Effects of supplementation of chromium histidinate on glucose, lipid metabolism and oxidative stress in cats.
Animal Feed
/ analysis
Animal Nutritional Physiological Phenomena
Animals
Blood Glucose
Cats
Diet
/ veterinary
Dietary Supplements
Female
Glucose Tolerance Test
Histidine
/ analogs & derivatives
Lipid Metabolism
/ drug effects
Male
Organometallic Compounds
/ chemistry
Oxidative Stress
/ drug effects
cats
chromium histidinate
glucose metabolism
glucose tolerance
lipid metabolism
oxidative stress
Journal
Journal of animal physiology and animal nutrition
ISSN: 1439-0396
Titre abrégé: J Anim Physiol Anim Nutr (Berl)
Pays: Germany
ID NLM: 101126979
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
received:
02
11
2017
revised:
23
09
2018
accepted:
17
10
2018
pubmed:
24
11
2018
medline:
17
4
2019
entrez:
24
11
2018
Statut:
ppublish
Résumé
In recent years, two meta-analyses of chromium (Cr) supplementation have shown beneficial effects on glucose metabolism. Chromium histidinate (CrHis) reduces serum glucose levels in rats fed a high-fat diet but no study has been conducted on cats until now. The aim of this study was to examine the effects of CrHis on glucose and lipid metabolism in cats. To challenge the glucose metabolism, 16 cats were fed a high-carbohydrate high-fat diet for three months. One group (n = 8) received 800 ug CrHis per day for two months, while the other group (n = 8) served as control group. An oral glucose tolerance test was conducted, blood samples were taken, and biochemical parameters and oxidative stress were measured. CrHis serum levels were significantly increased (p = 0.027) in the treatment group, while fructosamine levels were significantly lower (p = 0.029) in the control group. In both groups, glucose (p < 0.01), b-hydroxy-butyrate (p = 0.024) and 8-hydroxy-deoxyguanosine (p = 0.028) levels decreased significantly and cholesterol levels increased significantly (p < 0.01). In conclusion, CrHis did not improve glucose or lipid metabolism and did not affect oxidative stress in healthy cats.
Identifiants
pubmed: 30467904
doi: 10.1111/jpn.13023
pmc: PMC7379520
doi:
Substances chimiques
Blood Glucose
0
Organometallic Compounds
0
chromium histidinate
1BY3EP7D99
Histidine
4QD397987E
Types de publication
Clinical Trial, Veterinary
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
331-338Informations de copyright
© 2018 Blackwell Verlag GmbH.
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