Roderick T Bronson

Affiliations

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, United States of America.

Publications (18)

BRAF V600E and Pten deletion in mice produces a histiocytic disorder with features of Langerhans cell histiocytosis.

PloS one

Avec: David S Nelson , Ryan L Marano , Yechaan Joo , Sara Y Tian , Bhumi Patel , Daniel H Kaplan , Mark J Shlomchik , Kristen Stevenson , Roderick T Bronson , Barrett J Rollins

CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Sheng Rong Ng , William M Rideout , Elliot H Akama-Garren , Arjun Bhutkar , Kim L Mercer , Jason M Schenkel , Roderick T Bronson , Tyler Jacks

Targeting the cyclin-dependent kinase 5 in metastatic melanoma.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Samanta Sharma , Tian Zhang , Wojciech Michowski , Vito W Rebecca , Min Xiao , Roberta Ferretti , Jan M Suski , Roderick T Bronson , Joao A Paulo , Dennie Frederick , Anne Fassl , Genevieve M Boland , Yan Geng , Jacqueline A Lees , Rene H Medema , Meenhard Herlyn , Steven P Gygi , Piotr Sicinski

Navitoclax enhances the effectiveness of EGFR-targeted antibody-drug conjugates in PDX models of EGFR-expressing triple-negative breast cancer.

Breast cancer research : BCR

Avec: Jason J Zoeller , Aleksandr Vagodny , Veerle W Daniels , Krishan Taneja , Benjamin Y Tan , Yoko S DeRose , Maihi Fujita , Alana L Welm , Anthony Letai , Joel D Leverson , Vincent Blot , Roderick T Bronson , Deborah A Dillon , Joan S Brugge

Transient commensal clonal interactions can drive tumor metastasis.

Nature communications

Avec: Suha Naffar-Abu Amara , Hendrik J Kuiken , Laura M Selfors , Timothy Butler , Marco L Leung , Cheuk T Leung , Elaine P Kuhn , Teodora Kolarova , Carina Hage , Kripa Ganesh , Richard Panayiotou , Rosemary Foster , Bo R Rueda , Athena Aktipis , Paul Spellman , Tan A Ince , Joanne Xiu , Matthew Oberley , Zoran Gatalica , Nicholas Navin , Gordon B Mills , Rodrick T Bronson , Joan S Brugge

Development of a MEK inhibitor, NFX-179, as a chemoprevention agent for squamous cell carcinoma.

Science translational medicine

Avec: Kavita Y Sarin , John Kincaid , Brittney Sell , Jahanbanoo Shahryari , Matthew A J Duncton , Elaine Morefield , Wenchao Sun , Karol Prieto , Omar Chavez-Chiang , Carlos de Moran Segura , Jonathan Nguyen , Roderick T Bronson , Scott R Plotkin , Gerd G Kochendoerfer , Peter Fenn , Michael A Wootton , Christopher Powala , Mark P de Souza , Kenneth Y Tsai

Targeted inhibition of Wnt signaling with a Clostridioides difficile toxin B fragment suppresses breast cancer tumor growth.

PLoS biology

Avec: Aina He , Songhai Tian , Oded Kopper , Daniel J Horan , Peng Chen , Roderick T Bronson , Ren Sheng , Hao Wu , Lufei Sui , Kun Zhou , Liang Tao , Quan Wu , Yujing Huang , Zan Shen , Sen Han , Xueqing Chen , Hong Chen , Xi He , Alexander G Robling , Rongsheng Jin , Hans Clevers , Dongxi Xiang , Zhe Li , Min Dong

Adhesive anti-fibrotic interfaces on diverse organs.

Nature

Avec: Jingjing Wu , Jue Deng , Georgios Theocharidis , Tiffany L Sarrafian , Leigh G Griffiths , Roderick T Bronson , Aristidis Veves , Jianzhu Chen , Hyunwoo Yuk , Xuanhe Zhao

MAX inactivation deregulates the MYC network and induces neuroendocrine neoplasia in multiple tissues.

bioRxiv : the preprint server for biology

Avec: Brian Freie , Ali H Ibrahim , Patrick A Carroll , Roderick T Bronson , Arnaud Augert , David MacPherson , Robert N Eisenman

Long-Term Therapeutic Efficacy of Intravenous AAV-Mediated Hamartin Replacement in Mouse Model of Tuberous Sclerosis Type 1.

