Sepsis in surgical patients: Burn sepsis.
Patients with large burn injuries remain a challenge. The loss of skin barrier integrity and induced immunosuppression after injury increases their vulnerability to infection. Sepsis remains the prima...
Sepsie : Questions médicales fréquentes
Questions fréquentes et termes MeSH associés
Diagnostic 5
#1
Comment diagnostiquer la sepsie ?
Le diagnostic repose sur des critères cliniques et des analyses sanguines, notamment la présence de bactéries.
#2
Quels tests sont utilisés pour la sepsie ?
Des hémocultures, des tests de fonction hépatique et rénale, et des marqueurs inflammatoires sont utilisés.
#3
Quels signes cliniques indiquent une sepsie ?
Fièvre, tachycardie, hypotension et altération de l'état mental sont des signes clés.
#4
Quelle est l'importance du score SOFA ?
Le score SOFA évalue la fonction organique et aide à déterminer la gravité de la sepsie.
#5
Quand suspecter une sepsie chez un patient ?
Suspectez une sepsie en cas d'infection suspectée avec des signes de défaillance organique.
Symptômes 5
#1
Quels sont les symptômes courants de la sepsie ?
Fièvre, frissons, confusion, respiration rapide et douleur intense sont fréquents.
#2
La sepsie peut-elle provoquer des changements mentaux ?
Oui, la confusion et la désorientation sont des symptômes neurologiques possibles.
#3
Comment la sepsie affecte-t-elle la respiration ?
Elle peut entraîner une respiration rapide et une détresse respiratoire due à l'inflammation.
#4
Quels signes vitaux sont altérés en sepsie ?
Tachycardie, hypotension et hyperthermie sont des signes vitaux souvent altérés.
#5
La douleur est-elle un symptôme de sepsie ?
Oui, une douleur intense, souvent abdominale ou musculaire, peut se manifester.
Prévention 5
#1
Comment prévenir la sepsie ?
La prévention passe par une bonne hygiène, la vaccination et le traitement rapide des infections.
#2
Les vaccinations aident-elles contre la sepsie ?
Oui, certaines vaccinations, comme celles contre la grippe et le pneumocoque, peuvent réduire le risque.
#3
Pourquoi est-il important de traiter les infections rapidement ?
Un traitement rapide des infections peut prévenir leur progression vers la sepsie.
#4
Les soins post-opératoires peuvent-ils prévenir la sepsie ?
Oui, des soins appropriés après une chirurgie réduisent le risque d'infections et de sepsie.
#5
Comment l'hygiène personnelle aide-t-elle ?
Une bonne hygiène personnelle réduit le risque d'infections, diminuant ainsi le risque de sepsie.
Traitements 5
#1
Quel est le traitement principal de la sepsie ?
Le traitement principal est l'administration rapide d'antibiotiques et de fluides intraveineux.
#2
Comment les fluides intraveineux aident-ils ?
Ils aident à maintenir la pression artérielle et à améliorer la perfusion des organes.
#3
Quand utiliser des vasopresseurs en sepsie ?
Les vasopresseurs sont utilisés si la pression artérielle reste basse malgré les fluides.
#4
La chirurgie est-elle nécessaire en sepsie ?
Oui, si une source d'infection localisée est identifiée, une intervention chirurgicale peut être nécessaire.
#5
Quels médicaments sont utilisés en cas de sepsie ?
Des antibiotiques à large spectre sont souvent administrés en urgence pour traiter l'infection.
Complications 5
#1
Quelles sont les complications possibles de la sepsie ?
Les complications incluent le choc septique, l'insuffisance organique et la mort.
#2
Le choc septique est-il une complication fréquente ?
Oui, le choc septique est une complication grave qui peut survenir en cas de sepsie avancée.
#3
Comment la sepsie affecte-t-elle les organes ?
Elle peut entraîner une défaillance multi-organique, affectant le cœur, les reins et les poumons.
#4
La sepsie peut-elle entraîner des amputations ?
Oui, dans les cas graves, des amputations peuvent être nécessaires en raison de nécrose tissulaire.
#5
Quels sont les effets à long terme de la sepsie ?
Les survivants peuvent souffrir de fatigue chronique, de troubles cognitifs et de problèmes psychologiques.
