Predictors of cardiovascular outcome and rehospitalization in elderly patients with heart failure.


Journal

European journal of clinical investigation
ISSN: 1365-2362
Titre abrégé: Eur J Clin Invest
Pays: England
ID NLM: 0245331

Informations de publication

Date de publication:
Feb 2019
Historique:
received: 26 04 2018
revised: 22 10 2018
accepted: 23 10 2018
pubmed: 29 10 2018
medline: 23 7 2019
entrez: 29 10 2018
Statut: ppublish

Résumé

Heart failure (HF) is a major public health problem and represents the only cardiac disease continuing to increase in prevalence, in particular among elderly patients. The frequent rehospitalizations have a negative impact on quality of life of patients with HF, constituting a substantial cost for patients and the health system. The aim of this review was to look into biochemical, echocardiographic and socioeconomical parameters as predictors of clinical outcomes and rehospitalizations. This narrative review is based on the material searched for and obtained via PubMed from January 2000 up to March 2018. The search terms we used were as follows: "elderly, heart failure, cardiovascular" in combination with "biomarker, echocardiography and hospitalization." This review analyses the potential predictive role of biochemical and echocardiographic and socioeconomical parameters on clinical outcomes (particularly cardiovascular) and hospital readmissions in patients with chronic HF. We focused on risk stratification of elderly patients with HF, who constitute a category of frail subjects at higher risk for readmission to hospital. In elderly subjects with chronic HF, the risk stratification could benefit of a multiparametric approach combining biochemical, echocardiographic, demographic and socioeconomical parameters, thus ensuring a better quality of life and at the same time a better allocation of financial resources.

Sections du résumé

BACKGROUND BACKGROUND
Heart failure (HF) is a major public health problem and represents the only cardiac disease continuing to increase in prevalence, in particular among elderly patients. The frequent rehospitalizations have a negative impact on quality of life of patients with HF, constituting a substantial cost for patients and the health system. The aim of this review was to look into biochemical, echocardiographic and socioeconomical parameters as predictors of clinical outcomes and rehospitalizations.
METHODS METHODS
This narrative review is based on the material searched for and obtained via PubMed from January 2000 up to March 2018. The search terms we used were as follows: "elderly, heart failure, cardiovascular" in combination with "biomarker, echocardiography and hospitalization."
RESULTS RESULTS
This review analyses the potential predictive role of biochemical and echocardiographic and socioeconomical parameters on clinical outcomes (particularly cardiovascular) and hospital readmissions in patients with chronic HF. We focused on risk stratification of elderly patients with HF, who constitute a category of frail subjects at higher risk for readmission to hospital.
CONCLUSIONS CONCLUSIONS
In elderly subjects with chronic HF, the risk stratification could benefit of a multiparametric approach combining biochemical, echocardiographic, demographic and socioeconomical parameters, thus ensuring a better quality of life and at the same time a better allocation of financial resources.

Identifiants

pubmed: 30368802
doi: 10.1111/eci.13044
doi:

Substances chimiques

Biomarkers 0
Natriuretic Peptides 0
Parathyroid Hormone 0
Troponin 0
Vitamin D 1406-16-2
C-Reactive Protein 9007-41-4

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e13044

Informations de copyright

© 2018 Stichting European Society for Clinical Investigation Journal Foundation.

Auteurs

Gian M Rosa (GM)

Clinic of Cardiovascular Diseases, University of Genoa, Genoa, Italy.
IRCCS Ospedale Policlinico San Martino Genoa - Italian Cardiovascular Network, Genoa, Italy.

Riccardo Scagliola (R)

Clinic of Cardiovascular Diseases, University of Genoa, Genoa, Italy.

Paola Ghione (P)

Clinic of Cardiovascular Diseases, University of Genoa, Genoa, Italy.

Alberto Valbusa (A)

IRCCS Ospedale Policlinico San Martino Genoa - Italian Cardiovascular Network, Genoa, Italy.

Claudio Brunelli (C)

Clinic of Cardiovascular Diseases, University of Genoa, Genoa, Italy.
IRCCS Ospedale Policlinico San Martino Genoa - Italian Cardiovascular Network, Genoa, Italy.

Federico Carbone (F)

Department of Internal Medicine, First Clinic of Internal Medicine, University of Genoa, Genoa, Italy.

Fabrizio Montecucco (F)

IRCCS Ospedale Policlinico San Martino Genoa - Italian Cardiovascular Network, Genoa, Italy.
Department of Internal Medicine, and Centre of Excellence for Biomedical Research (CEBR), First Clinic of Internal Medicine, University of Genoa, Genoa, Italy.

Fiammetta Monacelli (F)

IRCCS Ospedale Policlinico San Martino Genoa, Genoa, Italy.
Department of Internal Medicine, Geriatric Unit, University of Genoa, Genoa, Italy.

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Classifications MeSH