A randomized double blinded study to determine the effectiveness of utilizing intraperitoneal bupivacaine: Does it reduce postoperative opioid use following laparoscopic appendectomy?
Intraperitoneal local anesthetic
Laparoscopic appendectomy
Postoperative narcotic use
Postoperative opioid use
Postoperative pain
Journal
American journal of surgery
ISSN: 1879-1883
Titre abrégé: Am J Surg
Pays: United States
ID NLM: 0370473
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
received:
21
07
2018
revised:
28
10
2018
accepted:
30
10
2018
pubmed:
18
11
2018
medline:
21
11
2019
entrez:
18
11
2018
Statut:
ppublish
Résumé
Improving postoperative pain control may lead to improved outcomes including decreased opioid use, shorter hospital stays, and improved patient satisfaction. This study examined the effects of instilling intraperitoneal bupivacaine following laparoscopic appendectomy. In this prospective, randomized, double-blinded, placebo-controlled study, patients with appendicitis were randomized to receive either the bupivacaine or normal saline instilled at the appendectomy site prior to close. Postoperative pain scores, opioid doses and length of stay were recorded. Pain scores were lower (mean 2.48 versus 3.8; p = 0.014), and postoperative opioid use was lower (mean 7.394 mg versus 16.921 mg; p = 0.007) in the bupivacaine group. Instilling bupivacaine at the base of the cecum at the conclusion of laparoscopic appendectomy was associated with reducing postoperative pain scores and in hospital opioid use. This prospective, randomized, double-blinded, placebo-controlled study enrolled subjects with acute appendicitis undergoing laparoscopic appendectomy. Subjects were randomized to receive either bupivacaine or normal saline intraperitoneally at the close of surgery. In the bupivacaine group, pain scores at 1 h were improved and inpatient postoperative opioid use was less.
Sections du résumé
BACKGROUND
Improving postoperative pain control may lead to improved outcomes including decreased opioid use, shorter hospital stays, and improved patient satisfaction. This study examined the effects of instilling intraperitoneal bupivacaine following laparoscopic appendectomy.
METHODS
In this prospective, randomized, double-blinded, placebo-controlled study, patients with appendicitis were randomized to receive either the bupivacaine or normal saline instilled at the appendectomy site prior to close. Postoperative pain scores, opioid doses and length of stay were recorded.
RESULTS
Pain scores were lower (mean 2.48 versus 3.8; p = 0.014), and postoperative opioid use was lower (mean 7.394 mg versus 16.921 mg; p = 0.007) in the bupivacaine group.
CONCLUSIONS
Instilling bupivacaine at the base of the cecum at the conclusion of laparoscopic appendectomy was associated with reducing postoperative pain scores and in hospital opioid use.
STATEMENT
This prospective, randomized, double-blinded, placebo-controlled study enrolled subjects with acute appendicitis undergoing laparoscopic appendectomy. Subjects were randomized to receive either bupivacaine or normal saline intraperitoneally at the close of surgery. In the bupivacaine group, pain scores at 1 h were improved and inpatient postoperative opioid use was less.
Identifiants
pubmed: 30446161
pii: S0002-9610(18)31011-0
doi: 10.1016/j.amjsurg.2018.10.045
pii:
doi:
Substances chimiques
Analgesics, Opioid
0
Anesthetics, Local
0
Bupivacaine
Y8335394RO
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
479-482Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.