Cortical thickness and volume reductions in young adults with current suicidal ideation.
Neuroimaging
Precentral gyrus
Suicide
Journal
Journal of affective disorders
ISSN: 1573-2517
Titre abrégé: J Affect Disord
Pays: Netherlands
ID NLM: 7906073
Informations de publication
Date de publication:
15 02 2019
15 02 2019
Historique:
received:
11
03
2018
revised:
09
08
2018
accepted:
04
10
2018
pubmed:
6
11
2018
medline:
26
3
2019
entrez:
3
11
2018
Statut:
ppublish
Résumé
The extent to which observed differences in emotion processing and regulation neural circuitry in young adults with current suicidal ideation are paralleled by structural differences is unknown. We measured brain cortical thickness and gray and white matter volumes in 78 young adults aged 18-35: 35 with current suicidal ideation (SI) and 43 healthy controls (HC). The SI group, compared to HC, showed reduction in cortical thickness in the bilateral precentral gyri and diminished cortical volume in the left middle frontal gyrus. These regions are implicated in executive function, stress regulation, and emotion processing. We propose that these structural differences among the SI group could be contributing to suicidal thought patterns.
Identifiants
pubmed: 30388554
pii: S0165-0327(17)32602-2
doi: 10.1016/j.jad.2018.10.081
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
126-129Informations de copyright
Copyright © 2018 Elsevier B.V. All rights reserved.