Prolonged QRS duration as a predictor of right ventricular dysfunction after balloon pulmonary angioplasty.
Balloon pulmonary angioplasty
Chronic thromboembolic pulmonary hypertension
Electrocardiography
Right ventricular dysfunction
Sex difference
Journal
International journal of cardiology
ISSN: 1874-1754
Titre abrégé: Int J Cardiol
Pays: Netherlands
ID NLM: 8200291
Informations de publication
Date de publication:
01 04 2019
01 04 2019
Historique:
received:
21
05
2018
revised:
23
10
2018
accepted:
08
11
2018
pubmed:
19
11
2018
medline:
18
12
2019
entrez:
19
11
2018
Statut:
ppublish
Résumé
Balloon pulmonary angioplasty (BPA) has shown beneficial effects for chronic thromboembolic pulmonary hypertension (CTEPH). However, previous studies have shown less cardiac output improvement and symptoms remaining after BPA, implying poor right ventricular (RV) function recovery. Therefore, we investigated the residual RV dysfunction after BPA to reveal risk factors, clinical effects, and possible underlying histopathological mechanisms. We investigated 61 consecutive CTEPH patients who underwent cardiovascular magnetic resonance before and 3 and 12 months after BPA series. Residual dysfunction (RD) of RV was defined as RV end-diastolic volume index >100 ml/m Relatively high percentage (44%) of residual RV dysfunction with worse WHO functional class was observed in CTEPH patients even after BPA. Prolonged QRS duration may predict poor recovery in RV function after BPA.
Sections du résumé
BACKGROUND
Balloon pulmonary angioplasty (BPA) has shown beneficial effects for chronic thromboembolic pulmonary hypertension (CTEPH). However, previous studies have shown less cardiac output improvement and symptoms remaining after BPA, implying poor right ventricular (RV) function recovery. Therefore, we investigated the residual RV dysfunction after BPA to reveal risk factors, clinical effects, and possible underlying histopathological mechanisms.
METHODS AND RESULTS
We investigated 61 consecutive CTEPH patients who underwent cardiovascular magnetic resonance before and 3 and 12 months after BPA series. Residual dysfunction (RD) of RV was defined as RV end-diastolic volume index >100 ml/m
CONCLUSIONS
Relatively high percentage (44%) of residual RV dysfunction with worse WHO functional class was observed in CTEPH patients even after BPA. Prolonged QRS duration may predict poor recovery in RV function after BPA.
Identifiants
pubmed: 30448112
pii: S0167-5273(18)33068-7
doi: 10.1016/j.ijcard.2018.11.026
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
176-181Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2018 Elsevier B.V. All rights reserved.