Synthesis and biological evaluation of new pyrazolone Schiff bases as monoamine oxidase and cholinesterase inhibitors.

Cholinesterase Inhibitors / chemical synthesis Dose-Response Relationship, Drug Humans Molecular Docking Simulation Molecular Structure Monoamine Oxidase Inhibitors / chemical synthesis Pyrazolones / chemical synthesis Schiff Bases / chemical synthesis Structure-Activity Relationship
Acetylcholinesterase Butyrylcholinesterase Docking Monoamine oxidase A Monoamine oxidase B Schiff base

Journal

Bioorganic chemistry
ISSN: 1090-2120
Titre abrégé: Bioorg Chem
Pays: United States
ID NLM: 1303703

Informations de publication

Date de publication:
03 2019
Historique:
received: 13 08 2018
revised: 12 11 2018
accepted: 13 11 2018
pubmed: 28 11 2018
medline: 16 1 2020
entrez: 28 11 2018
Statut: ppublish

Résumé

In the current work, Schiff base derivatives of antipyrine were synthesized. The chemical characterization of the compounds was confirmed using IR,

Identifiants

DOI: 10.1016/j.bioorg.2018.11.016 PMID: 30481645
pubmed: 30481645
pii: S0045-2068(18)30873-3
doi: 10.1016/j.bioorg.2018.11.016
pii:
doi:

Substances chimiques

Cholinesterase Inhibitors 0
Monoamine Oxidase Inhibitors 0
Pyrazolones 0
Schiff Bases 0
pyrazolone 39455-90-8

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

41-50

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Fatih Tok (F)

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Marmara University, İstanbul, Turkey.

Bedia Koçyiğit-Kaymakçıoğlu (B)

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Marmara University, İstanbul, Turkey.

Begüm Nurpelin Sağlık (BN)

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey; Doping and Narcotic Compounds Analysis Laboratory, Faculty of Pharmacy, Anadolu Universty, Eskişehir, Turkey.

Serkan Levent (S)

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey; Doping and Narcotic Compounds Analysis Laboratory, Faculty of Pharmacy, Anadolu Universty, Eskişehir, Turkey.

Yusuf Özkay (Y)

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey; Doping and Narcotic Compounds Analysis Laboratory, Faculty of Pharmacy, Anadolu Universty, Eskişehir, Turkey. Electronic address: yozkay@anadolu.edu.tr.

Zafer Asım Kaplancıklı (ZA)

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents cholinergiques › Anticholinestérasiques › Synthesis and biological evaluation of new...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Synthesis and biological evaluation of new...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Synthesis and biological evaluation of new...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Synthesis and biological evaluation of new...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Synthesis and biological evaluation of new...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibiteurs de la monoamine oxydase › Synthesis and biological evaluation of new...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Pyrazoles › Pyrazolones › Synthesis and biological evaluation of new...
questionsmedicales.fr › Composés chimiques organiques › Imines › Bases de Schiff › Synthesis and biological evaluation of new...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Synthesis and biological evaluation of new...