Comment diagnostiquer un déséquilibre hormonal hypophysaire ?

Des tests sanguins et des examens d'imagerie comme l'IRM sont utilisés.

Quels tests sont utilisés pour mesurer les hormones hypophysaires ?

Les dosages sanguins des hormones comme ACTH, TSH et GH sont courants.

Quels symptômes indiquent un problème hypophysaire ?

Fatigue, troubles de la croissance, et irrégularités menstruelles peuvent indiquer un problème.

Comment l'imagerie aide-t-elle au diagnostic ?

L'IRM permet de visualiser les tumeurs ou anomalies de l'hypophyse.

Quels médecins consultent pour des problèmes hypophysaires ?

Les endocrinologues et neurologues sont les spécialistes concernés.

Quels sont les symptômes d'une hyperproduction d'hormones ?

Les symptômes incluent l'acromégalie, l'obésité et l'hypertension.

Quels signes indiquent une insuffisance hypophysaire ?

Fatigue, perte de libido, et troubles de la croissance sont des signes fréquents.

Comment les troubles menstruels sont-ils liés aux hormones hypophysaires ?

Les déséquilibres hormonaux peuvent provoquer des irrégularités menstruelles.

Quels symptômes sont associés à l'hyperprolactinémie ?

L'hyperprolactinémie peut causer des galactorrhées et des troubles menstruels.

Quels symptômes peuvent indiquer un adénome hypophysaire ?

Maux de tête, troubles de la vision et changements hormonaux sont des indicateurs.

Peut-on prévenir les troubles hypophysaires ?

Il n'existe pas de méthode de prévention spécifique, mais un suivi médical régulier aide.

Comment un mode de vie sain influence-t-il la santé hypophysaire ?

Une alimentation équilibrée et l'exercice régulier peuvent soutenir la santé hormonale.

Les examens réguliers sont-ils importants ?

Oui, des examens réguliers peuvent détecter précocement des anomalies hypophysaires.

Quel rôle joue la gestion du stress ?

La gestion du stress peut aider à maintenir un équilibre hormonal optimal.

Les antécédents familiaux influencent-ils le risque ?

Oui, des antécédents familiaux de troubles hormonaux peuvent augmenter le risque.

Quels traitements existent pour les troubles hypophysaires ?

Les traitements incluent la médication, la chirurgie et la radiothérapie.

Comment traiter l'hyperprolactinémie ?

Des médicaments comme les agonistes de la dopamine sont souvent prescrits.

Quelles sont les options chirurgicales pour les adénomes ?

La chirurgie transsphénoïdale est couramment utilisée pour retirer les adénomes.

Quel rôle joue la radiothérapie dans le traitement ?

La radiothérapie est utilisée pour traiter les tumeurs hypophysaires non résécables.

Comment les hormones de remplacement sont-elles utilisées ?

Elles sont prescrites pour compenser les déficits hormonaux après une insuffisance.

Quelles complications peuvent survenir avec un adénome hypophysaire ?

Des complications incluent des troubles visuels et des maux de tête persistants.

Comment l'insuffisance hypophysaire affecte-t-elle la santé ?

Elle peut entraîner des problèmes de croissance, de reproduction et de métabolisme.

Quels risques sont associés à une hyperproduction d'hormones ?

L'hyperproduction peut causer des maladies cardiovasculaires et des diabètes.

Quelles sont les conséquences d'un traitement inapproprié ?

Un traitement inapproprié peut aggraver les symptômes et causer des effets secondaires.

Les troubles hormonaux peuvent-ils affecter la santé mentale ?

Oui, des déséquilibres hormonaux peuvent contribuer à des troubles de l'humeur.

Quels facteurs augmentent le risque de troubles hypophysaires ?

Les antécédents familiaux, l'obésité et le stress sont des facteurs de risque connus.

Le vieillissement influence-t-il la santé hypophysaire ?

Oui, le vieillissement peut affecter la production hormonale et la fonction hypophysaire.

Les maladies auto-immunes sont-elles un facteur de risque ?

Oui, certaines maladies auto-immunes peuvent affecter la fonction hypophysaire.

Le mode de vie peut-il influencer le risque hormonal ?

Un mode de vie malsain, comme une mauvaise alimentation, augmente le risque.

Les traitements antérieurs affectent-ils le risque ?

Oui, certains traitements médicaux peuvent avoir des effets secondaires sur l'hypophyse.

Hormones hypophysaires - Informations médicales vérifiées

Prevalence of pituitary hormone dysfunction following radiotherapy for sinonasal and nasopharyngeal malignancies.

