Alexander G Robling

Affiliations

Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN, USA.
Department of Biomedical Engineering, Indiana University-Purdue University at Indianapolis, Indianapolis, IN, USA.
Indiana Center for Musculoskeletal Health, Indianapolis, IN, USA.
Richard L. Roudebush VA Medical Center, Indianapolis, IN, USA.

Publications (41)

Expression of a Degradation-Resistant β-Catenin Mutant in Osteocytes Protects the Skeleton From Mechanodeprivation-Induced Bone Wasting.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Avec: Whitney A Bullock , April M Hoggatt , Daniel J Horan , Karl J Lewis , Hiroki Yokota , Steven Hann , Matthew L Warman , Aimy Sebastian , Gabriela G Loots , Fredrick M Pavalko , Alexander G Robling

Skeletal Functions of Voltage Sensitive Calcium Channels.

Current osteoporosis reports

Avec: Christian S Wright , Alexander G Robling , Mary C Farach-Carson , William R Thompson

Nmp4, a Regulator of Induced Osteoanabolism, Also Influences Insulin Secretion and Sensitivity.

Calcified tissue international

Avec: Joseph Bidwell , Sarah A Tersey , Michele Adaway , Robert N Bone , Amy Creecy , Angela Klunk , Emily G Atkinson , Ronald C Wek , Alexander G Robling , Joseph M Wallace , Carmella Evans-Molina

The Osteocyte: New Insights.

Annual review of physiology

Avec: Alexander G Robling , Lynda F Bonewald

Finite-element analysis of the mouse proximal ulna in response to elbow loading.

Journal of bone and mineral metabolism

Avec: Feifei Jiang , Aydin Jalali , Chie Deguchi , Andy Chen , Shengzhi Liu , Rika Kondo , Kazumasa Minami , Takashi Horiuchi , Bai-Yan Li , Alexander G Robling , Jie Chen , Hiroki Yokota

Combination therapy in the Col1a2

Bone

Avec: Shannon Kaupp , Dan J Horan , Kyung-Eun Lim , Henry A Feldman , Alexander G Robling , Matthew L Warman , Christina M Jacobsen

Loss of

American journal of physiology. Endocrinology and metabolism

Avec: Yu Shao , Emily Wichern , Paul J Childress , Michele Adaway , Jagannath Misra , Angela Klunk , David B Burr , Ronald C Wek , Amber L Mosley , Yunlong Liu , Alexander G Robling , Nickolay Brustovetsky , James Hamilton , Kylie Jacobs , Deepak Vashishth , Keith R Stayrook , Matthew R Allen , Joseph M Wallace , Joseph P Bidwell

Transiently increased serotonin has modest or no effects on bone mass accrual in growing female C57BL6/J or growing male and female Lrp5

Bone

Avec: Caitlin Resendes , Daniel J Horan , Alexander G Robling , Benlian Gao , Ginger L Milne , Matthew L Warman

Sensitive detection of Cre-mediated recombination using droplet digital PCR reveals Tg(BGLAP-Cre) and Tg(DMP1-Cre) are active in multiple non-skeletal tissues.

Bone

Avec: Krishnakali Dasgupta , Samantha Lessard , Steven Hann , Megan E Fowler , Alexander G Robling , Matthew L Warman

Osteocyte RANKL Drives Bone Resorption in Mouse Ligature-Induced Periodontitis.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Avec: Mizuho Kittaka , Tetsuya Yoshimoto , Marcus E Levitan , Rina Urata , Roy B Choi , Yayoi Teno , Yixia Xie , Yukiko Kitase , Matthew Prideaux , Sarah L Dallas , Alexander G Robling , Yasuyoshi Ueki

Single cell cortical bone transcriptomics define novel osteolineage gene sets altered in chronic kidney disease.

