Inhibition of nuclear thioredoxin aggregation attenuates PM

Active Transport, Cell Nucleus Air Pollutants Bronchi / pathology Cell Line Cell Nucleus / metabolism Cytokines / metabolism Epithelial Cells / metabolism Gene Expression Regulation Humans Inflammation / metabolism Inflammation Mediators / metabolism NF-E2-Related Factor 2 / genetics NF-kappa B / metabolism Particulate Matter / metabolism Protein Aggregation, Pathological Thioredoxins / metabolism Transcriptional Activation
Inflammation NF-κB Nrf2 PM(2.5) Trx

Journal

Free radical biology & medicine
ISSN: 1873-4596
Titre abrégé: Free Radic Biol Med
Pays: United States
ID NLM: 8709159

Informations de publication

Date de publication:
01 2019
Historique:
received: 14 09 2018
revised: 19 10 2018
accepted: 22 10 2018
pubmed: 14 11 2018
medline: 18 2 2020
entrez: 14 11 2018
Statut: ppublish

Résumé

Exposure to fine particulate matter (PM

Identifiants

DOI: 10.1016/j.freeradbiomed.2018.10.438 PMID: 30420332
pubmed: 30420332
pii: S0891-5849(18)31595-8
doi: 10.1016/j.freeradbiomed.2018.10.438
pii:
doi:

Substances chimiques

Air Pollutants 0
Cytokines 0
Inflammation Mediators 0
NF-E2-Related Factor 2 0
NF-kappa B 0
NFE2L2 protein, human 0
Particulate Matter 0
Thioredoxins 52500-60-4

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

206-214

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Zhonghui Zhu (Z)

Department of Occupational and Environmental Health, School of Public Health, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China.

Xiaowei Chen (X)

Department of Occupational and Environmental Health, School of Public Health, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China.

Jingping Sun (J)

Department of Occupational and Environmental Health, School of Public Health, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China.

Qiuyue Li (Q)

Department of Occupational and Environmental Health, School of Public Health, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China.

Ximeng Lian (X)

Department of Occupational and Environmental Health, School of Public Health, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China.

Siling Li (S)

Department of Occupational and Environmental Health, School of Public Health, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China.

Yan Wang (Y)

Department of Occupational and Environmental Health, School of Public Health, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China.

Lin Tian (L)

Department of Occupational and Environmental Health, School of Public Health, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China. Electronic address: tianlin@ccmu.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Métabolisme › Transport biologique › Transport des protéines › Transport nucléaire actif › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Polluants environnementaux › Polluants atmosphériques › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Appareil respiratoire › Poumon › Bronches › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Noyau de la cellule › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Cellules › Cellules épithéliales › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Facteurs biologiques › Médiateurs de l'inflammation › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à motif basique et à glissière à leucines › Facteur-2 apparenté à NF-E2 › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteur de transcription NF-kappa B › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Mélanges complexes › Matière particulaire › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Agrégation pathologique de protéines › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Thiorédoxines › Inhibition of nuclear thioredoxin aggregation...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Activation de la transcription › Inhibition of nuclear thioredoxin aggregation...