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Système nerveux
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Axe hypothalamohypophysaire
Axe hypothalamohypophysaire : Questions médicales fréquentes
Diagnostic
5
Dysfonctionnement hormonal
Imagerie par résonance magnétique
Cortisol
Thyroid Stimulating Hormone
Troubles de l'appétit
Cycles menstruels
Endocrinologie
Symptômes hormonaux
Imagerie par résonance magnétique
Hypophyse
Symptômes
5
Hyperthyroïdisme
Palpitations
Hypopituitarisme
Troubles de croissance
Syndrome de Cushing
Hypertension
Prévention
5
Prévention
Alimentation équilibrée
Bilan hormonal
Détection précoce
Exercice physique
Santé hormonale
Antécédents familiaux
Risque
Traitements
5
Hyperprolactinémie
Cabergoline
Hormone de croissance
Traitement hormonal
Hypothyroïdie
Lévothyroxine
Syndrome de Cushing
Chirurgie
Hypopituitarisme
Hormones de remplacement
Complications
5
Hypopituitarisme
Insuffisance surrénalienne
Traitement inapproprié
Complications
Médicaments hormonaux
Effets secondaires
Facteurs de risque
5
Hypopituitarisme
Tumeurs hypophysaires
Stress
Axe hypothalamohypophysaire
Maladies auto-immunes
Axe hormonal
Obésité
Régulation hormonale
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"text": "Des tests hormonaux et des IRM peuvent aider à diagnostiquer les troubles."
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"position": 2,
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}
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"name": "Quels symptômes indiquent un problème hypothalamique ?",
"position": 3,
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"name": "Quand consulter un endocrinologue ?",
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"position": 7,
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{
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"position": 8,
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"name": "Quels symptômes sont liés à l'hypopituitarisme ?",
"position": 9,
"acceptedAnswer": {
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"text": "Fatigue, perte de libido et troubles de croissance peuvent indiquer l'hypopituitarisme."
}
},
{
"@type": "Question",
"name": "Comment reconnaître un syndrome de Cushing ?",
"position": 10,
"acceptedAnswer": {
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"text": "Obésité centrale, vergetures et hypertension sont des signes du syndrome de Cushing."
}
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{
"@type": "Question",
"name": "Peut-on prévenir les troubles hormonaux ?",
"position": 11,
"acceptedAnswer": {
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"text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à prévenir certains troubles."
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{
"@type": "Question",
"name": "Comment éviter le stress sur l'axe hypothalamique ?",
"position": 12,
"acceptedAnswer": {
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"text": "Des techniques de gestion du stress comme la méditation peuvent être bénéfiques."
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{
"@type": "Question",
"name": "Les examens réguliers sont-ils importants ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des bilans hormonaux réguliers peuvent aider à détecter des anomalies précocement."
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"@type": "Question",
"name": "L'exercice physique aide-t-il l'axe hormonal ?",
"position": 14,
"acceptedAnswer": {
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{
"@type": "Question",
"name": "Faut-il surveiller les antécédents familiaux ?",
"position": 15,
"acceptedAnswer": {
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"text": "Oui, des antécédents familiaux de troubles hormonaux peuvent augmenter le risque."
}
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"@type": "Question",
"name": "Quels traitements pour l'hyperprolactinémie ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les agonistes de la dopamine comme la cabergoline sont souvent prescrits."
}
},
{
"@type": "Question",
"name": "Comment traiter un déficit en hormone de croissance ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des injections d'hormone de croissance recombinante sont utilisées pour le traitement."
}
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"position": 18,
"acceptedAnswer": {
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"text": "La lévothyroxine est le traitement standard pour l'hypothyroïdie."
}
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"name": "Comment gérer le syndrome de Cushing ?",
"position": 19,
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"position": 20,
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"name": "Quelles complications peuvent survenir avec l'hypopituitarisme ?",
"position": 21,
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"text": "Des complications incluent l'insuffisance surrénalienne et des troubles métaboliques."