Frontiers in endocrinology

Avec: Rafiou Agoro , Intawat Nookaew , Megan L Noonan , Yamil G Marambio , Sheng Liu , Wennan Chang , Hongyu Gao , Lainey M Hibbard , Corinne E Metzger , Daniel Horan , William R Thompson , Xiaoling Xuei , Yunlong Liu , Chi Zhang , Alexander G Robling , Lynda F Bonewald , Jun Wan , Kenneth E White

Perspective: The current state of Cre driver mouse lines in skeletal research: Challenges and opportunities.

Bone

Avec: Connor J Cunningham , Roy B Choi , Whitney A Bullock , Alexander G Robling

Skeletal adaptations in young male mice after 4 weeks aboard the International Space Station.

NPJ microgravity

Avec: Kevin A Maupin , Paul Childress , Alexander Brinker , Faisal Khan , Irushi Abeysekera , Izath Nizeet Aguilar , David J Olivos , Gremah Adam , Michael K Savaglio , Venkateswaran Ganesh , Riley Gorden , Rachel Mannfeld , Elliott Beckner , Daniel J Horan , Alexander G Robling , Nabarun Chakraborty , Aarti Gautam , Rasha Hammamieh , Melissa A Kacena

Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion.

Bone research

Avec: Yao Fan , Aydin Jalali , Andy Chen , Xinyu Zhao , Shengzhi Liu , Meghana Teli , Yunxia Guo , Fangjia Li , Junrui Li , Amanda Siegel , Lianxiang Yang , Jing Liu , Sungsoo Na , Mangilal Agarwal , Alexander G Robling , Harikrishna Nakshatri , Bai-Yan Li , Hiroki Yokota

A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues.

The Journal of biological chemistry

Avec: Austin M Reilly , Shijun Yan , Menghao Huang , Surabhi D Abhyankar , Jason M Conley , Robert N Bone , Natalie D Stull , Daniel J Horan , Hyun C Roh , Alexander G Robling , Aaron C Ericsson , Xiaocheng C Dong , Carmella Evans-Molina , Hongxia Ren

Co-deletion of Lrp5 and Lrp6 in the skeleton severely diminishes bone gain from sclerostin antibody administration.

Bone

Avec: Kyung-Eun Lim , Whitney A Bullock , Daniel J Horan , Bart O Williams , Matthew L Warman , Alexander G Robling

Generation and Characterization of Mouse Models for Skeletal Disease.

Methods in molecular biology (Clifton, N.J.)

Avec: Gabrielle E Foxa , Ye Liu , Lisa M Turner , Alexander G Robling , Tao Yang , Bart O Williams

Notum Deletion From Late-Stage Skeletal Cells Increases Cortical Bone Formation and Potentiates Skeletal Effects of Sclerostin Inhibition.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Avec: Roy B Choi , Whitney A Bullock , April M Hoggatt , Daniel J Horan , Emily Z Pemberton , Jung Min Hong , Xinjun Zhang , Xi He , Alexander G Robling

Sostdc1 Suppression in the Absence of Sclerostin Potentiates Anabolic Action of Cortical Bone in Mice.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Avec: Roy B Choi , April M Hoggatt , Daniel J Horan , Emily Z Rogers , Gabriela G Loots , Alexander G Robling

L-BAIBA Synergizes with Sub-Optimal Mechanical Loading to Promote New Bone Formation.

JBMR plus

Avec: Matt Prideaux , Alberto Smargiassi , Gang Peng , Marco Brotto , Alexander G Robling , Lynda F Bonewald

Targeted inhibition of Wnt signaling with a Clostridioides difficile toxin B fragment suppresses breast cancer tumor growth.

PLoS biology

Avec: Aina He , Songhai Tian , Oded Kopper , Daniel J Horan , Peng Chen , Roderick T Bronson , Ren Sheng , Hao Wu , Lufei Sui , Kun Zhou , Liang Tao , Quan Wu , Yujing Huang , Zan Shen , Sen Han , Xueqing Chen , Hong Chen , Xi He , Alexander G Robling , Rongsheng Jin , Hans Clevers , Dongxi Xiang , Zhe Li , Min Dong

An osteocalcin-deficient mouse strain without endocrine abnormalities.

