Autoimmune Encephalitis as an Extra-articular Manifestation of Rheumatoid Arthritis.


Journal

Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241

Informations de publication

Date de publication:
01 Apr 2019
Historique:
pubmed: 20 11 2018
medline: 22 5 2019
entrez: 20 11 2018
Statut: ppublish

Résumé

Autoimmune encephalitis (AE) is an immune-mediated encephalitis characterized by the subacute onset of memory deficits, altered mental status, or psychiatric symptoms. Limbic encephalitis associated with rheumatoid arthritis (RA) has not been reported yet. A 57-year-old man presented with the subacute onset of headache, depression, and anorexia 7 months before the onset of RA. Brain magnetic resonance imaging showed symmetric parenchymal lesions involving the medial temporal lobes. He was diagnosed with RA and AE, but no autoantibodies to neuronal intracellular or cell-surface antigens were identified in either the serum or cerebrospinal fluid. His symptoms improved with immunotherapy. AE can develop as an extra-articular manifestation of RA.

Identifiants

pubmed: 30449780
doi: 10.2169/internalmedicine.1846-18
pmc: PMC6478993
doi:

Substances chimiques

Autoantibodies 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1007-1009

Références

Clin Rheumatol. 2003 Dec;22(6):475-80
pubmed: 14677033
Neurology. 2007 Mar 27;68(13):1079-80
pubmed: 17389318
Neurol Sci. 2011 Dec;32(6):1191-4
pubmed: 21863270
Neurologia. 2013 Jan-Feb;28(1):63-4
pubmed: 21907463
Autoimmun Rev. 2011 Dec;11(2):123-31
pubmed: 21939785
Joint Bone Spine. 2012 Jul;79(4):351-5
pubmed: 22281228
Neurol Sci. 2015 Jun;36(6):1047-8
pubmed: 25596712
Lancet Neurol. 2016 Apr;15(4):391-404
pubmed: 26906964
Case Rep Neurol. 2016 Jul 20;8(2):156-160
pubmed: 27721779

Auteurs

Eiji Kitamura (E)

Department of Neurology, Kitasato University School of Medicine, Japan.

Yuko Kondo (Y)

Department of Neurology, Kitasato University School of Medicine, Japan.

Naomi Kanazawa (N)

Department of Neurology, Kitasato University School of Medicine, Japan.

Tsugio Akutsu (T)

Department of Neurology, Kitasato University School of Medicine, Japan.

Kazutoshi Nishiyama (K)

Department of Neurology, Kitasato University School of Medicine, Japan.

Takahiro Iizuka (T)

Department of Neurology, Kitasato University School of Medicine, Japan.

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Classifications MeSH