Molecular therapy. Methods & clinical development

Avec: Shilpa Prabhakar , Pike See Cheah , Xuan Zhang , Max Zinter , Maria Gianatasio , Eloise Hudry , Roderick T Bronson , David J Kwiatkowski , Anat Stemmer-Rachamimov , Casey A Maguire , Miguel Sena-Esteves , Bakhos A Tannous , Xandra O Breakefield

The crucial role of DNA-dependent protein kinase and myelin transcription factor 1-like protein in the miR-141 tumor suppressor network.

Cell cycle (Georgetown, Tex.)

Avec: Bo Wang , Dongping Li , Youli Yao , Mieke Heyns , Anna Kovalchuk , Yaroslav Ilnytskyy , Rocio Rodriguez-Juarez , Roderick T Bronson , Gerlinde A S Metz , Olga Kovalchuk , Igor Kovalchuk

Intergenerational epigenetic inheritance of cancer susceptibility in mammals.

eLife

Avec: Bluma J Lesch , Zuzana Tothova , Elizabeth A Morgan , Zhicong Liao , Roderick T Bronson , Benjamin L Ebert , David C Page

A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells.

Nature communications

Avec: Rupesh S Patel , Rodrigo Romero , Emma V Watson , Anthony C Liang , Megan Burger , Peter M K Westcott , Kim L Mercer , Roderick T Bronson , Eric C Wooten , Arjun Bhutkar , Tyler Jacks , Stephen J Elledge

Oncogenic Events Dictate the Types and Locations of Gynecological Malignancies Originating from

Cancers

Avec: Eun-Sil Park , Dongxi Xiang , Ying Xie , Roderick T Bronson , Zhe Li

Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer.

Cancer research

Avec: Deli Hong , Erik H Knelson , Yixiang Li , Yavuz T Durmaz , Wenhua Gao , Emily Walton , Amir Vajdi , Tran Thai , Maura Sticco-Ivins , Amin H Sabet , Kristen L Jones , Anna C Schinzel , Rod T Bronson , Quang-De Nguyen , Michael Y Tolstorukov , Marina Vivero , Sabina Signoretti , David A Barbie , Matthew G Oser

Systemic and skin-limited delayed-type drug hypersensitivity reactions associate with distinct resident and recruited T cell subsets.

The Journal of clinical investigation

Avec: Pranali N Shah , George A Romar , Artür Manukyan , Wei-Che Ko , Pei-Chen Hsieh , Gustavo A Velasquez , Elisa M Schunkert , Xiaopeng Fu , Indira Guleria , Roderick T Bronson , Kevin Wei , Abigail H Waldman , Frank R Vleugels , Marilyn G Liang , Anita Giobbie-Hurder , Arash Mostaghimi , Birgitta Ar Schmidt , Victor Barrera , Ruth K Foreman , Manuel Garber , Sherrie J Divito

Fitm2 is required for ER homeostasis and normal function of murine liver.

The Journal of biological chemistry

Avec: Laura M Bond , Ayon Ibrahim , Zon W Lai , Rosemary L Walzem , Roderick T Bronson , Olga R Ilkayeva , Tobias C Walther , Robert V Farese

KDM6A epigenetically regulates subtype plasticity in small cell lung cancer.

Nature cell biology

Avec: Leslie Duplaquet , Yixiang Li , Matthew A Booker , Yingtian Xie , Sarah Naomi Olsen , Radhika A Patel , Deli Hong , Charlie Hatton , Thomas Denize , Emily Walton , Yasmin N Laimon , Rong Li , Yijia Jiang , Roderick T Bronson , Jackson Southard , Shuqiang Li , Sabina Signoretti , Xintao Qiu , Paloma Cejas , Scott A Armstrong , Henry W Long , Michael Y Tolstorukov , Michael C Haffner , Matthew G Oser

