Klebsiella pneumoniae infection biology: living to counteract host defences.
Klebsiella
innate immunity
virulence
Journal
FEMS microbiology reviews
ISSN: 1574-6976
Titre abrégé: FEMS Microbiol Rev
Pays: England
ID NLM: 8902526
Informations de publication
Date de publication:
01 03 2019
01 03 2019
Historique:
received:
10
09
2018
accepted:
16
11
2018
pubmed:
20
11
2018
medline:
27
4
2019
entrez:
20
11
2018
Statut:
ppublish
Résumé
Klebsiella species cause a wide range of diseases including pneumonia, urinary tract infections (UTIs), bloodstream infections and sepsis. These infections are particularly a problem among neonates, elderly and immunocompromised individuals. Klebsiella is also responsible for a significant number of community-acquired infections. A defining feature of these infections is their morbidity and mortality, and the Klebsiella strains associated with them are considered hypervirulent. The increasing isolation of multidrug-resistant strains has significantly narrowed, or in some settings completely removed, the therapeutic options for the treatment of Klebsiella infections. Not surprisingly, this pathogen has then been singled out as an 'urgent threat to human health' by several organisations. This review summarises the tremendous progress that has been made to uncover the sophisticated immune evasion strategies of K. pneumoniae. The co-evolution of Klebsiella in response to the challenge of an activated immune has made Klebsiella a formidable pathogen exploiting stealth strategies and actively suppressing innate immune defences to overcome host responses to survive in the tissues. A better understanding of Klebsiella immune evasion strategies in the context of the host-pathogen interactions is pivotal to develop new therapeutics, which can be based on antagonising the anti-immune strategies of this pathogen.
Identifiants
pubmed: 30452654
pii: 5188677
doi: 10.1093/femsre/fuy043
pmc: PMC6435446
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
123-144Subventions
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/P006078/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/P020194/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/R005893/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/L007223/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/N00700X/1
Pays : United Kingdom
Informations de copyright
© FEMS 2018.
Références
Antimicrob Agents Chemother. 2014 Dec;58(12):7375-82
pubmed: 25267669
Trends Cell Biol. 2018 Feb;28(2):143-156
pubmed: 29173800
Medicine (Baltimore). 2014 Oct;93(17):298-309
pubmed: 25398065
Insect Sci. 2017 Jun;24(3):342-357
pubmed: 26847724
Clin Infect Dis. 2005 Aug 1;41 Suppl 3:S213-7
pubmed: 15983903
J Biol Chem. 2015 Jul 3;290(27):16678-97
pubmed: 25971969
Am J Respir Cell Mol Biol. 2001 Sep;25(3):335-40
pubmed: 11588011
J Interferon Cytokine Res. 2005 Feb;25(2):103-12
