Enhancement of the Auditory Late Response (N1-P2) by Presentation of Stimuli From an Unexpected Location.
Acoustic Stimulation
/ methods
Adolescent
Adult
Auditory Cortex
/ physiology
Auditory Perception
/ physiology
Electroencephalography
Evoked Potentials, Auditory, Brain Stem
/ physiology
Female
Follow-Up Studies
Healthy Volunteers
Humans
Male
Prospective Studies
Reaction Time
/ physiology
Young Adult
Journal
Journal of the American Academy of Audiology
ISSN: 2157-3107
Titre abrégé: J Am Acad Audiol
Pays: United States
ID NLM: 9114646
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
pubmed:
24
10
2018
medline:
10
9
2020
entrez:
24
10
2018
Statut:
ppublish
Résumé
Passive electrophysiological protocols, such as the middle latency response and speech auditory brainstem response, are often advocated in the objective assessment of central auditory processing disorder (CAPD). However, few established electrophysiological protocols exist for CAPD assessment that have patients participate in active tasks which more closely approximate real-world listening. To this end, the present study used a discrimination task (i.e., oddball paradigm) to measure an enhancement of the auditory late response (N1-P2) that occurs when participants direct their auditory attention toward speech arising from an unexpected spatial location. To establish whether N1-P2 is enhanced when auditory attention is directed toward an unexpected location during a two-word discrimination task. In addition, it was also investigated whether any enhancements in this response were contingent on the stimulus being counted as part of the oddball paradigm. Prospective study with a repeated measures design. Ten normal hearing adults, with an age range of 18-24 years. The N1 and P2 latencies and peak-to-peak amplitudes were recorded during a P300 paradigm. A series of repeated measures of analysis of variance and a correlation analysis was performed. There was a significant effect of stimulus location, in which words arising from the unexpected location showed a larger N1-P2 peak-to-peak amplitude and an earlier N1 latency. This effect was seen regardless of whether or not participants had to count the word total in memory. These findings suggest that spatial enhancement of the N1-P2 is a fairly robust phenomenon in normal hearing adult listeners. Additional studies are needed to determine whether this enhancement is absent or reduced in patients with CAPD.
Sections du résumé
BACKGROUND
Passive electrophysiological protocols, such as the middle latency response and speech auditory brainstem response, are often advocated in the objective assessment of central auditory processing disorder (CAPD). However, few established electrophysiological protocols exist for CAPD assessment that have patients participate in active tasks which more closely approximate real-world listening. To this end, the present study used a discrimination task (i.e., oddball paradigm) to measure an enhancement of the auditory late response (N1-P2) that occurs when participants direct their auditory attention toward speech arising from an unexpected spatial location.
PURPOSE
To establish whether N1-P2 is enhanced when auditory attention is directed toward an unexpected location during a two-word discrimination task. In addition, it was also investigated whether any enhancements in this response were contingent on the stimulus being counted as part of the oddball paradigm.
RESEARCH DESIGN
Prospective study with a repeated measures design.
STUDY SAMPLE
Ten normal hearing adults, with an age range of 18-24 years.
DATA COLLECTION AND ANALYSIS
The N1 and P2 latencies and peak-to-peak amplitudes were recorded during a P300 paradigm. A series of repeated measures of analysis of variance and a correlation analysis was performed.
RESULTS
There was a significant effect of stimulus location, in which words arising from the unexpected location showed a larger N1-P2 peak-to-peak amplitude and an earlier N1 latency. This effect was seen regardless of whether or not participants had to count the word total in memory.
CONCLUSIONS
These findings suggest that spatial enhancement of the N1-P2 is a fairly robust phenomenon in normal hearing adult listeners. Additional studies are needed to determine whether this enhancement is absent or reduced in patients with CAPD.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
451-458Informations de copyright
American Academy of Audiology.