Lack of associations between thyroid function and obstructive sleep apnea severity in adults with prediabetes and diabetes mellitus.
Hypothyroidism
Polysomnography
Sleep apnea syndromes
Thyrotropin
Thyroxine
Triiodothyronine
Journal
Sleep & breathing = Schlaf & Atmung
ISSN: 1522-1709
Titre abrégé: Sleep Breath
Pays: Germany
ID NLM: 9804161
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
15
08
2018
accepted:
13
11
2018
revised:
18
10
2018
pubmed:
21
11
2018
medline:
3
11
2020
entrez:
21
11
2018
Statut:
ppublish
Résumé
Hypothyroidism is associated with a high frequency of obstructive sleep apnea (OSA). However, the prevalence of OSA in hypothyroid patients is not different from the general population in many reports. The importance of thyroid function screening in sleep-disordered breathing is still controversial. This study aimed to explore the association between thyroid dysfunction and OSA in the adults with prediabetes or diabetes mellitus type 2, who have very high prevalence of OSA. OSA was assessed using an in-home monitoring device, WatchPAT200. OSA severity was measured using apnea-hypopnea index (AHI), oxygen desaturation index (ODI), minimum oxygen saturation (minO2), and time spent under oxygen saturation < 90% (T90). Patients with pre-existing thyroid dysfunction were excluded. Participants included 70 men and 118 women with mean age 52.8 ± 10.9 years and body mass index 28.2 ± 4.9 kg/m These data do not support universal screening for thyroid dysfunction in OSA patients with diabetes or prediabetes.
Identifiants
pubmed: 30456738
doi: 10.1007/s11325-018-1756-x
pii: 10.1007/s11325-018-1756-x
doi:
Substances chimiques
Triiodothyronine
06LU7C9H1V
Thyrotropin
9002-71-5
Thyroxine
Q51BO43MG4
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
963-967Subventions
Organisme : The Endocrine Society of Thailand
ID : Not applicable
Organisme : Mahidol University
ID : Not applicable
Références
Taylor PN, Albrecht D, Scholz A, Gutierrez-Buey G, Lazarus JH, Dayan CM, Okosieme OE (2018) Global epidemiology of hyperthyroidism and hypothyroidism. Nat Rev Endocrinol 14(5):301–316. https://doi.org/10.1038/nrendo.2018.18
doi: 10.1038/nrendo.2018.18
pubmed: 29569622
Heinzer R, Vat S, Marques-Vidal P, Marti-Soler H, Andries D, Tobback N, Mooser V, Preisig M, Malhotra A, Waeber G, Vollenweider P, Tafti M, Haba-Rubio J (2015) Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study. Lancet Respir Med 3(4):310–318. https://doi.org/10.1016/S2213-2600(15)00043-0
doi: 10.1016/S2213-2600(15)00043-0
pubmed: 25682233
pmcid: 4404207
Jha A, Sharma SK, Tandon N, Lakshmy R, Kadhiravan T, Handa KK, Gupta R, Pandey RM, Chaturvedi PK (2006) Thyroxine replacement therapy reverses sleep-disordered breathing in patients with primary hypothyroidism. Sleep Med 7(1):55–61. https://doi.org/10.1016/j.sleep.2005.05.003
doi: 10.1016/j.sleep.2005.05.003
pubmed: 16198143
Winkelman JW, Goldman H, Piscatelli N, Lukas SE, Dorsey CM, Cunningham S (1996) Are thyroid function tests necessary in patients with suspected sleep apnea? Sleep 19(10):790–793
doi: 10.1093/sleep/19.10.790
Kapur VK, Koepsell TD, deMaine J, Hert R, Sandblom RE, Psaty BM (1998) Association of hypothyroidism and obstructive sleep apnea. Am J Respir Crit Care Med 158(5 Pt 1):1379–1383. https://doi.org/10.1164/ajrccm.158.5.9712069
doi: 10.1164/ajrccm.158.5.9712069
pubmed: 9817682
Miller CM, Husain AM (2003) Should women with obstructive sleep apnea syndrome be screened for hypothyroidism? Sleep Breath 7(4):185–188. https://doi.org/10.1007/s11325-003-0185-6
doi: 10.1007/s11325-003-0185-6
pubmed: 14710338
