collaboration

Gustavo A Bravo 1 collaboration

R Terry Chesser 1 collaboration

Santiago Claramunt 1 collaboration

Joel Cracraft 1 collaboration

Travis C Glenn 1 collaboration

Peter A Hosner 1 collaboration

Leo Joseph 1 collaboration

Rebecca T Kimball 1 collaboration

Andrew L Mack 1 collaboration

Colin M Miskelly 1 collaboration

A Townsend Peterson 1 collaboration

Mark B Robbins 1 collaboration

Frederick H Sheldon 1 collaboration

Luís Fábio Silveira 1 collaboration

Brian Tilston Smith 1 collaboration

Noor D White 1 collaboration

Robert G Moyle 1 collaboration

Brant C Faircloth 1 collaboration

Y R Juste 1 collaboration

A M Cuervo 1 collaboration

Daniel J Klionsky 1 collaboration

Giulia Petroni 1 collaboration

Ravi K Amaravadi 1 collaboration

Eric H Baehrecke 1 collaboration

Andrea Ballabio 1 collaboration

Patricia Boya 1 collaboration

José Manuel Bravo-San Pedro 1 collaboration

Ken Cadwell 1 collaboration

Francesco Cecconi 1 collaboration

Augustine M K Choi 1 collaboration

Mary E Choi 1 collaboration

Charleen T Chu 1 collaboration

Patrice Codogno 1 collaboration

Maria Isabel Colombo 1 collaboration

Vojo Deretic 1 collaboration

Ivan Dikic 1 collaboration

Zvulun Elazar 1 collaboration

Eeva-Liisa Eskelinen 1 collaboration

Gian Maria Fimia 1 collaboration

David A Gewirtz 1 collaboration

Douglas R Green 1 collaboration

Malene Hansen 1 collaboration

Marja Jäättelä 1 collaboration

Terje Johansen 1 collaboration

Gábor Juhász 1 collaboration

Vassiliki Karantza 1 collaboration

Claudine Kraft 1 collaboration

Guido Kroemer 1 collaboration

Nicholas T Ktistakis 1 collaboration

Sharad Kumar 1 collaboration

Carlos Lopez-Otin 1 collaboration

Kay F Macleod 1 collaboration

Frank Madeo 1 collaboration

Jennifer Martinez 1 collaboration

Alicia Meléndez 1 collaboration

Noboru Mizushima 1 collaboration

Christian Münz 1 collaboration

Josef M Penninger 1 collaboration

Rushika M Perera 1 collaboration

Mauro Piacentini 1 collaboration

Fulvio Reggiori 1 collaboration

David C Rubinsztein 1 collaboration

Kevin M Ryan 1 collaboration

Junichi Sadoshima 1 collaboration

Luca Scorrano 1 collaboration

Hans-Uwe Simon 1 collaboration

Anna Katharina Simon 1 collaboration

Anne Simonsen 1 collaboration

Alexandra Stolz 1 collaboration

Nektarios Tavernarakis 1 collaboration

Sharon A Tooze 1 collaboration

Tamotsu Yoshimori 1 collaboration

Junying Yuan 1 collaboration

Zhenyu Yue 1 collaboration

Qing Zhong 1 collaboration

Lorenzo Galluzzi 1 collaboration

Federico Pietrocola 1 collaboration

Ranee Aflakpui 1 collaboration

Sanmay Bandyopadhyay 1 collaboration

Fernando Garcia 1 collaboration

Vincent Tu 1 collaboration

Rajat Singh 1 collaboration

J Nicholas Cochran 1 collaboration

Daniel W Sirkis 1 collaboration

Ji-Hye Hwang 1 collaboration

Luke W Bonham 1 collaboration

Victoria Van Berlo 1 collaboration

Deepika Dokuru 1 collaboration

Alissa L Nana 1 collaboration

Anna Karydas 1 collaboration

Maureen E Balestra 1 collaboration

Yadong Huang 1 collaboration

Silvia P Russo 1 collaboration

Salvatore Spina 1 collaboration

Lea T Grinberg 1 collaboration

William W Seeley 1 collaboration

Richard M Myers 1 collaboration

Giovanni Coppola 1 collaboration

Suzee E Lee 1 collaboration

Carolina Alquezar 1 collaboration

Kathleen M Schoch 1 collaboration

Aurora Scrivo 1 collaboration

Kathy H Li 1 collaboration

Andrea R Argouarch 1 collaboration

Elisabeth E Mlynarski 1 collaboration

Beth Dombroski 1 collaboration

Michael DeTure 1 collaboration

Dennis W Dickson 1 collaboration

Alma L Burlingame 1 collaboration

Gerard D Schellenberg 1 collaboration

Timothy M Miller 1 collaboration

Aimee W Kao 1 collaboration

Fengjuan Wang 1 collaboration

Sylviane Muller 1 collaboration

Philipp Kirchner 1 collaboration

Simoni Tiano 1 collaboration

Boris A Bartholdy 1 collaboration

Olatz Pampliega 1 collaboration

Esther Wong 1 collaboration

Marta Martinez-Vicente 1 collaboration

Olaya Santiago Fernández 1 collaboration

Steven B Kritchevsky 1 collaboration