pubmed: 15695931
Immunity. 2014 Oct 16;41(4):518-28
pubmed: 25367569
Cell Host Microbe. 2016 Jun 8;19(6):760-9
pubmed: 27281568
Infect Immun. 2002 Mar;70(3):1075-80
pubmed: 11854185
Infect Immun. 1994 Oct;62(10):4495-9
pubmed: 7927714
Immunity. 2016 Feb 16;44(2):368-79
pubmed: 26885859
Nat Immunol. 2010 Dec;11(12):1136-42
pubmed: 21057511
Antimicrob Agents Chemother. 2016 Sep 23;60(10):6115-20
pubmed: 27480857
N Engl J Med. 2014 Mar 27;370(13):1198-208
pubmed: 24670166
Nature. 2011 Sep 14;477(7366):596-600
pubmed: 21918512
Infect Immun. 2009 Feb;77(2):714-24
pubmed: 19015258
Microbiology. 1999 Mar;145 ( Pt 3):673-679
pubmed: 10217501
Cell Microbiol. 2006 Jan;8(1):139-48
pubmed: 16367873
Infect Immun. 2016 Jan 04;84(3):782-9
pubmed: 26729763
PLoS One. 2017 Jan 12;12(1):e0170125
pubmed: 28081233
Subcell Biochem. 2010;53:241-53
pubmed: 20593270
Res Microbiol. 2018 Sep - Oct;169(7-8):425-431
pubmed: 29128373
Nat Immunol. 2002 Apr;3(4):354-9
pubmed: 11912497
Antimicrob Agents Chemother. 2014 Oct;58(10):5696-703
pubmed: 25022583
Immunol Rev. 2016 Nov;274(1):33-58
pubmed: 27782325
Microbiology. 2008 Dec;154(Pt 12):3877-3886
pubmed: 19047754
J Biol Chem. 2011 Jun 17;286(24):21041-51
pubmed: 21478151
Nature. 2007 Nov 29;450(7170):725-30
pubmed: 18046412
Int J Antimicrob Agents. 2011 Jul;38(1):39-45
pubmed: 21514798
Nat Med. 2015 Feb;21(2):119-20
pubmed: 25654602
Am J Physiol. 1997 Feb;272(2 Pt 1):L344-52
pubmed: 9124386
Antimicrob Agents Chemother. 2009 Jan;53(1):298-302
pubmed: 19015361
Infect Immun. 1998 Jun;66(6):2822-6
pubmed: 9596755
PLoS Pathog. 2018 Oct 1;14(10):e1007338
pubmed: 30273394
Nat Med. 2016 Aug;22(8):952-60
pubmed: 27376574
J Immunol. 2010 Nov 15;185(10):6214-25
pubmed: 20937845
Infect Immun. 2004 Dec;72(12):7107-14
pubmed: 15557634
Adv Exp Med Biol. 2012;710:11-7
pubmed: 22127881
Antimicrob Agents Chemother. 2017 Mar 24;61(4):
pubmed: 28115349
J Med Microbiol. 2012 Feb;61(Pt 2):239-45
pubmed: 21940650
Nat Rev Immunol. 2016 Sep;16(9):566-80
pubmed: 27455396
Am J Physiol Lung Cell Mol Physiol. 2008 Mar;294(3):L387-98
pubmed: 18162603
Cell. 2010 Mar 19;140(6):805-20
pubmed: 20303872
J Immunol. 2014 Feb 15;192(4):1778-86
pubmed: 24442439
Cell Microbiol. 2007 Aug;9(8):1871-9
pubmed: 17490408
J Infect Dis. 2016 May 15;213(10):1615-22
pubmed: 26768252
Science. 2010 May 21;328(5981):1040-3
pubmed: 20395475
Lancet Infect Dis. 2006 Sep;6(9):589-601
pubmed: 16931410
J Immunol. 2015 Dec 1;195(11):5169-77
pubmed: 26525287
Sci Rep. 2017 Oct 19;7(1):13533
pubmed: 29051525
Nature. 2000 Dec 7;408(6813):740-5
pubmed: 11130078
Lancet Infect Dis. 2016 Apr;16(4):e47-63
pubmed: 27036359
Mol Immunol. 2005 Feb;42(3):279-87
pubmed: 15589315
Antimicrob Agents Chemother. 2006 Jul;50(7):2361-7
pubmed: 16801413
Nature. 2014 Oct 9;514(7521):187-92
pubmed: 25119034
Nat Rev Immunol. 2007 May;7(5):353-64
pubmed: 17457343
