Sex differences in national rates of repair of emergency abdominal aortic aneurysm.


Journal

The British journal of surgery
ISSN: 1365-2168
Titre abrégé: Br J Surg
Pays: England
ID NLM: 0372553

Informations de publication

Date de publication:
01 2019
Historique:
received: 18 06 2018
revised: 17 07 2018
accepted: 28 08 2018
pubmed: 6 11 2018
medline: 30 4 2019
entrez: 6 11 2018
Statut: ppublish

Résumé

The aim of this study was to assess the sex differences in both the rate and type of repair for emergency abdominal aortic aneurysm (AAA) in England. Hospital Episode Statistics (HES) data sets from April 2002 to February 2015 were obtained. Clinical and administrative codes were used to identify patients who underwent primary emergency definitive repair of ruptured or intact AAA, and patients with a diagnosis of AAA who died in hospital without repair. These three groups included all patients with a primary AAA who presented as an emergency. Sex differences between repair rates and type of surgery (endovascular aneurysm repair (EVAR) versus open repair) over time were examined. In total, 15 717 patients (83·3 per cent men) received emergency surgical intervention for ruptured AAA and 10 276 (81·2 per cent men) for intact AAA; 12 767 (62·0 per cent men) died in hospital without attempted repair. The unadjusted odds ratio for no repair in women versus men was 2·88 (95 per cent c.i. 2·75 to 3·02). Women undergoing repair of ruptured AAA were older and had a higher in-hospital mortality rate (50·0 versus 41·0 per cent for open repair; 30·9 versus 23·5 per cent for EVAR). After adjustment for age, deprivation and co-morbidities, the odds ratio for no repair in women versus men was 1·34 (1·28 to 1·40). The in-hospital mortality rate after emergency repair of an intact AAA was also higher among women. Women who present as an emergency with an AAA are less likely to undergo repair than men. Although some of this can be explained by differences in age and co-morbidities, the differences persist after case-mix adjustment.

Sections du résumé

BACKGROUND
The aim of this study was to assess the sex differences in both the rate and type of repair for emergency abdominal aortic aneurysm (AAA) in England.
METHODS
Hospital Episode Statistics (HES) data sets from April 2002 to February 2015 were obtained. Clinical and administrative codes were used to identify patients who underwent primary emergency definitive repair of ruptured or intact AAA, and patients with a diagnosis of AAA who died in hospital without repair. These three groups included all patients with a primary AAA who presented as an emergency. Sex differences between repair rates and type of surgery (endovascular aneurysm repair (EVAR) versus open repair) over time were examined.
RESULTS
In total, 15 717 patients (83·3 per cent men) received emergency surgical intervention for ruptured AAA and 10 276 (81·2 per cent men) for intact AAA; 12 767 (62·0 per cent men) died in hospital without attempted repair. The unadjusted odds ratio for no repair in women versus men was 2·88 (95 per cent c.i. 2·75 to 3·02). Women undergoing repair of ruptured AAA were older and had a higher in-hospital mortality rate (50·0 versus 41·0 per cent for open repair; 30·9 versus 23·5 per cent for EVAR). After adjustment for age, deprivation and co-morbidities, the odds ratio for no repair in women versus men was 1·34 (1·28 to 1·40). The in-hospital mortality rate after emergency repair of an intact AAA was also higher among women.
CONCLUSION
Women who present as an emergency with an AAA are less likely to undergo repair than men. Although some of this can be explained by differences in age and co-morbidities, the differences persist after case-mix adjustment.

Identifiants

pubmed: 30395361
doi: 10.1002/bjs.11006
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

82-89

Subventions

Organisme : Department of Health
ID : RP-PG-1210-12009
Pays : United Kingdom

Informations de copyright

© 2018 BJS Society Ltd Published by John Wiley & Sons Ltd.

Auteurs

A Aber (A)

School of Health and Related Research, University of Sheffield, Sheffield, UK.

T S Tong (TS)

School of Health and Related Research, University of Sheffield, Sheffield, UK.

J Chilcott (J)

School of Health and Related Research, University of Sheffield, Sheffield, UK.

P Thokala (P)

School of Health and Related Research, University of Sheffield, Sheffield, UK.

R Maheswaran (R)

School of Health and Related Research, University of Sheffield, Sheffield, UK.

S M Thomas (SM)

Sheffield Vascular Institute, Sheffield Teaching Hospitals, Sheffield, UK.

S Nawaz (S)

Sheffield Vascular Institute, Sheffield Teaching Hospitals, Sheffield, UK.

S Walters (S)

School of Health and Related Research, University of Sheffield, Sheffield, UK.

J Michaels (J)

School of Health and Related Research, University of Sheffield, Sheffield, UK.

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