PLoS genetics

Avec: Cassandra R Diegel , Steven Hann , Ugur M Ayturk , Jennifer C W Hu , Kyung-Eun Lim , Casey J Droscha , Zachary B Madaj , Gabrielle E Foxa , Isaac Izaguirre , Vai Vivarium And Transgenics Core , Noorulain Paracha , Bohdan Pidhaynyy , Terry L Dowd , Alexander G Robling , Matthew L Warman , Bart O Williams

Twist1 Inactivation in Dmp1-Expressing Cells Increases Bone Mass but Does Not Affect the Anabolic Response to Sclerostin Neutralization.

International journal of molecular sciences

Avec: Karl J Lewis , Roy B-J Choi , Emily Z Pemberton , Whitney A Bullock , Anthony B Firulli , Alexander G Robling

Induction of Lrp5 HBM-causing mutations in Cathepsin-K expressing cells alters bone metabolism.

Bone

Avec: Kyung Shin Kang , Jung Min Hong , Daniel J Horan , Kyung-Eun Lim , Whitney A Bullock , Angela Bruzzaniti , Steven Hann , Matthew L Warman , Alexander G Robling

The mTORC2 Component Rictor Is Required for Load-Induced Bone Formation in Late-Stage Skeletal Cells.

JBMR plus

Avec: Karl J Lewis , Xin Yi , Christian S Wright , Emily Z Pemberton , Whitney A Bullock , William R Thompson , Alexander G Robling

Exogenous Oncostatin M induces Cardiac Dysfunction, Musculoskeletal Atrophy, and Fibrosis.

Cytokine

Avec: Daenique H A Jengelley , Meijing Wang , Ashok Narasimhan , Joseph E Rupert , Andrew R Young , Xiaoling Zhong , Daniel J Horan , Alexander G Robling , Leonidas G Koniaris , Teresa A Zimmers

NMP4, an Arbiter of Bone Cell Secretory Capacity and Regulator of Skeletal Response to PTH Therapy.

Calcified tissue international

Avec: Crystal Korff , Emily Atkinson , Michele Adaway , Angela Klunk , Ronald C Wek , Deepak Vashishth , Joseph M Wallace , Emily K Anderson-Baucum , Carmella Evans-Molina , Alexander G Robling , Joseph P Bidwell

Loss of Nmp4 enhances bone gain from sclerostin antibody administration.

Bone

Avec: Crystal Korff , Michele Adaway , Emily G Atkinson , Daniel J Horan , Angela Klunk , Brandy Suarez Silva , Teresita Bellido , Lilian I Plotkin , Alexander G Robling , Joseph P Bidwell

Loss-of-function

JBMR plus

Avec: Mizuho Kittaka , Noriyoshi Mizuno , Hiroyuki Morino , Tetsuya Yoshimoto , Tianli Zhu , Sheng Liu , Ziyi Wang , Kotoe Mayahara , Kyohei Iio , Kaori Kondo , Toshio Kondo , Tatsuhide Hayashi , Sarah Coghlan , Yayoi Teno , Andrew Anh Phung Doan , Marcus Levitan , Roy B Choi , Shinji Matsuda , Kazuhisa Ouhara , Jun Wan , Annelise M Cassidy , Stephane Pelletier , Sheela Nampoothiri , Andoni J Urtizberea , Alexander G Robling , Mitsuaki Ono , Hideshi Kawakami , Ernst J Reichenberger , Yasuyoshi Ueki

Improving Bone Health by Optimizing the Anabolic Action of Wnt Inhibitor Multitargeting.

JBMR plus

Avec: Roy B Choi , Whitney A Bullock , April M Hoggatt , Gabriela G Loots , Damian C Genetos , Alexander G Robling

The effect of overexpression of Lrp5 on orthodontic tooth movement.