Facteurs de risque 5
#1
Qui est le plus à risque de sepsie ?
Les personnes âgées, immunodéprimées et celles avec des maladies chroniques sont plus à risque.
#2
Les infections récurrentes augmentent-elles le risque de sepsie ?
Oui, les infections récurrentes peuvent augmenter le risque de développer une sepsie.
#3
Le diabète est-il un facteur de risque pour la sepsie ?
Oui, le diabète peut affaiblir le système immunitaire, augmentant le risque de sepsie.
#4
Les interventions chirurgicales augmentent-elles le risque ?
Oui, les interventions chirurgicales peuvent introduire des infections, augmentant le risque de sepsie.
#5
Le tabagisme est-il un facteur de risque pour la sepsie ?
Oui, le tabagisme peut affaiblir le système immunitaire et augmenter le risque d'infections.
Contenu validé par Dr Olivier Menir
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 16/03/2026
Contenu vérifié selon les dernières recommandations médicales
Sous-catégories
9 au total
└─
Bactériémie
BacteremiaD016470 -
C23.550.470.790.500.100
└─
Fongémie
FungemiaD016469 -
C23.550.470.790.500.360
└─
Sepsis néonatal
Neonatal SepsisD000071074 -
C23.550.470.790.500.470
└─
Parasitémie
ParasitemiaD018512 -
C23.550.470.790.500.580
└─
Virémie
ViremiaD014766 -
C23.550.470.790.500.900
└─└─
Endotoxémie
EndotoxemiaD019446 -
C23.550.470.790.500.100.275
└─└─
Septicémie hémorragique
Hemorrhagic SepticemiaD006483 -
C23.550.470.790.500.100.375
└─└─
Candidémie
CandidemiaD058387 -
C23.550.470.790.500.360.150
└─└─
Septicémie hémorragique virale
Hemorrhagic Septicemia, ViralD031941 -
C23.550.470.790.500.900.400
Auteurs principaux
Luisa Agnello
2 publications dans cette catégorie
Affiliations :
- Department of Biomedicine, Neurosciences and Advanced Diagnostics, Institute of Clinical Biochemistry, Clinical Molecular Medicine and Laboratory Medicine, University of Palermo, 90127 Palermo, Italy.
Publications dans "Sepsie" :
-
Independent Validation of Sepsis Index for Sepsis Screening in the Emergency Department.
Diagnostics (Basel, Switzerland) 2021-07-19
-
Biomarkers of Sepsis.
Diagnostics (Basel, Switzerland) 2023-01-25
Marcello Ciaccio
2 publications dans cette catégorie
Affiliations :
- Department of Biomedicine, Neurosciences and Advanced Diagnostics, Institute of Clinical Biochemistry, Clinical Molecular Medicine and Laboratory Medicine, University of Palermo, 90127 Palermo, Italy.
- Department of Laboratory Medicine, University Hospital "P. Giaccone", 90127 Palermo, Italy.
Publications dans "Sepsie" :
-
Independent Validation of Sepsis Index for Sepsis Screening in the Emergency Department.
Diagnostics (Basel, Switzerland) 2021-07-19
-
Biomarkers of Sepsis.
Diagnostics (Basel, Switzerland) 2023-01-25
Ri Wen
2 publications dans cette catégorie
Affiliations :
- Department of Pediatrics, PICU, Shengjing Hospital of China Medical University, Shenyang 110004, China.
Publications dans "Sepsie" :
-
Role of sirtuins in sepsis and sepsis-induced organ dysfunction: A review.
International journal of biological macromolecules 2024-08-18
-
Molecular mechanisms and functions of pyroptosis in sepsis and sepsis-associated organ dysfunction.
Frontiers in cellular and infection microbiology 2022-07-29
Ni Yang
2 publications dans cette catégorie
Affiliations :
- Department of Pediatrics, PICU, Shengjing Hospital of China Medical University, Shenyang 110004, China.
Publications dans "Sepsie" :
-
Role of sirtuins in sepsis and sepsis-induced organ dysfunction: A review.
International journal of biological macromolecules 2024-08-18
-
Molecular mechanisms and functions of pyroptosis in sepsis and sepsis-associated organ dysfunction.
