Pulmonary and muscle profile in pneumosepsis: A temporal analysis of inflammatory markers.
IL-6
Muscle injury
NF-κB
Pulmonary inflammation
Sepsis
Journal
Cytokine
ISSN: 1096-0023
Titre abrégé: Cytokine
Pays: England
ID NLM: 9005353
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
received:
06
09
2018
revised:
06
11
2018
accepted:
12
11
2018
pubmed:
25
11
2018
medline:
27
3
2020
entrez:
25
11
2018
Statut:
ppublish
Résumé
In sepsis, greater understanding of the inflammatory mechanism involved would provide insights into the condition and into its extension to the muscular apparatus in critically ill patients. Therefore, this study evaluates the inflammatory profile of pneumosepsis induced by Klebsiella pneumoniae (K.p.) in lungs and skeletal muscles during the first 72 h. Male BALB/c mice were divided into 4 groups, submitted to intratracheal inoculation of K.p. at a concentration of 2 × 10
Identifiants
pubmed: 30470659
pii: S1043-4666(18)30424-1
doi: 10.1016/j.cyto.2018.11.012
pii:
doi:
Substances chimiques
Biomarkers
0
Cytokines
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
128-134Informations de copyright
Copyright © 2018 Elsevier Ltd. All rights reserved.