Orthodontics & craniofacial research

Avec: Robert Holland , Carol Bain , Rawan S Alrasheed , Alexander G Robling , Achint Utreja

YAP and TAZ Mediate Osteocyte Perilacunar/Canalicular Remodeling.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Avec: Christopher D Kegelman , Jennifer C Coulombe , Kelsey M Jordan , Daniel J Horan , Ling Qin , Alexander G Robling , Virginia L Ferguson , Teresita M Bellido , Joel D Boerckel

Lrp4 Mediates Bone Homeostasis and Mechanotransduction through Interaction with Sclerostin In Vivo.

iScience

Avec: Whitney A Bullock , April M Hoggatt , Daniel J Horan , Andrew J Elmendorf , Amy Y Sato , Teresita Bellido , Gabriela G Loots , Fredrick M Pavalko , Alexander G Robling

Differential changes in bone strength of two inbred mouse strains following administration of a sclerostin-neutralizing antibody during growth.

PloS one

Avec: Noah J Mathis , Emily N Adaniya , Lauren M Smith , Alexander G Robling , Karl J Jepsen , Stephen H Schlecht

Targeting Sclerostin and Dkk1 at Optimized Proportions of Low-Dose Antibody Achieves Similar Skeletal Benefits to Higher-Dose Sclerostin Targeting in the Mature Adult and Aged Skeleton.

Aging and disease

Avec: Roy B Choi , April M Hoggatt , Daniel J Horan , Emily Z Rogers , Jung Min Hong , Alexander G Robling

Conditional Loss of Nmp4 in Mesenchymal Stem Progenitor Cells Enhances PTH-Induced Bone Formation.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Avec: Emily G Atkinson , Michele Adaway , Daniel J Horan , Crystal Korff , Angela Klunk , Ashley L Orr , Katherine Ratz , Teresita Bellido , Lilian I Plotkin , Alexander G Robling , Joseph P Bidwell