Frontiers in cellular and infection microbiology 2022-07-29
Tie-Ning Zhang
2 publications dans cette catégorie
Affiliations :
- Department of Pediatrics, PICU, Shengjing Hospital of China Medical University, Shenyang 110004, China. Electronic address: cmuztn@vip.qq.com.
Publications dans "Sepsie" :
-
Role of sirtuins in sepsis and sepsis-induced organ dysfunction: A review.
International journal of biological macromolecules 2024-08-18
-
Molecular mechanisms and functions of pyroptosis in sepsis and sepsis-associated organ dysfunction.
Frontiers in cellular and infection microbiology 2022-07-29
Claudia C Dos Santos
2 publications dans cette catégorie
Affiliations :
- Keenan and Li Ka Shing Knowledge Institute of Saint Michael's Hospital, Toronto, ON, Canada.
- Institute of Medical Sciences and Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada.
Publications dans "Sepsie" :
-
Epigenetics of Sepsis.
Critical care medicine
-
The plasma peptides of sepsis.
Clinical proteomics 2020-07-02
You Shang
2 publications dans cette catégorie
Affiliations :
- Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Publications dans "Sepsie" :
-
Nanomaterials targeting macrophages in sepsis: A promising approach for sepsis management.
Frontiers in immunology 2022-12-09
-
S100A8/A9: An emerging player in sepsis and sepsis-induced organ injury.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023-10-07
None None
2 publications dans cette catégorie
Publications dans "Sepsie" :
-
A PREDICTION MODEL FOR SEPSIS IN INFECTED PATIENTS: EARLY ASSESSMENT OF SEPSIS ENGAGEMENT.
Shock (Augusta, Ga.) 2023-07-12
-
Epidemiology of sepsis and septic shock in intensive care units between sepsis-2 and sepsis-3 populations: sepsis prognostication in intensive care unit and emergency room (SPICE-ICU).
Journal of intensive care 2020-06-30
Adam R Schertz
2 publications dans cette catégorie
Affiliations :
- Department of Internal Medicine, Section on Pulmonology, Critical Care, Allergy, and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Publications dans "Sepsie" :
-
Clinical Impact of a Sepsis Alert System Plus Electronic Sepsis Navigator Using the Epic Sepsis Prediction Model in the Emergency Department.
The Journal of emergency medicine 2023-03-08
-
Sepsis Prediction Model for Determining Sepsis vs SIRS, qSOFA, and SOFA.
JAMA network open 2023-08-01
Kristin M Lenoir
2 publications dans cette catégorie
Affiliations :
- Department of Biostatistics and Data Science, Division of Public Health Science, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Publications dans "Sepsie" :
-
Clinical Impact of a Sepsis Alert System Plus Electronic Sepsis Navigator Using the Epic Sepsis Prediction Model in the Emergency Department.
The Journal of emergency medicine 2023-03-08
-
Sepsis Prediction Model for Determining Sepsis vs SIRS, qSOFA, and SOFA.
JAMA network open 2023-08-01
Karl W Thomas
2 publications dans cette catégorie
Affiliations :
- Department of Internal Medicine, Section on Pulmonology, Critical Care, Allergy, and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Publications dans "Sepsie" :
-
Clinical Impact of a Sepsis Alert System Plus Electronic Sepsis Navigator Using the Epic Sepsis Prediction Model in the Emergency Department.
The Journal of emergency medicine 2023-03-08
-
Sepsis Prediction Model for Determining Sepsis vs SIRS, qSOFA, and SOFA.
JAMA network open 2023-08-01
Timothy G Buchman
2 publications dans cette catégorie
Affiliations :
- Biomedical Advanced Research and Development Authority, Office of the Assistant Secretary for Preparedness and Response, United States Department of Health and Human Services, Washington, DC.
- Emory Critical Care Center, Emory University, Atlanta, GA.
Publications dans "Sepsie" :
-
Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012-2018.
Critical care medicine
-
Sepsis Among Medicare Beneficiaries: 2. The Trajectories of Sepsis, 2012-2018.
Critical care medicine
Steven Q Simpson
2 publications dans cette catégorie
Affiliations :
- Biomedical Advanced Research and Development Authority, Office of the Assistant Secretary for Preparedness and Response, United States Department of Health and Human Services, Washington, DC.
- Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Kansas, Kansas City, KS.
Publications dans "Sepsie" :
-
Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012-2018.
Critical care medicine
-
Sepsis Among Medicare Beneficiaries: 2. The Trajectories of Sepsis, 2012-2018.
Critical care medicine
Kimberly L Sciarretta
2 publications dans cette catégorie
Affiliations :
- Biomedical Advanced Research and Development Authority, Office of the Assistant Secretary for Preparedness and Response, United States Department of Health and Human Services, Washington, DC.
Publications dans "Sepsie" :
-
Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012-2018.
Critical care medicine
-
Sepsis Among Medicare Beneficiaries: 2. The Trajectories of Sepsis, 2012-2018.
Critical care medicine
Kristen P Finne
2 publications dans cette catégorie
Affiliations :
- Office of the Assistant Secretary for Preparedness and Response, United States Department of Health and Human Services, Washington, DC.
Publications dans "Sepsie" :
-
Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012-2018.
Critical care medicine
-
Sepsis Among Medicare Beneficiaries: 2. The Trajectories of Sepsis, 2012-2018.
Critical care medicine
Nicole Sowers
2 publications dans cette catégorie
Affiliations :
- Acumen, LLC, Burlingame, CA.
Publications dans "Sepsie" :
-
Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012-2018.
Critical care medicine
-
Sepsis Among Medicare Beneficiaries: 2. The Trajectories of Sepsis, 2012-2018.
Critical care medicine
Michael Collier
2 publications dans cette catégorie
Affiliations :
- Acumen, LLC, Burlingame, CA.
Publications dans "Sepsie" :
-
Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012-2018.
Critical care medicine
-
Sepsis Among Medicare Beneficiaries: 2. The Trajectories of Sepsis, 2012-2018.
Critical care medicine
Saurabh Chavan
2 publications dans cette catégorie
Affiliations :
- Acumen, LLC, Burlingame, CA.
Publications dans "Sepsie" :
-
Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012-2018.
Critical care medicine
-
Sepsis Among Medicare Beneficiaries: 2. The Trajectories of Sepsis, 2012-2018.
Critical care medicine
Ibijoke Oke
2 publications dans cette catégorie
Affiliations :
- Acumen, LLC, Burlingame, CA.
Publications dans "Sepsie" :
-
Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012-2018.
Critical care medicine
-
Sepsis Among Medicare Beneficiaries: 2. The Trajectories of Sepsis, 2012-2018.
Critical care medicine
Meghan E Pennini
2 publications dans cette catégorie
Affiliations :
- Biomedical Advanced Research and Development Authority, Office of the Assistant Secretary for Preparedness and Response, United States Department of Health and Human Services, Washington, DC.
Publications dans "Sepsie" :
-
Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012-2018.
Critical care medicine
-
Sepsis Among Medicare Beneficiaries: 2. The Trajectories of Sepsis, 2012-2018.
Critical care medicine
Sources (3769 au total)
Evaluation of Sepsis-1 and Sepsis-3 Diagnostic Criteria in Patients with Sepsis in Intensive Care Unit.
The use of SIRS and SOFA criteria in diagnosing sepsis among patients has been characterized by increasingly growing criticism. Indeed, the definition of sepsis has attracted significant controversy i... The study used the Medical Information Mart for Intensive Care-III (MIMIC-III) database in assessing the effectiveness of the SIRS and SOFA diagnostic criteria. It ascertained the severity and specifi... The analysis of data for this study was based on the chi-square test, which is significant in comparing the specificity, mortality, and sensitivity of the data. The process of screening the MIMIC-III ... The study results also portray numerous challenges in using the sepsis-3 criteria as a diagnostic tool. In particular, the ICD-10-CM diagnosis approach was limiting because it inhibited the measure of...
Gasdermins in sepsis.
Sepsis is a hyper-heterogeneous syndrome in which the systemic inflammatory response persists throughout the course of the disease and the inflammatory and immune responses are dynamically altered at ...
A PREDICTION MODEL FOR SEPSIS IN INFECTED PATIENTS: EARLY ASSESSMENT OF SEPSIS ENGAGEMENT.