J Biol Chem. 2000 Oct 20;275(42):32940-9
pubmed: 10903325
mBio. 2018 Apr 3;9(2):
pubmed: 29615497
PLoS Genet. 2009 Dec;5(12):e1000788
pubmed: 20041203
Lancet Infect Dis. 2012 Nov;12(11):881-7
pubmed: 23099082
PLoS One. 2010 Mar 26;5(3):e9896
pubmed: 20360853
Nat Med. 2008 Mar;14(3):275-81
pubmed: 18264110
PLoS One. 2014 Sep 09;9(9):e107394
pubmed: 25203254
Nat Commun. 2017 Nov 15;8(1):1512
pubmed: 29142211
Microbiology. 2006 Feb;152(Pt 2):555-66
pubmed: 16436443
Appl Environ Microbiol. 2001 Jul;67(7):3325-7
pubmed: 11425763
JCI Insight. 2016 Oct 20;1(17):e89704
pubmed: 27777978
FEMS Microbiol Rev. 2017 May 1;41(3):252-275
pubmed: 28521338
Antimicrob Agents Chemother. 2015 May;59(5):2898-900
pubmed: 25691629
Infect Immun. 2011 Mar;79(3):997-1006
pubmed: 21173313
Front Microbiol. 2017 Mar 01;8:276
pubmed: 28298903
PLoS One. 2016 Jan 26;11(1):e0146365
pubmed: 26812644
Nat Rev Immunol. 2014 Mar;14(3):166-80
pubmed: 24481336
J Innate Immun. 2009;1(2):136-44
pubmed: 20375572
Immunity. 2013 May 23;38(5):870-80
pubmed: 23706668
Am J Pathol. 2015 Feb;185(2):420-31
pubmed: 25485859
Infect Immun. 1996 Dec;64(12):5211-8
pubmed: 8945568
Nature. 2015 Jan 15;517(7534):311-20
pubmed: 25592536
Infect Immun. 2018 Jun 21;86(7):
pubmed: 29712730
Infect Immun. 2001 Jan;69(1):24-33
pubmed: 11119485
PLoS Pathog. 2014 Sep 25;10(9):e1004368
pubmed: 25254554
J Med Microbiol. 2000 Nov;49(11):1003-1010
pubmed: 11073154
Curr Issues Mol Biol. 2006 Jan;8(1):11-26
pubmed: 16450883
Clin Vaccine Immunol. 2017 Jan 5;24(1):
pubmed: 27795303
Antimicrob Agents Chemother. 2016 Oct 21;60(11):6837-6843
pubmed: 27600049
J Exp Med. 2005 Sep 19;202(6):761-9
pubmed: 16157683
J Immunol. 2012 Jun 1;188(11):5623-35
pubmed: 22547706
Annu Rev Immunol. 2003;21:547-78
pubmed: 12524383
Cell Microbiol. 2014 Mar;16(3):311-23
pubmed: 24128258
Antimicrob Agents Chemother. 2010 Jan;54(1):177-83
pubmed: 19858254
J Biol Chem. 2007 May 25;282(21):15569-77
pubmed: 17371870
Infect Immun. 1993 Mar;61(3):852-60
pubmed: 8432605
J Immunol. 2004 Oct 15;173(8):5148-55
pubmed: 15470059
Front Microbiol. 2017 Apr 12;8:614
pubmed: 28446900
J Med Microbiol. 2001 May;50(5):456-461
pubmed: 11339254
PLoS Pathog. 2017 Nov 7;13(11):e1006696
pubmed: 29112952
Immunol Res. 1999;20(1):15-27
pubmed: 10467980
Curr Top Microbiol Immunol. 2014;380:157-90
pubmed: 25004818
Cell Microbiol. 2015 Nov;17(11):1537-60
pubmed: 26045209
J Leukoc Biol. 2005 Aug;78(2):544-54
pubmed: 15894582
J Antimicrob Chemother. 2010 May;65(5):986-90
pubmed: 20211860
J Med Microbiol. 2013 Dec;62(Pt 12):1790-1798
pubmed: 24000226
Shock. 2014 Apr;41(4):301-10
pubmed: 24430542
Infect Immun. 2002 Nov;70(11):6310-8
pubmed: 12379710
Proc Natl Acad Sci U S A. 2012 May 22;109(21):E1360-8
pubmed: 22538807
Infect Immun. 2004 Mar;72(3):1767-74
pubmed: 14977986
Clin Infect Dis. 2017 Jul 15;65(2):208-215
pubmed: 28369261
Antimicrob Agents Chemother. 2011 Apr;55(4):1485-93
