Pterostilbene alleviates hydrogen peroxide-induced oxidative stress via nuclear factor erythroid 2 like 2 pathway in mouse preimplantation embryos.
Animals
Antioxidants
/ pharmacology
Apoptosis
/ drug effects
Blastocyst
/ drug effects
Caspase 3
/ genetics
Embryo Culture Techniques
Female
Gene Expression
/ drug effects
Glutathione
/ analysis
Hydrogen Peroxide
/ pharmacology
In Situ Nick-End Labeling
Kelch-Like ECH-Associated Protein 1
/ physiology
Mice
NF-E2-Related Factor 2
/ drug effects
Oxidative Stress
/ drug effects
Proto-Oncogene Proteins c-bcl-2
/ genetics
Reactive Oxygen Species
/ analysis
Stilbenes
/ pharmacology
bcl-2-Associated X Protein
/ genetics
In vitro culture medium
Mouse embryo
Nuclear Factor Erythroid 2 like 2 (NFE2L2)
Oxidative stress
Pterostilbene
Journal
The Journal of reproduction and development
ISSN: 1348-4400
Titre abrégé: J Reprod Dev
Pays: Japan
ID NLM: 9438792
Informations de publication
Date de publication:
08 Feb 2019
08 Feb 2019
Historique:
pubmed:
16
11
2018
medline:
29
5
2019
entrez:
16
11
2018
Statut:
ppublish
Résumé
Pterostilbene (PTS) in blueberries is a phytoalexin with antioxidant properties. PTS exerts strong cytoprotective effects on various cells via Nuclear Factor Erythroid 2 like 2 (NFE2L2) pathway. We evaluated the antioxidant PTS treatment in mouse preimplantation embryos. In vitro culture media were supplemented with different concentrations of PTS. Treatment of zygotes with 0.25 μM PTS improved the development of day 4 blastocysts (P < 0.05). Moreover, H
Identifiants
pubmed: 30429414
doi: 10.1262/jrd.2018-089
pmc: PMC6379763
doi:
Substances chimiques
Antioxidants
0
Kelch-Like ECH-Associated Protein 1
0
NF-E2-Related Factor 2
0
Proto-Oncogene Proteins c-bcl-2
0
Reactive Oxygen Species
0
Stilbenes
0
bcl-2-Associated X Protein
0
pterostilbene
26R60S6A5I
Hydrogen Peroxide
BBX060AN9V
Caspase 3
EC 3.4.22.-
Glutathione
GAN16C9B8O
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
73-81Références
Theriogenology. 2000 Feb;53(3):761-71
pubmed: 10735042
J Biol Chem. 2001 Jun 22;276(25):22586-94
pubmed: 11316812
J Agric Food Chem. 2002 Jun 5;50(12):3453-7
pubmed: 12033810
Annu Rev Pharmacol Toxicol. 2005;45:51-88
pubmed: 15822171
Oncol Rep. 2006 Sep;16(3):617-24
pubmed: 16865264
Med Chem. 2006 May;2(3):275-85
pubmed: 16948474
J Pharm Pharmacol. 2006 Nov;58(11):1483-90
pubmed: 17132211
Free Radic Biol Med. 2007 Apr 15;42(8):1201-10
pubmed: 17382201
Phytother Res. 2008 Feb;22(2):169-79
pubmed: 17726731
Reproduction. 2008 Feb;135(2):141-50
pubmed: 18239045
Chem Res Toxicol. 2008 Jul;21(7):1375-83
pubmed: 18512965
Mol Nutr Food Res. 2008 Jun;52 Suppl 1:S62-70
pubmed: 18551458
Reprod Domest Anim. 2008 Oct;43 Suppl 4:44-50
pubmed: 18803756
Mol Reprod Dev. 2009 May;76(5):490-500
pubmed: 19090011
Biomed Chromatogr. 2009 Dec;23(12):1308-15
pubmed: 19488981
Reprod Domest Anim. 2010 Dec;45(6):1118-21
pubmed: 19515031
Toxicol In Vitro. 2010 Jun;24(4):1215-28
pubmed: 20152895
Cancer Chemother Pharmacol. 2011 Sep;68(3):593-601
pubmed: 21116625
Angew Chem Int Ed Engl. 2011 Jan 17;50(3):586-621
pubmed: 21226137
J Agric Food Chem. 2011 Mar 23;59(6):2725-33
pubmed: 21355597
J Surg Res. 2013 Apr;180(2):208-15
pubmed: 22572619
Reprod Toxicol. 2012 Nov;34(3):340-6
pubmed: 22687363
Biol Reprod. 2012 Oct 25;87(4):100
pubmed: 22811576
Biol Reprod. 2012 Dec 27;87(6):154
pubmed: 23136300
J Pineal Res. 2013 Oct;55(3):267-74
pubmed: 23772689
Fertil Steril. 2014 Feb;101(2):577-86
pubmed: 24314921
Br J Pharmacol. 2014 Apr;171(7):1747-57
pubmed: 24417315
Int J Mol Sci. 2014 Feb 25;15(3):3389-402
pubmed: 24573251
Pharmacol Rep. 2015 Dec;67(6):1264-72
pubmed: 26481551
Chem Res Toxicol. 2016 Jan 19;29(1):47-57
pubmed: 26700463
Eur J Pharmacol. 2016 Apr 15;777:9-16
pubmed: 26921755
J Pediatr Surg. 2016 Jul;51(7):1192-6
pubmed: 26976774
Brain Res. 2016 Jul 15;1643:70-9
pubmed: 27107941
Theriogenology. 2017 Feb;89:47-57
pubmed: 28043370
J Nutr Biochem. 2017 Jun;44:11-21
pubmed: 28343084
Anim Sci J. 2017 Sep;88(9):1298-1310
pubmed: 28349625
Oncotarget. 2017 Jun 27;8(26):41988-42000
pubmed: 28410217
Cardiovasc Drugs Ther. 2018 Apr;32(2):147-163
pubmed: 29556862
Biol Trace Elem Res. 1995 Jan-Mar;47(1-3):327-31
pubmed: 7779566
Atherosclerosis. 1997 Nov;135(1):93-102
pubmed: 9395277
Hum Reprod. 1998 Apr;13(4):998-1002
pubmed: 9619561