Clinical metric for differentiating intracranial hemangiopericytomas from meningiomas using diffusion weighted MRI.


Journal

Clinical imaging
ISSN: 1873-4499
Titre abrégé: Clin Imaging
Pays: United States
ID NLM: 8911831

Informations de publication

Date de publication:
Historique:
received: 05 01 2018
revised: 25 07 2018
accepted: 22 10 2018
pubmed: 24 11 2018
medline: 2 5 2019
entrez: 24 11 2018
Statut: ppublish

Résumé

Intracranial Hemangiopericytomas (IHP) are dural based tumors that frequently recur/metastasize. Unfortunately, their imaging appearance overlaps significantly with more benign meningiomas. We evaluated the use of diffusion weighted imaging (DWI) to differentiate IHP from meningioma. We compared MRI of IHP tumors (WHO Grades II/III) (n = 20) to meningioma (n = 48, WHO Grade I/II). ADC values differed between IHP (1.05 × 10-3 mm2/s) and meningiomas (0.89 × 10-3 mm2/s) (p = 0.05). Normalized ADC ratios (nADC), differed between IHP and meningiomas (1.30 vs 1.07, p = 0.03). Importantly, a nADC cutoff of >1.3 was specific (96%) but not sensitive (35%) for identifying IHP.

Identifiants

pubmed: 30469018
pii: S0899-7071(18)30288-2
doi: 10.1016/j.clinimag.2018.10.018
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-5

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Alexander M El-Ali (AM)

Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop Street, Suite 200 East Wing, Pittsburgh, PA 15213, USA.

Vikas Agarwal (V)

Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop Street, Suite 200 East Wing, Pittsburgh, PA 15213, USA. Electronic address: agarwalv@upmc.edu.

Andrew Thomas (A)

Riverside Radiology and Interventional Associates, Inc., 3525 Olentangy River R., Suite 5362, Columbus, OH 43214, USA.

Ronald L Hamilton (RL)

Department of Pathology, Division of Neuropathology, University of Pittsburgh Medical Center, 3550 Terrace Street, S724.1 Scaife Hall, Pittsburgh, PA 15261, USA.

Christopher G Filippi (CG)

Department of Radiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Lenox Hill Hospital, 100 East 77th Street, New York, NY 10075, USA.

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