10 2023

DOI: 10.1002/hed.27476 PMID: 37534890

There are limited studies and no surveillance protocols on pituitary dysfunction for adults who underwent anterior skull base radiation.... Cross-sectional study of 50 consecutive patients with sinonasal or nasopharyngeal cancer who underwent definitive radiotherapy. The mean radiation doses, prevalence of pituitary dysfunction, and assoc... Pituitary hormone levels were abnormal in 23 (46%) patients, including 6 (12%) with symptomatic abnormalities requiring treatment. The most common hormonal abnormality was hyperprolactinemia (30%), ce... Nearly half of the patients had abnormal pituitary function, including over a tenth requiring treatment. There may be a dose-dependent association between hormonal dysfunction and radiation....

Adult Humans Nasopharyngeal Neoplasms Prevalence Cross-Sectional Studies +3 autres

Clinico-radiological correlation of pituitary stalk interruption syndrome in children with growth hormone deficiency.

Oct 2023

DOI: 10.1007/s11102-023-01351-2 PMID: 37695468

To analyze the clinical, hormonal, and radiological characteristics of Pituitary stalk interruption syndrome (PSIS) in children with growth hormone deficiency (GHD).... This is a prospective cross-sectional study, conducted over a period of three years in a short stature clinic of tertiary care referral hospital. 57 severe short stature children with proven GHD were ... Among 57 children with GHD, 14 (24%) were diagnosed as PSIS. The mean age at diagnosis was 11.8 ± 2.6years. The male to female ratio was 2.5:1. Nine (64%) children had multiple pituitary hormone defic... Male gender, breech presentation, external congenital anomalies like cryptorchidism, midline defects and nystagmus were more common in children with PSIS. MPHD were more frequently seen in PSIS wherea...

Adolescent Child Female Humans Male +9 autres

Blood concentrations of anterior pituitary hormones in drug-naïve people with first-episode psychosis: A systematic review and meta-analysis.

12 2023

DOI: 10.1016/j.psyneuen.2023.106392 PMID: 37778198

The role of anterior pituitary hormones - i.e., adrenocorticotropic hormone (ACTH), luteinizing and follicle stimulating hormones (LH and FSH), growth hormone (GH), prolactin (PRL), and thyroid-stimul... We searched Embase, MEDLINE, and PsycInfo for articles indexed until September 2022. Data quality was appraised. Random-effects meta-analyses were carried out, generating pooled standardized mean diff... Twenty-six studies were included. Drug-naïve people with FEP, compared to healthy subjects, had higher blood concentrations of ACTH (k = 7; N = 548; SMD = 0.62; 95%CI: 0.29 to 0.94; p < 0.001; I... Drug-naïve people with FEP have altered ACTH, PRL, and TSH blood concentrations, supporting the hypothesis that an abnormal anterior pituitary hormone secretion may be involved in the onset of schizop...

Humans Prolactin Growth Hormone Follicle Stimulating Hormone Thyrotropin +4 autres

Pituitary function at presentation and following therapy in patients with non-functional pituitary macroadenomas: a single centre retrospective cohort study.

10 2023

DOI: 10.1007/s12020-023-03434-3 PMID: 37389717

Non-functioning pituitary macroadenomas (NFPMs) may present with hypopituitarism. Pituitary surgery and radiotherapy pose an additional risk to pituitary function.... To assess the incidence of hypopituitarism at presentation, the impact of treatment, and the likelihood of endocrine recovery during follow-up.... All patients treated surgically with and without radiotherapy for NFPMs between 1987 and 2018 who had longer than six months follow-up were identified. Demographics, presentation, investigation, treat... In total, 383 patients were identified. The median age was 57 years, with a median follow-up of 8 years. Preoperatively, 227 patients (227/375; 61%) had evidence of at least one pituitary deficiency. ... NFPMs are associated with a significant degree of hypopituitarism at time of diagnosis and post-therapy. The combination of surgery and radiotherapy is associated with a higher risk of pituitary dysfu...

Male Humans Middle Aged Retrospective Studies Hypopituitarism +4 autres

Pituitary crosstalk with bone, adipose tissue and brain.

Dec 2023

DOI: 10.1038/s41574-023-00894-5 PMID: 37715028

Traditional textbook physiology has ascribed unitary functions to hormones from the anterior and posterior pituitary gland, mainly in the regulation of effector hormone secretion from endocrine organs...

Humans Pituitary Hormones Pituitary Gland Prolactin Adipose Tissue +1 autres

A case of osteogenesis imperfecta caused by a COL1A1 variant, coexisting with pituitary stalk interruption syndrome.

