The association between hearing impairment and neural envelope encoding at different ages.
Age
Audibility
Envelope modulations
Hearing impairment
Neural synchronization
Journal
Neurobiology of aging
ISSN: 1558-1497
Titre abrégé: Neurobiol Aging
Pays: United States
ID NLM: 8100437
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
received:
23
03
2018
revised:
11
09
2018
accepted:
04
10
2018
pubmed:
26
11
2018
medline:
27
11
2019
entrez:
26
11
2018
Statut:
ppublish
Résumé
Hearing impairment goes with speech perception difficulties, presumably not only because of poor hearing sensitivity but also because of altered central auditory processing. Critical herein is temporal processing of the speech envelope, mediated by synchronization of neural activity to the envelope modulations. It has been suggested that hearing impairment is associated with enhanced sensitivity to envelope modulations which, in turn, relates to poorer speech perception. To verify this hypothesis, we performed a comparative electrophysiological study in hearing-impaired (HI) and normal-hearing (NH) human listeners of three age groups, investigating neural envelope encoding. HI young and middle-aged adults showed enhanced neural synchronization to envelope modulations relative to NH controls, particularly when stimulus audibility was corrected for. At an older age, the degree of neural synchronization was similar for HI and NH persons, yet HI persons showed a synchronization asymmetry toward the right hemisphere. This study demonstrates that hearing impairment is characterized by changes in the neural encoding of envelope modulations, the nature of which varies with age.
Identifiants
pubmed: 30472387
pii: S0197-4580(18)30372-5
doi: 10.1016/j.neurobiolaging.2018.10.008
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
202-212Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.