}
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"@type": "Question",
"name": "Quels risques avec un excès de cortisol ?",
"position": 22,
"acceptedAnswer": {
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"text": "Un excès de cortisol peut entraîner le diabète, l'hypertension et des infections."
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"@type": "Question",
"name": "Comment l'hyperthyroïdie affecte-t-elle le cœur ?",
"position": 23,
"acceptedAnswer": {
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"text": "Elle peut provoquer des arythmies et une hypertension, augmentant le risque cardiaque."
}
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"@type": "Question",
"name": "Quelles sont les conséquences d'un traitement inapproprié ?",
"position": 24,
"acceptedAnswer": {
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"text": "Un traitement inapproprié peut aggraver les symptômes et entraîner des complications graves."
}
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{
"@type": "Question",
"name": "Quels effets secondaires des médicaments hormonaux ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les effets secondaires peuvent inclure des nausées, des maux de tête et des changements d'humeur."
}
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"@type": "Question",
"name": "Quels facteurs augmentent le risque d'hypopituitarisme ?",
"position": 26,
"acceptedAnswer": {
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"text": "Les antécédents de tumeurs hypophysaires ou de radiothérapie augmentent le risque."
}
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{
"@type": "Question",
"name": "Le stress est-il un facteur de risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut perturber l'axe hypothalamohypophysaire."
}
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{
"@type": "Question",
"name": "L'âge influence-t-il les troubles hormonaux ?",
"position": 28,
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"@type": "Answer",
"text": "Oui, le risque de troubles hormonaux augmente avec l'âge."
}
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{
"@type": "Question",
"name": "Les maladies auto-immunes sont-elles un risque ?",
"position": 29,
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"text": "Oui, certaines maladies auto-immunes peuvent affecter l'axe hormonal."
}
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"@type": "Question",
"name": "Y a-t-il un lien avec l'obésité ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'obésité peut perturber la régulation hormonale et augmenter le risque de troubles."
}
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 10/04/2025
Contenu vérifié selon les dernières recommandations médicales
5 publications dans cette catégorie
Affiliations :
Pituitary Unit, Department of Endocrinology, Fondazione A Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Publications dans "Axe hypothalamohypophysaire" :
5 publications dans cette catégorie
Affiliations :
Pituitary Unit, Department of Endocrinology, Fondazione A Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy. Electronic address: Laura.DeMarinis@unicatt.it.
Publications dans "Axe hypothalamohypophysaire" :
4 publications dans cette catégorie
Affiliations :
Department of Radiology, Istituto Dermopatico dell'Immacolata, Rome and Università Cattolica del Sacro Cuore, Rome, Italy.
Publications dans "Axe hypothalamohypophysaire" :
4 publications dans cette catégorie
Affiliations :
Pituitary Unit, Department of Endocrinology, Fondazione A Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Publications dans "Axe hypothalamohypophysaire" :
4 publications dans cette catégorie
Affiliations :
Pituitary Unit, Department of Endocrinology, Fondazione A Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Publications dans "Axe hypothalamohypophysaire" :
4 publications dans cette catégorie
Affiliations :
Pituitary Unit, Department of Endocrinology, Fondazione A Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopaedics Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopaedics Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopaedics Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopaedics Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopaedics Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopaedics Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Division of Brain and Neurophysiology, Department of Physiology, Jichi Medical University, Shimotsuke, Japan.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Publications dans "Axe hypothalamohypophysaire" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopaedics Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Publications dans "Axe hypothalamohypophysaire" :
Psoriasis is an immune-mediated, chronic inflammatory disease affecting mainly the skin. Chronic stress leads to the blunted hypothalamic-pituitary-adrenal axis (HPA) that might induce pro-inflammator...
This cross-sectional study included 45 patients with psoriasis and 45 age and gender-matched apparently healthy volunteers (n = 45). IL-17, cortisol, and adrenocorticotrophic hormone (ACTH) levels wer...
