Lack of associations between thyroid function and obstructive sleep apnea severity in adults with prediabetes and diabetes mellitus.


Journal

Sleep & breathing = Schlaf & Atmung
ISSN: 1522-1709
Titre abrégé: Sleep Breath
Pays: Germany
ID NLM: 9804161

Informations de publication

Date de publication:
Sep 2019
Historique:
received: 15 08 2018
accepted: 13 11 2018
revised: 18 10 2018
pubmed: 21 11 2018
medline: 3 11 2020
entrez: 21 11 2018
Statut: ppublish

Résumé

Hypothyroidism is associated with a high frequency of obstructive sleep apnea (OSA). However, the prevalence of OSA in hypothyroid patients is not different from the general population in many reports. The importance of thyroid function screening in sleep-disordered breathing is still controversial. This study aimed to explore the association between thyroid dysfunction and OSA in the adults with prediabetes or diabetes mellitus type 2, who have very high prevalence of OSA. OSA was assessed using an in-home monitoring device, WatchPAT200. OSA severity was measured using apnea-hypopnea index (AHI), oxygen desaturation index (ODI), minimum oxygen saturation (minO2), and time spent under oxygen saturation < 90% (T90). Patients with pre-existing thyroid dysfunction were excluded. Participants included 70 men and 118 women with mean age 52.8 ± 10.9 years and body mass index 28.2 ± 4.9 kg/m These data do not support universal screening for thyroid dysfunction in OSA patients with diabetes or prediabetes.

Identifiants

pubmed: 30456738
doi: 10.1007/s11325-018-1756-x
pii: 10.1007/s11325-018-1756-x
doi:

Substances chimiques

Triiodothyronine 06LU7C9H1V
Thyrotropin 9002-71-5
Thyroxine Q51BO43MG4

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

963-967

Subventions

Organisme : The Endocrine Society of Thailand
ID : Not applicable
Organisme : Mahidol University
ID : Not applicable

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Auteurs

Chutintorn Sriphrapradang (C)

Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok, 10400, Thailand. chutins@gmail.com.

Sittichai Pinyopodjanard (S)

Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok, 10400, Thailand.

Onnicha Suntornlohanakul (O)

Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok, 10400, Thailand.

Hataikarn Nimitphong (H)

Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok, 10400, Thailand.

Naricha Chirakalwasan (N)

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Excellence Center for Sleep Disorders, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.

Sunee Saetang (S)

Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok, 10400, Thailand.

Thunyarat Anothaisintawee (T)

Department of Family Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Nantaporn Siwasaranond (N)

Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok, 10400, Thailand.

Areesa Manodpitipong (A)

Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok, 10400, Thailand.

La-Or Chailurkit (LO)

Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok, 10400, Thailand.

Sirimon Reutrakul (S)

Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok, 10400, Thailand.
Division of Endocrinology, Diabetes and Metabolism, University of Illinois at Chicago, Chicago, IL, USA.

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