Transcatheter aortic valve implantation utilizing a non-occlusive balloon for predilatation.


Journal

International journal of cardiology
ISSN: 1874-1754
Titre abrégé: Int J Cardiol
Pays: Netherlands
ID NLM: 8200291

Informations de publication

Date de publication:
15 Jan 2019
Historique:
received: 11 05 2018
revised: 03 10 2018
accepted: 17 10 2018
pubmed: 28 10 2018
medline: 20 7 2019
entrez: 28 10 2018
Statut: ppublish

Résumé

Balloon aortic valvuloplasty (BAV) is routinely performed preceding transcatheter aortic valve implantation (TAVI). Among risks inherent in BAV is low cardiac output due to rapid ventricular pacing (RVP), especially in patients with severely impaired left ventricular function. We herein report early experience utilizing a non-occlusive balloon for BAV (TrueFlow™, BARD, Peripheral Vascular, Tempe, AZ, US), which does not require RVP. Between 11/2016 and 10/2017, 27 consecutive patients received TAVI using a non-occlusive balloon valvuloplasty catheter for predilatation and a self-expandable transcatheter heart valve (77.8% female, 81.7 ± 6.6 years, logEuroSCORE I 15.8 ± 10.3%, STS Prom Score 2.5 ± 0.5%). Hemodynamic measurements and acute outcome data were analyzed according to updated Valve Academic Research Consortium definitions. Procedure time, fluoroscopy time and amount of contrast agent were 74.5 ± 17.4 min, 16.7 ± 6.9 min and 156.9 ± 92.7 ml. Device success and early combined safety were 100% and 92.6% (25/27). Effective BAV without RVP after the first inflation was achieved in 92.6% of the patients (25/27). Continuous recording of hemodynamics documented no relevant systemic pressure drop during BAV. Postdilatation with a regular balloon was required in 10/27 patients. No death was observed during 30-day follow-up. Resultant mean transvalvular gradient was 6.0 ± 3.5 mm Hg. In one patient a moderate paravalvular leakage was seen. In this series of TAVI utilizing a novel non-occlusive balloon, safety and efficacy were demonstrated. Adequate predilatation was achieved in all cases without need for RVP and with stable hemodynamics. These results will have to be confirmed in larger patient cohorts.

Sections du résumé

BACKGROUND BACKGROUND
Balloon aortic valvuloplasty (BAV) is routinely performed preceding transcatheter aortic valve implantation (TAVI). Among risks inherent in BAV is low cardiac output due to rapid ventricular pacing (RVP), especially in patients with severely impaired left ventricular function. We herein report early experience utilizing a non-occlusive balloon for BAV (TrueFlow™, BARD, Peripheral Vascular, Tempe, AZ, US), which does not require RVP.
METHODS METHODS
Between 11/2016 and 10/2017, 27 consecutive patients received TAVI using a non-occlusive balloon valvuloplasty catheter for predilatation and a self-expandable transcatheter heart valve (77.8% female, 81.7 ± 6.6 years, logEuroSCORE I 15.8 ± 10.3%, STS Prom Score 2.5 ± 0.5%). Hemodynamic measurements and acute outcome data were analyzed according to updated Valve Academic Research Consortium definitions.
RESULTS RESULTS
Procedure time, fluoroscopy time and amount of contrast agent were 74.5 ± 17.4 min, 16.7 ± 6.9 min and 156.9 ± 92.7 ml. Device success and early combined safety were 100% and 92.6% (25/27). Effective BAV without RVP after the first inflation was achieved in 92.6% of the patients (25/27). Continuous recording of hemodynamics documented no relevant systemic pressure drop during BAV. Postdilatation with a regular balloon was required in 10/27 patients. No death was observed during 30-day follow-up. Resultant mean transvalvular gradient was 6.0 ± 3.5 mm Hg. In one patient a moderate paravalvular leakage was seen.
CONCLUSIONS CONCLUSIONS
In this series of TAVI utilizing a novel non-occlusive balloon, safety and efficacy were demonstrated. Adequate predilatation was achieved in all cases without need for RVP and with stable hemodynamics. These results will have to be confirmed in larger patient cohorts.

Identifiants

pubmed: 30366854
pii: S0167-5273(18)33079-1
doi: 10.1016/j.ijcard.2018.10.059
pii:
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

65-69

Informations de copyright

Copyright © 2018 Elsevier B.V. All rights reserved.

Auteurs

Yvonne Schneeberger (Y)

Department of Cardiovascular Surgery, University Heart Center Hamburg, Germany. Electronic address: y.schneeberger@uke.de.

Andreas Schaefer (A)

Department of Cardiovascular Surgery, University Heart Center Hamburg, Germany.

Niklas Schofer (N)

Department of General and Interventional Cardiology, University Heart Center Hamburg, Germany.

Miriam Silaschi (M)

Department of Cardiac Surgery, University Hospital Halle (Saale), Germany.

Florian Deuschl (F)

Department of General and Interventional Cardiology, University Heart Center Hamburg, Germany.

Stefan Blankenberg (S)

Department of General and Interventional Cardiology, University Heart Center Hamburg, Germany.

Hermann Reichenspurner (H)

Department of Cardiovascular Surgery, University Heart Center Hamburg, Germany.

Hendrik Treede (H)

Department of Cardiac Surgery, University Hospital Halle (Saale), Germany.

Ulrich Schäfer (U)

Department of General and Interventional Cardiology, University Heart Center Hamburg, Germany.

Efstratios I Charitos (EI)

Department of Cardiac Surgery, University Hospital Halle (Saale), Germany.

Lenard Conradi (L)

Department of Cardiovascular Surgery, University Heart Center Hamburg, Germany.

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