Yield of Echocardiography in the Evaluation of Cerebral Ischemic Events: A Single Center Cohort Study.


Journal

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
ISSN: 1532-8511
Titre abrégé: J Stroke Cerebrovasc Dis
Pays: United States
ID NLM: 9111633

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 15 05 2018
revised: 11 10 2018
accepted: 29 10 2018
pubmed: 27 11 2018
medline: 15 3 2019
entrez: 27 11 2018
Statut: ppublish

Résumé

Echocardiography (ECO) is frequently used as a screening test in patients with acute ischemic brain disease. We aimed to evaluate the additional information and therapeutic impact resulting from ECO in these patients. We conducted a prospective study performing ECO on consecutive patients with ischemic stroke or transient ischemic attacks, admitted to our centre between February 2013 and May 2017. A total of 696 patients were included (female, 57.3%; mean age, 70 ± 15.3 years). Seven hundred thirty two echocardiographic examinations were performed (696 transthoracic and 36 transesophageal). Echocardiography yielded findings judged of clinical importance in 142 patients (20.4%, 95% CI 17.5-23.5). The most frequent of these were left atrial volume enlargement or a normal evaluation. Echocardiography findings resulted in changes in the management of 76 patients (10.7% 95% CI 8.8-13.4); initiation of anticoagulation therapy, administration of IV antibiotic therapy, cardiac surgeries, or other pharmacological therapies occurring in 42 cases (6%). The presence of coronary heart disease (OR: 2.64 95% CI 1.34-5.25), atrial fibrillation (OR: 0.24; 95% CI, 0.2-0.69), and admission NIHSS (OR: 1.04; 95% CI, 1.01-1.09), were the variables associated with changes in management. In unselected patients with acute ischemic stroke ECO had a low yield of additional information, and it changed management in a small percentage of patients.

Sections du résumé

BACKGROUND BACKGROUND
Echocardiography (ECO) is frequently used as a screening test in patients with acute ischemic brain disease. We aimed to evaluate the additional information and therapeutic impact resulting from ECO in these patients.
METHODS METHODS
We conducted a prospective study performing ECO on consecutive patients with ischemic stroke or transient ischemic attacks, admitted to our centre between February 2013 and May 2017.
RESULTS RESULTS
A total of 696 patients were included (female, 57.3%; mean age, 70 ± 15.3 years). Seven hundred thirty two echocardiographic examinations were performed (696 transthoracic and 36 transesophageal). Echocardiography yielded findings judged of clinical importance in 142 patients (20.4%, 95% CI 17.5-23.5). The most frequent of these were left atrial volume enlargement or a normal evaluation. Echocardiography findings resulted in changes in the management of 76 patients (10.7% 95% CI 8.8-13.4); initiation of anticoagulation therapy, administration of IV antibiotic therapy, cardiac surgeries, or other pharmacological therapies occurring in 42 cases (6%). The presence of coronary heart disease (OR: 2.64 95% CI 1.34-5.25), atrial fibrillation (OR: 0.24; 95% CI, 0.2-0.69), and admission NIHSS (OR: 1.04; 95% CI, 1.01-1.09), were the variables associated with changes in management.
CONCLUSIONS CONCLUSIONS
In unselected patients with acute ischemic stroke ECO had a low yield of additional information, and it changed management in a small percentage of patients.

Identifiants

pubmed: 30473460
pii: S1052-3057(18)30622-0
doi: 10.1016/j.jstrokecerebrovasdis.2018.10.042
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

562-568

Informations de copyright

Copyright © 2018. Published by Elsevier Inc.

Auteurs

Alejandro M Brunser (AM)

Unidad de Neurología Vascular, Servicio de Neurología, Departamento de Neurología y Psiquiatría, Clínica Alemana de Santiago. Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile. Electronic address: abrunser@alemana.cl.

Rodrigo Ibañez-Arenas (R)

Laboratorio de Ecocardiografía. Departamento de Cardiología Clínica Alemana de Santiago. Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile.

Martin Larico (M)

Departamento de Cardiología Clínica Alemana de Santiago. Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile.

Eloy Mansilla (E)

Unidad de Neurología Vascular, Servicio de Neurología, Departamento de Neurología y Psiquiatría, Clínica Alemana de Santiago. Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile.

Juan Almeida (J)

Unidad de Neurología Vascular, Servicio de Neurología, Departamento de Neurología y Psiquiatría, Clínica Alemana de Santiago. Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile.

Verónica V Olavarría (VV)

Unidad de Neurología Vascular, Servicio de Neurología, Departamento de Neurología y Psiquiatría y Departamento Paciente Crítico, Clínica Alemana de Santiago. Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile.

Paula Muñoz (P)

Unidad de Neurología Vascular, Servicio de Neurología, Departamento de Neurología y Psiquiatría y Departamento Paciente Crítico, Clínica Alemana de Santiago. Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile.

Alexis Rojo (A)

Unidad de Neurología Vascular, Servicio de Neurología, Departamento de Neurología y Psiquiatría, Clínica Alemana de Santiago. Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile.

Gabriel Cavada (G)

Unidad de Investigación y Ensayos Clínicos, Departamento Científico Docente, Clínica Alemana de Santiago.

Pablo M Lavados (PM)

Unidad de Neurología Vascular, Servicio de Neurología, Departamento de Neurología y Psiquiatría y Departamento Paciente Crítico, Clínica Alemana de Santiago. Facultad de Medicina, Universidad del Desarrollo, Santiago and Departamento de Ciencias Neurológicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile.

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Classifications MeSH