pubmed: 21282452
J Immunol. 2009 Nov 15;183(10):6629-38
pubmed: 19846873
Clin Microbiol Rev. 1998 Oct;11(4):589-603
pubmed: 9767057
Int J Antimicrob Agents. 2015 Jun;45(6):635-40
pubmed: 25681067
J Exp Med. 2016 Sep 19;213(10):2113-28
pubmed: 27573815
J Immunol. 2009 Apr 15;182(8):4947-56
pubmed: 19342674
Trends Immunol. 2002 Aug;23(8):375-8
pubmed: 12133792
Cell. 2016 Apr 21;165(3):679-89
pubmed: 27040495
J Immunol. 1996 Dec 15;157(12):5221-4
pubmed: 8955165
Microb Genom. 2018 Sep;4(9):
pubmed: 29985125
Front Cell Infect Microbiol. 2018 Jan 22;8:4
pubmed: 29404282
mBio. 2012 Nov 20;3(6):
pubmed: 23169997
Cell Microbiol. 2006 Sep;8(9):1467-74
pubmed: 16922865
Infect Immun. 2011 Aug;79(8):3309-16
pubmed: 21576334
Front Immunol. 2016 Dec 26;7:652
pubmed: 28082986
EMBO Mol Med. 2013 Apr;5(4):516-30
pubmed: 23554169
Infect Immun. 2015 Sep;83(9):3418-27
pubmed: 26056382
J Immunol. 2009 Aug 1;183(3):2008-15
pubmed: 19587006
Infect Immun. 2009 Jul;77(7):2657-71
pubmed: 19433545
Biochemistry. 2008 Mar 4;47(9):2814-25
pubmed: 18254598
Antimicrob Agents Chemother. 1999 Jul;43(7):1669-73
pubmed: 10390220
Respir Res. 2013 Sep 17;14:91
pubmed: 24044871
J Immunol. 2000 Sep 1;165(5):2643-50
pubmed: 10946293
J Infect Dis. 2007 Jul 1;196(1):95-103
pubmed: 17538889
Clin Microbiol Infect. 2013 Jan;19(1):E23-E30
pubmed: 23137235
Trends Microbiol. 2017 Nov;25(11):906-918
pubmed: 28625530
Infect Immun. 1992 Jun;60(6):2529-35
pubmed: 1587619
Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3574-81
pubmed: 26100894
J Biol Chem. 2011 Mar 25;286(12):9956-67
pubmed: 21278256
Nat Rev Microbiol. 2005 Apr;3(4):281-94
pubmed: 15806094
mBio. 2016 Sep 13;7(5):
pubmed: 27624128
Invest Ophthalmol Vis Sci. 2004 Aug;45(8):2569-76
pubmed: 15277479
Infect Immun. 2001 Oct;69(10):6364-9
pubmed: 11553580
PLoS One. 2013;8(2):e56847
pubmed: 23457627
Infect Immun. 2005 Dec;73(12):8226-36
pubmed: 16299319
Microbiol Mol Biol Rev. 2003 Dec;67(4):593-656
pubmed: 14665678
Virulence. 2016 Apr 2;7(3):214-29
pubmed: 26730990
J Immunol. 2000 Sep 1;165(5):2335-40
pubmed: 10946255
Lancet Infect Dis. 2018 Jan;18(1):25
pubmed: 29102518
Infect Immun. 2010 Mar;78(3):1135-46
pubmed: 20008534
Infect Immun. 2007 Oct;75(10):4942-50
pubmed: 17646358
Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):E6369-78
pubmed: 26578797
J Immunol. 1998 Sep 1;161(5):2435-40
pubmed: 9725241
Infect Immun. 2006 Sep;74(9):5402-7
pubmed: 16926436
J Infect Dis. 1996 Jan;173(1):159-65
pubmed: 8537653
Eur J Immunol. 2016 Jul;46(7):1592-9
pubmed: 27139187
Infect Immun. 1998 Nov;66(11):5140-6
pubmed: 9784515
Clin Microbiol Infect. 2016 May;22(5):444-50
pubmed: 26850826
Front Immunol. 2018 Jan 04;8:1906
pubmed: 29354124
Infect Immun. 2010 Jan;78(1):210-9
pubmed: 19841082
Curr Top Microbiol Immunol. 2006;306:27-66
pubmed: 16909917
Cell. 2014 Dec 4;159(6):1312-26
pubmed: 25480296