Réseau de co-auteurs

Arjun Bhutkar 2 collaborations

Kim L Mercer 2 collaborations

Tyler Jacks 2 collaborations

Joan S Brugge 2 collaborations

Dongxi Xiang 2 collaborations

Zhe Li 2 collaborations

Deli Hong 2 collaborations

Yixiang Li 2 collaborations

Emily Walton 2 collaborations

Michael Y Tolstorukov 2 collaborations

Sabina Signoretti 2 collaborations

Matthew G Oser 2 collaborations

David S Nelson 1 collaboration

Ryan L Marano 1 collaboration

Yechaan Joo 1 collaboration

Sara Y Tian 1 collaboration

Bhumi Patel 1 collaboration

Daniel H Kaplan 1 collaboration

Mark J Shlomchik 1 collaboration

Kristen Stevenson 1 collaboration

Barrett J Rollins 1 collaboration

Sheng Rong Ng 1 collaboration

William M Rideout 1 collaboration

Elliot H Akama-Garren 1 collaboration

Jason M Schenkel 1 collaboration

Samanta Sharma 1 collaboration

Tian Zhang 1 collaboration

Wojciech Michowski 1 collaboration

Vito W Rebecca 1 collaboration

Min Xiao 1 collaboration

Roberta Ferretti 1 collaboration

Jan M Suski 1 collaboration

Joao A Paulo 1 collaboration

Dennie Frederick 1 collaboration

Anne Fassl 1 collaboration

Genevieve M Boland 1 collaboration

Yan Geng 1 collaboration

Jacqueline A Lees 1 collaboration

Rene H Medema 1 collaboration

Meenhard Herlyn 1 collaboration

Steven P Gygi 1 collaboration

Piotr Sicinski 1 collaboration

Jason J Zoeller 1 collaboration

Aleksandr Vagodny 1 collaboration

Veerle W Daniels 1 collaboration

Krishan Taneja 1 collaboration

Benjamin Y Tan 1 collaboration

Yoko S DeRose 1 collaboration

Maihi Fujita 1 collaboration

Alana L Welm 1 collaboration

Anthony Letai 1 collaboration

Joel D Leverson 1 collaboration

Vincent Blot 1 collaboration

Deborah A Dillon 1 collaboration

Suha Naffar-Abu Amara 1 collaboration

Hendrik J Kuiken 1 collaboration

Laura M Selfors 1 collaboration

Timothy Butler 1 collaboration

Marco L Leung 1 collaboration

Cheuk T Leung 1 collaboration

Elaine P Kuhn 1 collaboration

Teodora Kolarova 1 collaboration

Carina Hage 1 collaboration

Kripa Ganesh 1 collaboration

Richard Panayiotou 1 collaboration

Rosemary Foster 1 collaboration

Bo R Rueda 1 collaboration

Athena Aktipis 1 collaboration

Paul Spellman 1 collaboration

Tan A Ince 1 collaboration

Joanne Xiu 1 collaboration

Matthew Oberley 1 collaboration

Zoran Gatalica 1 collaboration

Nicholas Navin 1 collaboration

Gordon B Mills 1 collaboration

Rodrick T Bronson 1 collaboration

Kavita Y Sarin 1 collaboration

John Kincaid 1 collaboration

Brittney Sell 1 collaboration

Jahanbanoo Shahryari 1 collaboration

Matthew A J Duncton 1 collaboration

Elaine Morefield 1 collaboration

Wenchao Sun 1 collaboration

Karol Prieto 1 collaboration

Omar Chavez-Chiang 1 collaboration

Carlos de Moran Segura 1 collaboration

Jonathan Nguyen 1 collaboration

Scott R Plotkin 1 collaboration

Gerd G Kochendoerfer 1 collaboration

Peter Fenn 1 collaboration

Michael A Wootton 1 collaboration

Christopher Powala 1 collaboration

Mark P de Souza 1 collaboration

Kenneth Y Tsai 1 collaboration

Aina He 1 collaboration

Songhai Tian 1 collaboration

Oded Kopper 1 collaboration

Daniel J Horan 1 collaboration

Peng Chen 1 collaboration

Ren Sheng 1 collaboration

Hao Wu 1 collaboration

Lufei Sui 1 collaboration

Kun Zhou 1 collaboration

Liang Tao 1 collaboration

Quan Wu 1 collaboration

Yujing Huang 1 collaboration

Zan Shen 1 collaboration

Sen Han 1 collaboration

Xueqing Chen 1 collaboration

Hong Chen 1 collaboration

Xi He 1 collaboration

Alexander G Robling 1 collaboration

Rongsheng Jin 1 collaboration