Patients with psoriasis had higher levels of IL-17 and ACTH and lower levels of cortisol, as compared to controls. Stress scores (PSS, PSLE & DHUS) were significantly elevated in cases, as compared to...
Psoriasis patients having high ACTH, IL-17 and stress scores had lower levels of cortisol, indicating a dysregulated HPA axis with the pro-inflammatory state. This might lead to exacerbation of psoria...
JOURNAL/nrgr/04.03/01300535-202410000-00026/figure1/v/2024-02-06T055622Z/r/image-tiff Previous studies have shown that growth hormone can regulate hypothalamic energy metabolism, stress, and hormone r...
Hypophysitis is considered a rare inflammatory disease of the pituitary gland. For a long time, primary autoimmune hypophysitis has stood out as the most relevant type of hypophysitis. However, with t...
In this review, we discuss the epidemiology, diagnosis, and treatment of hypophysitis with a focus on recent data and highlight subtypes of particular interest while recognizing the gaps in knowledge ...
Regardless of cause, symptoms and signs of hypophysitis may be related to mass effect (headache and visual disturbance) and hormonal disruption that warrant prompt evaluation. In the vast majority of ...
Although subtle differences currently exist in management and outcome expectations between primary and secondary causes of hypophysitis, universally, treatment is aimed at symptom management and hormo...
This study aimed to investigate the effects of post-traumatic stress, caused by a strong earthquake, on the hypothalamo-pituitary-adrenal axis (HPA) and autonomous nervous system activity (ANS). Activ...
Kisspeptin is an endogenous peptide hormone that is the most potent stimulator of the hypothalamo-pituitary-gonadal (HPG) axis. The HPG axis can be suppressed by the activation of the hypothalamo-pitu...
Hypophysitis can clinically and radiologically mimic other nonfunctioning masses of the sella turcica, complicating preoperative diagnosis. While sellar masses may be treated surgically, hypophysitis ...
A thorough literature review identified published hypophysitis cases, which were compared to a retrospective group of non-functioning pituitary adenomas (NFA) from our institution. A preoperative hypo...
Fifty-six pathologically confirmed hypophysitis cases were identified in the literature. After excluding individual cases with missing values, 18 hypophysitis cases were compared to an age- and sex-ma...
The proposed scoring system may aid preoperative diagnosis of hypophysitis, preventing unnecessary surgery in these patients....
Kisspeptin is an important hormone involved in the stimulation of the hypothalamo-pituitary gonadal (HPG) axis. The HPG axis can be suppressed in certain conditions such as stress, which gives rise to...
Posttraumatic stress disorder (PTSD) does not only have direct consequences for well-being, but it also comes with a significant risk for severe somatic health consequences. A number of previous studi...
Immune checkpoint inhibitors (ICIs) are revolutionary in oncology but may cause immune-related (IR) side effects, such as hypophysitis. Treatment with anti-PD-(L)1, anti-CTLA-4 or anti-CLTA-4/PD-1 may...
retrospective analysis of 67 patients (27 anti-PD-(L)1, 6 anti-CLTA-4 and 34 anti-CTLA-4/PD-1 induced hypophysitis)....
The median time between starting ICIs and IR-hypophysitis was longer after anti-PD(L)-1) therapy (22 weeks versus 11 and 14 weeks after anti-CTLA-4 and anti-CTLA-4/PD-1 therapy, respectively). The maj...
The clinical presentation of IR-hypophysitis varies depending on the type of ICIs. MRI abnormalities were only seen in anti-CTLA-4 or anti-CTLA-4/PD-1 induced hypophysitis. Endocrine recovery is seen ...
An unhealthy lifestyle has a critical role in the pathogenesis and course of several chronic disorders. It has been hypothesized that lifestyle may also impact biological systems involved in stress re...