Nat Immunol. 2015 Jan;16(1):27-35
pubmed: 25521682
J Infect Dis. 2016 Dec 1;214(11):1752-1761
pubmed: 27651419
Virulence. 2013 Oct 1;4(7):597-603
pubmed: 23921374
Immunity. 2014 Jul 17;41(1):14-20
pubmed: 25035950
Infect Immun. 2014 Jun;82(6):2356-67
pubmed: 24664504
PLoS One. 2011;6(10):e26734
pubmed: 22039542
Nat Med. 2015 Jul;21(7):677-87
pubmed: 26121197
PLoS Pathog. 2015 Jan 29;11(1):e1004627
pubmed: 25633080
Infect Immun. 1997 May;65(5):1870-5
pubmed: 9125574
J Immunol. 2004 Sep 15;173(6):4075-83
pubmed: 15356157
J Immunol. 2003 Dec 15;171(12):6697-705
pubmed: 14662873
J Antimicrob Chemother. 2015 Jan;70(1):81-8
pubmed: 25193085
Cell. 2011 Mar 4;144(5):675-88
pubmed: 21376231
J Clin Invest. 2002 Mar;109(6):707-12
pubmed: 11901176
Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7307-11
pubmed: 7638186
Cell Microbiol. 2011 Jan;13(1):135-53
pubmed: 20846183
Nat Immunol. 2000 Dec;1(6):502-9
pubmed: 11101872
Annu Rev Genet. 2016 Nov 23;50:67-91
pubmed: 27617971
J Exp Med. 1947 Aug 31;86(3):249-56
pubmed: 19871675
Emerg Infect Dis. 2002 Feb;8(2):160-6
pubmed: 11897067
J Immunol. 2001 Mar 1;166(5):3362-8
pubmed: 11207292
Am J Respir Cell Mol Biol. 2017 May;56(5):648-656
pubmed: 28187270
Toxicology. 2003 Jun 3;188(1):49-71
pubmed: 12748041
J Immunol. 2000 Jun 15;164(12):6166-73
pubmed: 10843666
Nat Rev Immunol. 2007 Mar;7(3):202-12
pubmed: 17318231
Sci Signal. 2016 Jan 05;9(409):ra3
pubmed: 26732763
Antimicrob Agents Chemother. 2013 Nov;57(11):5521-6
pubmed: 23979739
Infect Immun. 2014 Nov;82(11):4596-606
pubmed: 25135683
J Infect. 2015 Nov;71(5):553-60
pubmed: 26304687
Infect Immun. 2013 Oct;81(10):3552-65
pubmed: 23836821
Infect Immun. 2003 Mar;71(3):1306-15
pubmed: 12595446
mSphere. 2016 Oct 19;1(5):
pubmed: 27777984
Annu Rev Immunol. 2012;30:459-89
pubmed: 22224774
Eur J Immunol. 2010 Nov;40(11):3138-49
pubmed: 20865789
J Antimicrob Chemother. 2000 Aug;46(2):273-7
pubmed: 10933652
Infect Immun. 2004 Feb;72(2):788-94
pubmed: 14742522
J Infect Dis. 2012 Nov;206(9):1415-23
pubmed: 22904341
Infect Immun. 2017 Aug 18;85(9):
pubmed: 28652313
Front Immunol. 2012 Jan 31;3:4
pubmed: 22566890
J Antimicrob Chemother. 2009 Apr;63(4):659-67
pubmed: 19233898
Lancet Infect Dis. 2018 Jan;18(1):37-46
pubmed: 28864030
Am J Physiol Lung Cell Mol Physiol. 2012 Mar 1;302(5):L447-54
pubmed: 22160309
Nat Rev Immunol. 2013 Jun;13(6):397-411
pubmed: 23702978
EMBO Mol Med. 2017 Apr;9(4):430-447
pubmed: 28202493
Am J Respir Crit Care Med. 2014 Oct 1;190(7):722-32
pubmed: 25033332
J Immunol. 2003 May 1;170(9):4432-6
pubmed: 12707317
J Immunol. 2012 Feb 1;188(3):1411-20
pubmed: 22210917
Infect Immun. 2007 Mar;75(3):1463-72
pubmed: 17220312
Infect Immun. 2005 Dec;73(12):8282-90
pubmed: 16299325
J Immunol. 2006 Jul 1;177(1):538-47
pubmed: 16785551
Infect Immun. 2015 Sep;83(9):3396-409
pubmed: 26077758
FEMS Microbiol Rev. 1993 Nov;12(4):325-48