Hans Clevers 1 collaboration

Min Dong 1 collaboration

Jingjing Wu 1 collaboration

Jue Deng 1 collaboration

Georgios Theocharidis 1 collaboration

Tiffany L Sarrafian 1 collaboration

Leigh G Griffiths 1 collaboration

Aristidis Veves 1 collaboration

Jianzhu Chen 1 collaboration

Hyunwoo Yuk 1 collaboration

Xuanhe Zhao 1 collaboration

Brian Freie 1 collaboration

Ali H Ibrahim 1 collaboration

Patrick A Carroll 1 collaboration

Arnaud Augert 1 collaboration

David MacPherson 1 collaboration

Robert N Eisenman 1 collaboration

Shilpa Prabhakar 1 collaboration

Pike See Cheah 1 collaboration

Xuan Zhang 1 collaboration

Max Zinter 1 collaboration

Maria Gianatasio 1 collaboration

Eloise Hudry 1 collaboration

David J Kwiatkowski 1 collaboration

Anat Stemmer-Rachamimov 1 collaboration

Casey A Maguire 1 collaboration

Miguel Sena-Esteves 1 collaboration

Bakhos A Tannous 1 collaboration

Xandra O Breakefield 1 collaboration

Bo Wang 1 collaboration

Dongping Li 1 collaboration

Youli Yao 1 collaboration

Mieke Heyns 1 collaboration

Anna Kovalchuk 1 collaboration

Yaroslav Ilnytskyy 1 collaboration

Rocio Rodriguez-Juarez 1 collaboration

Gerlinde A S Metz 1 collaboration

Olga Kovalchuk 1 collaboration

Igor Kovalchuk 1 collaboration

Bluma J Lesch 1 collaboration

Zuzana Tothova 1 collaboration

Elizabeth A Morgan 1 collaboration

Zhicong Liao 1 collaboration

Benjamin L Ebert 1 collaboration

David C Page 1 collaboration

Rupesh S Patel 1 collaboration

Rodrigo Romero 1 collaboration

Emma V Watson 1 collaboration

Anthony C Liang 1 collaboration

Megan Burger 1 collaboration

Peter M K Westcott 1 collaboration

Eric C Wooten 1 collaboration

Stephen J Elledge 1 collaboration

Eun-Sil Park 1 collaboration

Ying Xie 1 collaboration

Erik H Knelson 1 collaboration

Yavuz T Durmaz 1 collaboration

Wenhua Gao 1 collaboration

Amir Vajdi 1 collaboration

Tran Thai 1 collaboration

Maura Sticco-Ivins 1 collaboration

Amin H Sabet 1 collaboration

Kristen L Jones 1 collaboration

Anna C Schinzel 1 collaboration

Rod T Bronson 1 collaboration

Quang-De Nguyen 1 collaboration

Marina Vivero 1 collaboration

David A Barbie 1 collaboration

Pranali N Shah 1 collaboration

George A Romar 1 collaboration

Artür Manukyan 1 collaboration

Wei-Che Ko 1 collaboration

Pei-Chen Hsieh 1 collaboration

Gustavo A Velasquez 1 collaboration

Elisa M Schunkert 1 collaboration

Xiaopeng Fu 1 collaboration

Indira Guleria 1 collaboration

Kevin Wei 1 collaboration

Abigail H Waldman 1 collaboration

Frank R Vleugels 1 collaboration

Marilyn G Liang 1 collaboration

Anita Giobbie-Hurder 1 collaboration

Arash Mostaghimi 1 collaboration

Birgitta Ar Schmidt 1 collaboration

Victor Barrera 1 collaboration

Ruth K Foreman 1 collaboration

Manuel Garber 1 collaboration

Sherrie J Divito 1 collaboration

Laura M Bond 1 collaboration

Ayon Ibrahim 1 collaboration

Zon W Lai 1 collaboration

Rosemary L Walzem 1 collaboration

Olga R Ilkayeva 1 collaboration

Tobias C Walther 1 collaboration

Robert V Farese 1 collaboration

Leslie Duplaquet 1 collaboration

Matthew A Booker 1 collaboration

Yingtian Xie 1 collaboration

Sarah Naomi Olsen 1 collaboration

Radhika A Patel 1 collaboration

Charlie Hatton 1 collaboration

Thomas Denize 1 collaboration

Yasmin N Laimon 1 collaboration

Rong Li 1 collaboration

Yijia Jiang 1 collaboration

Jackson Southard 1 collaboration

Shuqiang Li 1 collaboration

Xintao Qiu 1 collaboration

Paloma Cejas 1 collaboration

Scott A Armstrong 1 collaboration

Henry W Long 1 collaboration

Michael C Haffner 1 collaboration