Integrating anatomo-physiological changes and pharmacogenomics in anti-infective therapy management: is it a major concern?
Administration, Oral
Adult
Anorexia Nervosa
/ complications
Antifungal Agents
/ administration & dosage
Azoles
/ administration & dosage
Cytochrome P-450 CYP2C19
/ genetics
Female
Humans
Intestinal Absorption
/ physiology
Pharmacogenomic Testing
Polymorphism, Single Nucleotide
Pulmonary Aspergillosis
/ complications
Treatment Outcome
cytochrome P450 enzymes
drug metabolism
genetic polymorphism
pharmacogenomics
therapeutic drug monitoring
Journal
British journal of clinical pharmacology
ISSN: 1365-2125
Titre abrégé: Br J Clin Pharmacol
Pays: England
ID NLM: 7503323
Informations de publication
Date de publication:
01 2019
01 2019
Historique:
received:
11
06
2018
revised:
17
09
2018
accepted:
30
09
2018
pubmed:
18
11
2018
medline:
31
12
2019
entrez:
18
11
2018
Statut:
ppublish
Résumé
Success of anti-infective therapy is a major challenge in some patients given anatomo-physiological changes and genetic variations. In this case anecdote, we report the management strategy of a patient suffering from chronic pulmonary aspergillosis in a context of anorexia nervosa and genetic polymorphism.
Identifiants
pubmed: 30447013
doi: 10.1111/bcp.13785
pmc: PMC6303195
doi:
Substances chimiques
Antifungal Agents
0
Azoles
0
CYP2C19 protein, human
EC 1.14.14.1
Cytochrome P-450 CYP2C19
EC 1.14.14.1
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
263-265Informations de copyright
© 2018 The British Pharmacological Society.
Références
Br J Clin Pharmacol. 2019 Jan;85(1):263-265
pubmed: 30447013
Int J Eat Disord. 2014 Mar;47(2):203-5
pubmed: 24488839
Mol Psychiatry. 2004 Jan;9(1):76-80
pubmed: 14699443
Pharmacogenomics J. 2016 Apr;16(2):113-23
pubmed: 26503820
Clin Pharmacol Ther. 2018 Feb;103(2):187
pubmed: 28786218
Curr Fungal Infect Rep. 2015 Jun;9(2):74-87
pubmed: 26918067
Pharmacogenomics. 2017 Aug;18(12):1119-1123
pubmed: 28745547
AAPS J. 2013 Oct;15(4):1242-52
pubmed: 24027036
AAPS J. 2013 Apr;15(2):415-26
pubmed: 23319287
J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Mar 1;919-920:1-9
pubmed: 23384531
Br J Clin Pharmacol. 2009 Dec;68(6):906-15
pubmed: 20002085
Antimicrob Agents Chemother. 2013 Apr;57(4):1888-94
pubmed: 23380734
Clin Pharmacol Ther. 2017 Jul;102(1):45-51
pubmed: 27981572