Trends in Hospitalization and In-Hospital Mortality From VTE, 2007 to 2016, in China.
DVT
VTE
hospitalization rate
mortality
pulmonary embolism
Journal
Chest
ISSN: 1931-3543
Titre abrégé: Chest
Pays: United States
ID NLM: 0231335
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
received:
06
06
2018
revised:
07
10
2018
accepted:
29
10
2018
pubmed:
13
11
2018
medline:
16
11
2019
entrez:
13
11
2018
Statut:
ppublish
Résumé
VTE has emerged as a major public health problem. However, data on VTE burden in China are seldom reported. This study collected data on patients with a principal diagnosis of VTE, pulmonary embolism (PE), or DVT by using the International Classification of Diseases, 10th Revision, from 90 hospitals across China. The trends in hospitalization rates, mortality, length of stay (LOS), and comorbidities from 2007 to 2016 were analyzed. In total, 105,723 patients with VTE were identified. For patients with VTE, the age- and sex-adjusted hospitalization rate increased from 3.2 to 17.5 per 100,000 population, and in-hospital mortality decreased from 4.7% to 2.1% (P < .001). The mean LOS declined from 14 to 11 days (P < .001). In addition, the data in 2016 showed that the hospitalization rate of VTE was higher in elderly male patients (male patients vs female patients, 155.3 vs 125.4 per 100,000 population in patients aged ≥ 85 years; P < .001) and in northern China (north vs south, 18.4 vs 13.4 per 100,000 population; P < .001). Higher mortality rates were found in patients with cancer and Charlson Comorbidity Index scores > 2. Similar trends were also observed in patients with PE and those with DVT. The hospitalization rate in China was much lower than that of the United States or selected sites in Canada and Europe, the LOS was much longer, and the in-hospital mortality rates were similar. The hospitalization rates of VTE increased steadily, and the mortality declined. This study provides important information on the disease burden of VTE in China.
Sections du résumé
BACKGROUND
VTE has emerged as a major public health problem. However, data on VTE burden in China are seldom reported.
METHODS
This study collected data on patients with a principal diagnosis of VTE, pulmonary embolism (PE), or DVT by using the International Classification of Diseases, 10th Revision, from 90 hospitals across China. The trends in hospitalization rates, mortality, length of stay (LOS), and comorbidities from 2007 to 2016 were analyzed.
RESULTS
In total, 105,723 patients with VTE were identified. For patients with VTE, the age- and sex-adjusted hospitalization rate increased from 3.2 to 17.5 per 100,000 population, and in-hospital mortality decreased from 4.7% to 2.1% (P < .001). The mean LOS declined from 14 to 11 days (P < .001). In addition, the data in 2016 showed that the hospitalization rate of VTE was higher in elderly male patients (male patients vs female patients, 155.3 vs 125.4 per 100,000 population in patients aged ≥ 85 years; P < .001) and in northern China (north vs south, 18.4 vs 13.4 per 100,000 population; P < .001). Higher mortality rates were found in patients with cancer and Charlson Comorbidity Index scores > 2. Similar trends were also observed in patients with PE and those with DVT. The hospitalization rate in China was much lower than that of the United States or selected sites in Canada and Europe, the LOS was much longer, and the in-hospital mortality rates were similar.
CONCLUSIONS
The hospitalization rates of VTE increased steadily, and the mortality declined. This study provides important information on the disease burden of VTE in China.