Resta O, Pannacciulli N, Di Gioia G, Stefano A, Barbaro MP, De Pergola G (2004) High prevalence of previously unknown subclinical hypothyroidism in obese patients referred to a sleep clinic for sleep disordered breathing. Nutr Metab Cardiovasc Dis 14(5):248–253
doi: 10.1016/S0939-4753(04)80051-6
Bahammam SA, Sharif MM, Jammah AA, Bahammam AS (2011) Prevalence of thyroid disease in patients with obstructive sleep apnea. Respir Med 105(11):1755–1760. https://doi.org/10.1016/j.rmed.2011.07.007
doi: 10.1016/j.rmed.2011.07.007
pubmed: 21820299
Reutrakul S, Mokhlesi B (2017) Obstructive sleep apnea and diabetes: a state of the art review. Chest 152(5):1070–1086. https://doi.org/10.1016/j.chest.2017.05.009
doi: 10.1016/j.chest.2017.05.009
pubmed: 28527878
pmcid: 5812754
Sriphrapradang C, Pavarangkoon S, Jongjaroenprasert W, Chailurkit LO, Ongphiphadhanakul B, Aekplakorn W (2014) Reference ranges of serum TSH, FT4 and thyroid autoantibodies in the Thai population: the national health examination survey. Clin Endocrinol 80(5):751–756. https://doi.org/10.1111/cen.12371
doi: 10.1111/cen.12371
Mete T, Yalcin Y, Berker D, Ciftci B, Guven Firat S, Topaloglu O, Cinar Yavuz H, Guler S (2013) Relationship between obstructive sleep apnea syndrome and thyroid diseases. Endocrine 44(3):723–728. https://doi.org/10.1007/s12020-013-9927-9
doi: 10.1007/s12020-013-9927-9
pubmed: 23564558
Ozcan KM, Selcuk A, Ozcan I, Ozdas T, Ozdogan F, Acar M, Dere H (2014) Incidence of hypothyroidism and its correlation with polysomnography findings in obstructive sleep apnea. Eur Arch Otorhinolaryngol 271(11):2937–2941. https://doi.org/10.1007/s00405-014-2962-1
doi: 10.1007/s00405-014-2962-1
pubmed: 24609648
Takeuchi S, Kitamura T, Ohbuchi T, Koizumi H, Takahashi R, Hohchi N, Suzuki H (2015) Relationship between sleep apnea and thyroid function. Sleep Breath 19(1):85–89. https://doi.org/10.1007/s11325-014-0966-0
doi: 10.1007/s11325-014-0966-0
pubmed: 24622960
Bozkurt NC, Karbek B, Cakal E, Firat H, Ozbek M, Delibasi T (2012) The association between severity of obstructive sleep apnea and prevalence of Hashimoto's thyroiditis. Endocr J 59(11):981–988
doi: 10.1507/endocrj.EJ12-0106
Sorensen JR, Winther KH, Bonnema SJ, Godballe C, Hegedus L (2016) Respiratory manifestations of hypothyroidism: a systematic review. Thyroid 26(11):1519–1527. https://doi.org/10.1089/thy.2015.0642
doi: 10.1089/thy.2015.0642
pubmed: 27673426
Mickelson SA, Lian T, Rosenthal L (1999) Thyroid testing and thyroid hormone replacement in patients with sleep disordered breathing. Ear Nose Throat J 78(10):768–771 774-765
doi: 10.1177/014556139907801009
Resta O, Carratu P, Carpagnano GE, Maniscalco M, Di Gioia G, Lacedonia D, Giorgino R, De Pergola G (2005) Influence of subclinical hypothyroidism and T4 treatment on the prevalence and severity of obstructive sleep apnoea syndrome (OSAS). J Endocrinol Investig 28(10):893–898
doi: 10.1007/BF03345320
Alexander EK, Pearce EN, Brent GA, Brown RS, Chen H, Dosiou C, Grobman WA, Laurberg P, Lazarus JH, Mandel SJ, Peeters RP, Sullivan S (2017) 2017 Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum. Thyroid 27(3):315–389. https://doi.org/10.1089/thy.2016.0457
doi: 10.1089/thy.2016.0457
pubmed: 28056690
Kadiyala R, Peter R, Okosieme OE (2010) Thyroid dysfunction in patients with diabetes: clinical implications and screening strategies. Int J Clin Pract 64(8):1130–1139. https://doi.org/10.1111/j.1742-1241.2010.02376.x
doi: 10.1111/j.1742-1241.2010.02376.x
pubmed: 20642711
Attal P, Chanson P (2010) Endocrine aspects of obstructive sleep apnea. J Clin Endocrinol Metab 95(2):483–495. https://doi.org/10.1210/jc.2009-1912
doi: 10.1210/jc.2009-1912
pubmed: 20061419