28 Aug 2023

DOI: 10.1507/endocrj.EJ22-0564 PMID: 37183013

Osteogenesis imperfecta (OI) is a rare hereditary bone fragility disorder that affects 6-7 per 100,000 populations, and pituitary stalk interruption syndrome (PSIS) is a rare congenital defect with va...

Male Adolescent Humans Child Middle Aged +5 autres

Management of Neonatal Isolated and Combined Growth Hormone Deficiency: Current Status.

14 Jun 2023

DOI: 10.3390/ijms241210114 PMID: 37373261

Congenital growth hormone deficiency (GHD) is a rare disease caused by disorders affecting the morphogenesis and function of the pituitary gland. It is sometimes found in isolation but is more frequen...

Infant, Newborn Humans Hypopituitarism Human Growth Hormone Pituitary Hormones +2 autres

Clinical Characteristics of Children with Combined Pituitary Hormone Deficiency and the Effects of Growth Hormone Treatment.

04 Dec 2023

DOI: 10.1055/a-2186-9304 PMID: 38049102

We aimed to describe the clinical characteristics of patients with congenital combined pituitary hormone deficiency (CPHD) and evaluate the first-year growth responses of individuals with CPHD and iso... This retrospective study was conducted in four tertiary care centers in Turkey. The records of patients diagnosed with CPHD (n=39) and severe IGHD (n=50) were collected. Cases with acquired lesions or... Among 39 patients (13 females; 33%) with a diagnosis of CPHD, the majority of patients (64%) presented initially with combined deficits at baseline examination, whereas isolated deficiencies (36%) wer... We established the nature and timing of numerous hormonal deficits emerging over time. We also identified that the existence of CPHD did not hinder growth response....

Suicides in National Hormone Pituitary Program Recipients of Cadaver-Derived Human Growth Hormone.

02 Nov 2023

DOI: 10.1210/jendso/bvad130 PMID: 38024647

Numerous reports of suicide among individuals who received cadaver-derived human growth hormone (c-hGH) through the National Hormone Pituitary Program (NHPP) raised the alarm for potentially increased... We conducted a study to assess suicide risk in the NHPP cohort and identify contributing factors to facilitate early recognition and intervention.... The study population consisted of patients receiving NHPP c-hGH starting from 1957, and cohort deaths with an ICD code consistent with suicide or possible suicide through 2020 were evaluated. Descript... Among 6272 patients there were 1200 all-cause cohort deaths, of which 55 (52 male, 3 female) were attributed to suicide. Of these, 47 were identified by ICD code alone compared to an expected count of... Overall, the observed number of suicides among NHPP c-hGH recipients was not significantly higher than expected. However, certain subgroups may be at elevated risk of suicide. Studies are needed to be...

Stereotactic radiosurgery for non-functioning pituitary tumor: a multicenter study of new pituitary hormone deficiency.

14 Dec 2023

DOI: 10.1093/neuonc/noad215 PMID: 38095431

Stereotactic radiosurgery (SRS) is used to treat recurrent or residual nonfunctioning pituitary neuroendocrine tumors (NFPA). The objective of the study was to assess imaging and development of new pi... Patients treated with single-session SRS for a NFPA were included in this retrospective, multicenter study. Tumor control and new pituitary dysfunction were evaluated using Cox analysis and Kaplan-Mei... 869 patients (male 476 [54.8%], median age at SRS 52.5 years [Interquartile range (IQR):18.9]) were treated using a median margin dose of 14Gy (IQR:4) for a median tumor volume of 3.4 cc (IQR: 4.3). W... SRS provides long-term tumor control with a 15.3% risk of hypopituitarism at 10 years....

Hormones hypophysaires : Questions médicales fréquentes

Questions fréquentes et termes MeSH associés

Diagnostic 5

Symptômes 5

Prévention 5

Traitements 5

Complications 5

Facteurs de risque 5

Contenu validé par Dr Olivier Menir

Sous-catégories

Hormones antéhypophysaires

Hormones post-hypophysaires

Gonadotrophines hypophysaires

Hormone de croissance

Prolactine

Thyréostimuline

Ocytocine

Vasotocine

Hormone folliculostimulante

Hormone lutéinisante

Hormone de croissance humaine

Sous-unité bêta de la thyrotropine

Sous-unité bêta de l'hormone folliculostimulante

Sous-unité bêta de l'hormone lutéinisante

Urofollitropine

Auteurs principaux

Sources (5526 au total)