Identifiants
pubmed: 30419233
pii: S0012-3692(18)32721-1
doi: 10.1016/j.chest.2018.10.040
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
342-353Investigateurs
Jin Zhang
(J)
Peng Zhang
(P)
Yimin Mao
(Y)
Xiaohong Yang
(X)
Xiaomao Xu
(X)
Guoguang Xia
(G)
Rui Zheng
(R)
Yuan Gao
(Y)
Guangfa Zhu
(G)
Chenxi Zhu
(C)
Yingyun Fu
(Y)
Hong Chen
(H)
Fangfei Yu
(F)
Jiulong Kuang
(J)
Ziqiang Li
(Z)
Zhe Cheng
(Z)
Rui Wu
(R)
Zhaozhong Cheng
(Z)
Li Tong
(L)
Yanwen Jiang
(Y)
Jie Sun
(J)
Qixia Xu
(Q)
Huiyun Pan
(H)
Lihong Wang
(L)
Mian Zeng
(M)
Yanzhu Chen
(Y)
Chunxiao Yu
(C)
Jing Hua
(J)
Yongjun Tang
(Y)
Yingqun Ji
(Y)
Jun An
(J)
Yongxiang Zhang
(Y)
Yanyan Ding
(Y)
Wei Zhang
(W)
Xiaomai Wu
(X)
Wenshu Chai
(W)
Jing Li
(J)
Qun Yi
(Q)
Haixia Wang
(H)
Xiaoju Chen
(X)
Aizhen Zhang
(A)
Jun Han
(J)
Kejing Ying
(K)
Xiaoling Xu
(X)
Zhihong Shi
(Z)
Jiaolin Sun
(J)
Qiuliang Zhao
(Q)
Guangjie Liu
(G)
Jie Zhuo
(J)
Guochao Shi
(G)
Yongjie Ding
(Y)
Zhihong He
(Z)
Zhe Lang
(Z)
Xiaoyun Hu
(X)
Fangfang Fan
(F)
Hong Liu
(H)
Guohua Sun
(G)
Guoqiang Xing
(G)
Yingqi Zhang
(Y)
Guanli Su
(G)
Jixiang Ni
(J)
Tianming Zhao
(T)
Jun Wang
(J)
Nuofu Zhang
(N)
Simin Qin
(S)
Songping Huang
(S)
Qinghua Xu
(Q)
Yunqiu Li
(Y)
Qian Liu
(Q)
Qi Wu
(Q)
Li Li
(L)
Xisheng Chen
(X)
Zhiwei Niu
(Z)
Jianan Huang
(J)
Daxiong Zeng
(D)
Yadong Yuan
(Y)
Qian Tian
(Q)
Jian Zhang
(J)
Xinpeng Han
(X)
Jingping Yang
(J)
Baoying Bo
(B)
Yurong Huang
(Y)
Qian Luo
(Q)
Guifen Pang
(G)
Hongfei Zheng
(H)
Ping Zhang
(P)
Ruhong Xu
(R)
Yunfeng Zhang
(Y)
Songshi Ni
(S)
Shengqing Li
(S)
Yi Gong
(Y)
Jie Zhang
(J)
Ling Zhu
(L)
Shuyue Xia
(S)
Yule Chang
(Y)
Jian Zhang
(J)
Xinpeng Han
(X)
Yadong Yuan
(Y)
Qian Tian
(Q)
Hongyu Zhang
(H)
Xia Xu
(X)
Yiwen Zhang
(Y)
Jingjing Pan
(J)
Zhiqiang Qin
(Z)
Miaochan Lao
(M)
Jing Li
(J)
Zhihong Liu
(Z)
Qin Luo
(Q)
Jun Wang
(J)
Ning Wang
(N)
Huiqin Yang
(H)
Xiaoli Tang
(X)
Xiaomin Bai
(X)
Yanwei Chen
(Y)
Dan Han
(D)
Shasha Shen
(S)
Chen Jin
(C)
Yanping Ye
(Y)
Lijun Suo
(L)
Xiaoying Huang
(X)
Jialie Wang
(J)
Xiangyan Zhang
(X)
Guoru Yang
(G)
Guohua Yu
(G)
Shudong Zhang
(S)
Yinlou Yang
(Y)
Jiangtao Cheng
(J)
Jie Duo
(J)
Hong Zhang
(H)
Ping Wang
(P)
Yueyue Li
(Y)
Ping Wang
(P)
Changcheng Guo
(C)
Tao Bian
(T)
Shaoxi Cai
(S)
Zhenshun Cheng
(Z)
Ting Wang
(T)
Yong He
(Y)
Wentong Huang
(W)
Chengying Liu
(C)
Hongda Zhao
(H)
Fenglin Tu
(F)
Youming Zhu
(Y)
Guizhen Tian
(G)
Informations de copyright
Copyright © 2018 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.