A review of non-invasive insulin delivery systems for diabetes therapy in clinical trials over the past decade.


Journal

Drug discovery today
ISSN: 1878-5832
Titre abrégé: Drug Discov Today
Pays: England
ID NLM: 9604391

Informations de publication

Date de publication:
02 2019
Historique:
received: 14 09 2018
revised: 19 10 2018
accepted: 15 11 2018
pubmed: 23 11 2018
medline: 1 8 2019
entrez: 23 11 2018
Statut: ppublish

Résumé

At present, the main form of insulin administration is the invasive subcutaneous (s.c.) route and, for many patients, this means managing their glucose levels with multiple daily injections, which is both painful and difficult to administer chronically. To increase patient compliance, products are slowly reaching the market that are more patient friendly, such as the insulin patch-pump systems, including Omnipod and V-Go, but also the inhaled-insulin Afrezza

Identifiants

pubmed: 30465877
pii: S1359-6446(18)30254-X
doi: 10.1016/j.drudis.2018.11.010
pii:
doi:

Substances chimiques

Hypoglycemic Agents 0
Insulin 0

Types de publication

Journal Article Review

Langues

eng

Pagination

440-451

Informations de copyright

Copyright © 2018 Elsevier Ltd. All rights reserved.

Auteurs

Najma Easa (N)

School of Life Sciences, Pharmacy & Chemistry, Kingston University, London, KT1 2EE, UK.

Raid G Alany (RG)

School of Life Sciences, Pharmacy & Chemistry, Kingston University, London, KT1 2EE, UK.

Mark Carew (M)

School of Life Sciences, Pharmacy & Chemistry, Kingston University, London, KT1 2EE, UK.

Anil Vangala (A)

School of Life Sciences, Pharmacy & Chemistry, Kingston University, London, KT1 2EE, UK. Electronic address: a.vangala@kingston.ac.uk.

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Classifications MeSH