Réseau de co-auteurs

Daniel J Horan 16 collaborations

Whitney A Bullock 11 collaborations

Roy B Choi 8 collaborations

April M Hoggatt 7 collaborations

Matthew L Warman 7 collaborations

Gabriela G Loots 5 collaborations

Michele Adaway 5 collaborations

Angela Klunk 5 collaborations

Kyung-Eun Lim 5 collaborations

Hiroki Yokota 4 collaborations

Steven Hann 4 collaborations

Joseph P Bidwell 4 collaborations

Karl J Lewis 3 collaborations

William R Thompson 3 collaborations

Emily G Atkinson 3 collaborations

Ronald C Wek 3 collaborations

Joseph M Wallace 3 collaborations

Carmella Evans-Molina 3 collaborations

Lynda F Bonewald 3 collaborations

Bart O Williams 3 collaborations

Emily Z Pemberton 3 collaborations

Jung Min Hong 3 collaborations

Crystal Korff 3 collaborations

Teresita Bellido 3 collaborations

Aimy Sebastian 2 collaborations

Fredrick M Pavalko 2 collaborations

Christian S Wright 2 collaborations

Robert N Bone 2 collaborations

Aydin Jalali 2 collaborations

Andy Chen 2 collaborations

Shengzhi Liu 2 collaborations

Bai-Yan Li 2 collaborations

Yunlong Liu 2 collaborations

Deepak Vashishth 2 collaborations

Mizuho Kittaka 2 collaborations

Tetsuya Yoshimoto 2 collaborations

Yayoi Teno 2 collaborations

Yasuyoshi Ueki 2 collaborations

Sheng Liu 2 collaborations

Jun Wan 2 collaborations

Gabrielle E Foxa 2 collaborations

Xi He 2 collaborations

Emily Z Rogers 2 collaborations

Ugur M Ayturk 2 collaborations

Lilian I Plotkin 2 collaborations

Frederick M Pavalko 2 collaborations

Mary C Farach-Carson 1 collaboration

Joseph Bidwell 1 collaboration

Sarah A Tersey 1 collaboration

Amy Creecy 1 collaboration

Feifei Jiang 1 collaboration

Chie Deguchi 1 collaboration

Rika Kondo 1 collaboration

Kazumasa Minami 1 collaboration

Takashi Horiuchi 1 collaboration

Jie Chen 1 collaboration

Shannon Kaupp 1 collaboration

Dan J Horan 1 collaboration

Henry A Feldman 1 collaboration

Christina M Jacobsen 1 collaboration

Yu Shao 1 collaboration

Emily Wichern 1 collaboration

Paul J Childress 1 collaboration

Jagannath Misra 1 collaboration

David B Burr 1 collaboration

Amber L Mosley 1 collaboration

Nickolay Brustovetsky 1 collaboration

James Hamilton 1 collaboration

Kylie Jacobs 1 collaboration

Keith R Stayrook 1 collaboration

Matthew R Allen 1 collaboration

Caitlin Resendes 1 collaboration

Benlian Gao 1 collaboration

Ginger L Milne 1 collaboration

Krishnakali Dasgupta 1 collaboration

Samantha Lessard 1 collaboration

Megan E Fowler 1 collaboration

Marcus E Levitan 1 collaboration

Rina Urata 1 collaboration

Yixia Xie 1 collaboration

Yukiko Kitase 1 collaboration

Matthew Prideaux 1 collaboration

Sarah L Dallas 1 collaboration

Rafiou Agoro 1 collaboration

Intawat Nookaew 1 collaboration

Megan L Noonan 1 collaboration

Yamil G Marambio 1 collaboration

Wennan Chang 1 collaboration

Hongyu Gao 1 collaboration

Lainey M Hibbard 1 collaboration

Corinne E Metzger 1 collaboration

Daniel Horan 1 collaboration

Xiaoling Xuei 1 collaboration

Chi Zhang 1 collaboration

Kenneth E White 1 collaboration

Connor J Cunningham 1 collaboration

Kevin A Maupin 1 collaboration

Paul Childress 1 collaboration

Alexander Brinker 1 collaboration

Faisal Khan 1 collaboration

Irushi Abeysekera 1 collaboration

Izath Nizeet Aguilar 1 collaboration

David J Olivos 1 collaboration

Gremah Adam 1 collaboration

Michael K Savaglio 1 collaboration

Venkateswaran Ganesh 1 collaboration

Riley Gorden 1 collaboration

Rachel Mannfeld 1 collaboration

Elliott Beckner 1 collaboration

Nabarun Chakraborty 1 collaboration

Aarti Gautam 1 collaboration

Rasha Hammamieh 1 collaboration

Melissa A Kacena 1 collaboration

Yao Fan 1 collaboration

Xinyu Zhao 1 collaboration

Meghana Teli 1 collaboration

Yunxia Guo 1 collaboration

Fangjia Li 1 collaboration

Junrui Li 1 collaboration

Amanda Siegel 1 collaboration

Lianxiang Yang 1 collaboration

Jing Liu 1 collaboration