Purpose: To evaluate significant risk variables for sepsis incidence and develop a predictive model for rapid screening and diagnosis of sepsis in patients from the emergency department (ED). Methods:...
Sepsis Prediction Model for Determining Sepsis vs SIRS, qSOFA, and SOFA.
The Sepsis Prediction Model (SPM) is a proprietary decision support tool created by Epic Systems; it generates a predicting sepsis score (PSS). The model has not undergone validation against existing ... To assess the validity and timeliness of the SPM compared with SIRS, qSOFA, and SOFA.... This retrospective cohort study included all adults admitted to 5 acute care hospitals in a single US health system between June 5, 2019, and December 31, 2020. Data analysis was conducted from March ... A sepsis event was defined as receipt of 4 or more days of antimicrobials, blood cultures collected within ±48 hours of initial antimicrobial, and at least 1 organ dysfunction as defined by the organ ... Of 60 507 total admissions, 1663 (2.7%) met sepsis criteria, with 1324 electronic health record-confirmed sepsis (699 [52.8%] male patients; 298 [22.5%] Black patients; 46 [3.5%] Hispanic/Latinx patie... In this cohort study of hospital admissions, balanced accuracy of the SPM outperformed other models at higher threshold PSS; however, application of the SPM in a clinical setting was limited by poor t...
The immune landscape of sepsis and using immune clusters for identifying sepsis endotypes.
The dysregulated immune response to sepsis still remains unclear. Stratification of sepsis patients into endotypes based on immune indicators is important for the future development of personalized th... The indicators involved in innate, cellular, and humoral immune cells, inhibitory immune cells, and cytokines were simultaneously assessed in 90 sepsis patients and 40 healthy controls. Unsupervised k... We depicted that the impairment of innate and adaptive immunity accompanying increased inflammation was the most prominent feature in patients with sepsis. However, using immune indicators for disting... We depicted the immune landscape of patients with sepsis and identified three distinct immune endotypes with different survival rates. Cluster membership could be predicted with a model based on immun...
S100A8/A9: An emerging player in sepsis and sepsis-induced organ injury.
Sepsis, the foremost contributor to mortality in intensive care unit patients, arises from an uncontrolled systemic response to invading infections, resulting in extensive harm across multiple organs ...
Variable Levels of Oxytocin During Sepsis: The Role of Oxytocin in Sepsis Pathophysiology.
Although the role of oxytocin in the pathophysiology of sepsis is still unknown, rising preclinical evidence suggests that oxytocin is possibly involved. However, no direct clinical studies have measu... Twenty-two male patients over 18 years of age with a SOFA score of 2 points or more who were admitted to the ICU were included. Patients with a history of neuroendocrine, psychiatric, and neurologic d... Mean serum oxytocin level was higher at 6 h of ICU admission (41.27 ± 13.14 ng/L) than after 24 and 48 h of ICU admission (22.63 ± 5.75 and 20.97 ± 7.61 ng/L respectively) (... Our study, while reporting increased serum oxytocin levels in the initial phase of sepsis and decline afterward, supports the possible contribution of oxytocin in the pathophysiology of sepsis. Given ...
The role of neutrophil extracellular traps in sepsis and sepsis-related acute lung injury.
Neutrophils release neutrophil extracellular traps (NETs) to trap pathogenic microorganisms. NETs are involved in the inflammatory response and bacterial killing and clearance. However, their excessiv...
Do prehospital sepsis alerts decrease time to complete CMS sepsis measures?
In an effort to improve sepsis outcomes the Centers for Medicare and Medicaid Services (CMS) established a time sensitive sepsis management bundle as a core quality measure that includes blood culture... This study was a retrospective cohort study of patients transported via EMS from December 1, 2018 to December 1, 2019 who met the criteria of the Maryland Statewide EMS sepsis protocol and compared ou... Median time to achieve all four studied CMS sepsis core measures was 103 min [IQR 61-153] for patients who received a prehospital sepsis alert and 106.5 min [IQR 75-189] for patients who did not recei... This study questions the effectiveness of prehospital sepsis alert protocols on decreasing time to complete CMS sepsis core measures. Future studies should address if these times can be impacted by ha...