Apo-Opsin Exists in Equilibrium Between a Predominant Inactive and a Rare Highly Active State.


Journal

The Journal of neuroscience : the official journal of the Society for Neuroscience
ISSN: 1529-2401
Titre abrégé: J Neurosci
Pays: United States
ID NLM: 8102140

Informations de publication

Date de publication:
09 01 2019
Historique:
received: 02 08 2018
revised: 30 10 2018
accepted: 04 11 2018
pubmed: 22 11 2018
medline: 17 10 2019
entrez: 22 11 2018
Statut: ppublish

Résumé

Bleaching adaptation in rod photoreceptors is mediated by apo-opsin, which activates phototransduction with effective activity 10

Identifiants

pubmed: 30459230
pii: JNEUROSCI.1980-18.2018
doi: 10.1523/JNEUROSCI.1980-18.2018
pmc: PMC6325258
doi:

Substances chimiques

Rod Opsins 0
Rhodopsin 9009-81-8
retinoid isomerohydrolase EC 3.1.1.64
cis-trans-Isomerases EC 5.2.-
Retinaldehyde RR725D715M

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

212-223

Subventions

Organisme : NEI NIH HHS
ID : R01 EY009339
Pays : United States
Organisme : NEI NIH HHS
ID : P30 EY002687
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY019312
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY025214
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY030912
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY025696
Pays : United States

Informations de copyright

Copyright © 2019 the authors 0270-6474/19/390212-12$15.00/0.

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Auteurs

Shinya Sato (S)

Department of Ophthalmology and Visual Sciences, Washington University in St. Louis, St. Louis, Missouri 63110 and.

Beata Jastrzebska (B)

Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106.

Andreas Engel (A)

Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106.

Krzysztof Palczewski (K)

Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106.

Vladimir J Kefalov (VJ)

Department of Ophthalmology and Visual Sciences, Washington University in St. Louis, St. Louis, Missouri 63110 and kefalov@wustl.edu.

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Classifications MeSH