Impact of menopausal hormone formulations on pituitary-ovarian regulatory feedback.
Administration, Cutaneous
Double-Blind Method
Estradiol
/ administration & dosage
Estrogen Replacement Therapy
Estrogens
/ administration & dosage
Female
Follicle Stimulating Hormone
/ blood
Humans
Luteinizing Hormone
/ blood
Menopause
/ physiology
Middle Aged
Ovary
/ drug effects
Pituitary Gland
/ drug effects
Progesterone
/ blood
androgen
estrogen
follicle-stimulating hormone
hormone therapy
menopause
pituitary-ovarian hormones
Journal
American journal of physiology. Regulatory, integrative and comparative physiology
ISSN: 1522-1490
Titre abrégé: Am J Physiol Regul Integr Comp Physiol
Pays: United States
ID NLM: 100901230
Informations de publication
Date de publication:
01 12 2019
01 12 2019
Historique:
pubmed:
31
10
2019
medline:
21
4
2020
entrez:
31
10
2019
Statut:
ppublish
Résumé
Changes in pituitary-ovarian hormones across the menopausal transition have multiple physiological consequences. However, little is known about how the major types of postmenopausal hormone therapy (HT) affect pituitary-ovarian hormonal relationships. This study evaluated these relationships in recently menopausal women (52.45 ± 2.49 yr of age) in the Kronos Early Estrogen Prevention Study (KEEPS) who were compliant to randomized, double-blinded treatment with oral conjugated equine estrogen (o-CEE;
Identifiants
pubmed: 31663769
doi: 10.1152/ajpregu.00234.2019
pmc: PMC6957372
doi:
Substances chimiques
Estrogens
0
Progesterone
4G7DS2Q64Y
Estradiol
4TI98Z838E
Luteinizing Hormone
9002-67-9
Follicle Stimulating Hormone
9002-68-0
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
R912-R920Subventions
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG028084
Pays : United States
Organisme : NIA NIH HHS
ID : RF1 AG057547
Pays : United States
Organisme : NIA NIH HHS
ID : U54 AG044170
Pays : United States
Organisme : NIA NIH HHS
ID : P30 AG019610
Pays : United States
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