pubmed: 8268005
Clin Microbiol Rev. 2015 Apr;28(2):337-418
pubmed: 25788514
J Immunol. 2008 Sep 15;181(6):3733-9
pubmed: 18768823
J Immunol. 1995 Jul 15;155(2):722-9
pubmed: 7608550
Cell Microbiol. 2013 Jul;15(7):1212-33
pubmed: 23347154
Alcohol Clin Exp Res. 2006 Jul;30(7):1200-7
pubmed: 16792568
Front Cell Infect Microbiol. 2018 Feb 09;8:30
pubmed: 29479519
Immunol Rev. 2018 Jan;281(1):115-123
pubmed: 29247997
J Exp Med. 2001 Aug 20;194(4):519-27
pubmed: 11514607
BMC Microbiol. 2009 Aug 03;9:156
pubmed: 19650888
Infection. 1995 Nov-Dec;23(6):371-7
pubmed: 8655209
Science. 2013 Sep 13;341(6151):1250-3
pubmed: 24031018
FEMS Microbiol Rev. 2018 Jul 1;42(4):425-447
pubmed: 29596635
Mol Med. 2016 Sep;22:292-299
pubmed: 27508882
Microbiol Mol Biol Rev. 2016 Jun 15;80(3):629-61
pubmed: 27307579
PLoS One. 2017 Jun 6;12(6):e0178847
pubmed: 28586386
Infect Immun. 1996 Nov;64(11):4719-25
pubmed: 8890231
J Med Microbiol. 2001 Nov;50(11):959-964
pubmed: 11699592
PLoS Pathog. 2009 Oct;5(10):e1000622
pubmed: 19834550
Immunology. 2015 Apr;144(4):541-8
pubmed: 25684236
J Clin Microbiol. 2006 Aug;44(8):2831-7
pubmed: 16891499
J Immunol. 2007 Sep 15;179(6):3937-46
pubmed: 17785831
J Immunol. 1996 May 15;156(10):3583-6
pubmed: 8621890
Cell Host Microbe. 2016 Nov 9;20(5):596-605
pubmed: 27923703
Annu Rev Immunol. 2014;32:433-59
pubmed: 24499275
Nature. 2011 Sep 25;478(7370):515-8
pubmed: 21947006
Nat Immunol. 2014 Nov;15(11):1017-25
pubmed: 25217981
Infect Immun. 1997 Apr;65(4):1139-46
pubmed: 9119443
Nat Rev Immunol. 2008 Jul;8(7):501-11
pubmed: 18535581
Nat Immunol. 2006 Oct;7(10):1066-73
pubmed: 16980981
Infect Immun. 1996 Nov;64(11):4726-32
pubmed: 8890232
Infect Immun. 1992 Aug;60(8):3446-7
pubmed: 1639513
J Interferon Cytokine Res. 2010 Sep;30(9):643-52
pubmed: 20726789
Nat Immunol. 2010 Sep;11(9):785-97
pubmed: 20720586
Nat Microbiol. 2016 Dec 19;2:16246
pubmed: 27991883
Eur Respir J. 2011 Apr;37(4):848-57
pubmed: 20650991
Nat Commun. 2018 Jul 13;9(1):2703
pubmed: 30006589
Nat Rev Immunol. 2003 Sep;3(9):710-20
pubmed: 12949495
Antimicrob Agents Chemother. 1998 Jul;42(7):1636-40
pubmed: 9660996
Infect Immun. 2011 Sep;79(9):3718-32
pubmed: 21708987
J Cell Sci. 2014 Jun 1;127(Pt 11):2383-90
pubmed: 24829146
Pathog Dis. 2015 Jul;73(5):
pubmed: 25819035
Infect Immun. 2000 Feb;68(2):953-5
pubmed: 10639470
Infect Immun. 2000 Dec;68(12):6744-9
pubmed: 11083790
J Innate Immun. 2015;7(6):637-46
pubmed: 26065469
Cell. 2015 Dec 3;163(6):1326-32
pubmed: 26638069
PLoS One. 2011;6(11):e28216
pubmed: 22132240
Nature. 2010 Mar 4;464(7285):104-7
pubmed: 20203610
J Immunol. 2002 Apr 15;168(8):4018-24
pubmed: 11937559
J Exp Med. 1947 Aug 31;86(3):239-48
pubmed: 19871674
Am J Respir Crit Care Med. 2006 Jan 1;173(1):122-9
pubmed: 16210672
Front Cell Infect Microbiol. 2017 Sep 06;7:393
pubmed: 28932706
Infect Immun. 2011 May;79(5):1998-2005
pubmed: 21343351