Sungsoo Na 1 collaboration

Mangilal Agarwal 1 collaboration

Harikrishna Nakshatri 1 collaboration

Austin M Reilly 1 collaboration

Shijun Yan 1 collaboration

Menghao Huang 1 collaboration

Surabhi D Abhyankar 1 collaboration

Jason M Conley 1 collaboration

Natalie D Stull 1 collaboration

Hyun C Roh 1 collaboration

Aaron C Ericsson 1 collaboration

Xiaocheng C Dong 1 collaboration

Hongxia Ren 1 collaboration

Ye Liu 1 collaboration

Lisa M Turner 1 collaboration

Tao Yang 1 collaboration

Xinjun Zhang 1 collaboration

Matt Prideaux 1 collaboration

Alberto Smargiassi 1 collaboration

Gang Peng 1 collaboration

Marco Brotto 1 collaboration

Aina He 1 collaboration

Songhai Tian 1 collaboration

Oded Kopper 1 collaboration

Peng Chen 1 collaboration

Roderick T Bronson 1 collaboration

Ren Sheng 1 collaboration

Hao Wu 1 collaboration

Lufei Sui 1 collaboration

Kun Zhou 1 collaboration

Liang Tao 1 collaboration

Quan Wu 1 collaboration

Yujing Huang 1 collaboration

Zan Shen 1 collaboration

Sen Han 1 collaboration

Xueqing Chen 1 collaboration

Hong Chen 1 collaboration

Rongsheng Jin 1 collaboration

Hans Clevers 1 collaboration

Dongxi Xiang 1 collaboration

Zhe Li 1 collaboration

Min Dong 1 collaboration

Cassandra R Diegel 1 collaboration

Jennifer C W Hu 1 collaboration

Casey J Droscha 1 collaboration

Zachary B Madaj 1 collaboration

Isaac Izaguirre 1 collaboration

Vai Vivarium And Transgenics Core 1 collaboration

Noorulain Paracha 1 collaboration

Bohdan Pidhaynyy 1 collaboration

Terry L Dowd 1 collaboration

Roy B-J Choi 1 collaboration

Anthony B Firulli 1 collaboration

Kyung Shin Kang 1 collaboration

Angela Bruzzaniti 1 collaboration

Xin Yi 1 collaboration

Daenique H A Jengelley 1 collaboration

Meijing Wang 1 collaboration

Ashok Narasimhan 1 collaboration

Joseph E Rupert 1 collaboration

Andrew R Young 1 collaboration

Xiaoling Zhong 1 collaboration

Leonidas G Koniaris 1 collaboration

Teresa A Zimmers 1 collaboration

Emily Atkinson 1 collaboration

Emily K Anderson-Baucum 1 collaboration

Brandy Suarez Silva 1 collaboration

Noriyoshi Mizuno 1 collaboration

Hiroyuki Morino 1 collaboration

Tianli Zhu 1 collaboration

Ziyi Wang 1 collaboration

Kotoe Mayahara 1 collaboration

Kyohei Iio 1 collaboration

Kaori Kondo 1 collaboration

Toshio Kondo 1 collaboration

Tatsuhide Hayashi 1 collaboration

Sarah Coghlan 1 collaboration

Andrew Anh Phung Doan 1 collaboration

Marcus Levitan 1 collaboration

Shinji Matsuda 1 collaboration

Kazuhisa Ouhara 1 collaboration

Annelise M Cassidy 1 collaboration

Stephane Pelletier 1 collaboration

Sheela Nampoothiri 1 collaboration

Andoni J Urtizberea 1 collaboration

Mitsuaki Ono 1 collaboration

Hideshi Kawakami 1 collaboration

Ernst J Reichenberger 1 collaboration

Damian C Genetos 1 collaboration

Robert Holland 1 collaboration

Carol Bain 1 collaboration

Rawan S Alrasheed 1 collaboration

Achint Utreja 1 collaboration

Christopher D Kegelman 1 collaboration

Jennifer C Coulombe 1 collaboration

Kelsey M Jordan 1 collaboration

Ling Qin 1 collaboration

Virginia L Ferguson 1 collaboration

Teresita M Bellido 1 collaboration

Joel D Boerckel 1 collaboration

Andrew J Elmendorf 1 collaboration

Amy Y Sato 1 collaboration

Noah J Mathis 1 collaboration

Emily N Adaniya 1 collaboration

Lauren M Smith 1 collaboration

Karl J Jepsen 1 collaboration

Stephen H Schlecht 1 collaboration

Cristine Donham 1 collaboration

Betsabel Chicana 1 collaboration

Asmaa Mohamed 1 collaboration

Sonny Elizaldi 1 collaboration

Michael Chi 1 collaboration

Brian Freeman 1 collaboration

Alberto Millan 1 collaboration

Deepa K Murugesh 1 collaboration

Nicholas R Hum 1 collaboration

Jennifer O Manilay 1 collaboration

Rong Huang 1 collaboration

Abhinav R Balu 1 collaboration

Kristin H Molitoris 1 collaboration

James P White 1 collaboration

Gurpreet S Baht 1 collaboration

Ashley L Orr 1 collaboration

Katherine Ratz 1 collaboration