Diagnosis of Pulmonary Hypertension with Cardiac MRI: Derivation and Validation of Regression Models.


Journal

Radiology
ISSN: 1527-1315
Titre abrégé: Radiology
Pays: United States
ID NLM: 0401260

Informations de publication

Date de publication:
01 2019
Historique:
pubmed: 24 10 2018
medline: 12 10 2019
entrez: 24 10 2018
Statut: ppublish

Résumé

Purpose To derive and test multiparametric cardiac MRI models for the diagnosis of pulmonary hypertension (PH). Materials and Methods Images and patient data from consecutive patients suspected of having PH who underwent cardiac MRI and right-sided heart catheterization (RHC) between 2012 and 2016 were retrospectively reviewed. Of 2437 MR images identified, 603 fit the inclusion criteria. The mean patient age was 61 years (range, 18-88 years; mean age of women, 60 years [range, 18-84 years]; mean age of men, 62 years [range, 22-88 years]). In the first 300 patients (derivation cohort), cardiac MRI metrics that showed correlation with mean pulmonary arterial pressure (mPAP) were used to create a regression algorithm. The performance of the model was assessed in the 303-patient validation cohort by using receiver operating characteristic (ROC) and χ

Identifiants

pubmed: 30351254
doi: 10.1148/radiol.2018180603
pmc: PMC6314564
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

61-68

Subventions

Organisme : Medical Research Council
ID : MR/M008894/1
Pays : United Kingdom
Organisme : British Heart Foundation
ID : SP/14/6/31350
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_16058
Pays : United Kingdom
Organisme : Department of Health
ID : NIHR-RP-R3-12-027
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 205188/Z/16/Z
Pays : United Kingdom

Commentaires et corrections

Type : CommentIn

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Auteurs

Christopher S Johns (CS)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

David G Kiely (DG)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

Smitha Rajaram (S)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

Catherine Hill (C)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

Steven Thomas (S)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

Kavitasagary Karunasaagarar (K)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

Pankaj Garg (P)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

Neil Hamilton (N)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

Roshni Solanki (R)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

David A Capener (DA)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

Charles Elliot (C)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

Ian Sabroe (I)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

Athanasios Charalamopopoulos (A)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

Robin Condliffe (R)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

James M Wild (JM)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

Andrew J Swift (AJ)

From the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.

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